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Prostaglandin Antagonists

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Definition: Compounds that inhibit the action of prostaglandins.  /biosyn /physiol permitted if by living organism; DF: PG ANTAG   
See Also Cyclooxygenase Inhibitors 		Other names Prostaglandin Inhibitors; Inhibitor, Prostaglandin; Antagonist, Prostaglandin; Prostaglandin Inhibitor; Prostaglandin Antagonist; Inhibitors, Prostaglandin; Antagonists, Prostaglandin
Substances having this pharmacologic action: methional; betulinic acid; tolfenamic acid; baicalein; Polyphloretin Phosphate; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; flunixin meglumine; vapiprost; seratrodast; 6-isopropoxy-9-oxoxanthene-2-carboxylic acid; S 145
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
U 49619  130463-95-5   *Eicosanoids Prostaglandin Antagonists. Neuroendocrinology 1989;50(6):708
tiaprofenic acid  33005-95-7 5-benzoyl-alpha-methyl-2-thiopheneacetic acid  *Propionic Acids Prostaglandin Antagonists Photosensitizing Agents.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Chir Den Fr 46:105;1976; J Pharm Sci 66(7):1030;1977; J Steroid Biochem 10(4):471;1979; Phlebologie 29(1):69;1976; Rev Odontostomatol (Paris) 4(6):535;1975; Rev Odontostomatol 5(5):395;1976; Rheumatol Rehabil 1979;18(4):257
lonazolac  53808-88-1   *Pyrazoles Prostaglandin Antagonists.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Z Rheumatol 37(7-8):254;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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