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Prostaglandins E

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Definition: (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.  /biosyn /physiol permitted; /chem syn permitted: do not convert to PROSTAGLANDINS E, SYNTHETIC: DF: PGE   
Examples Dinoprostone 		Other names PGE; E, Prostaglandins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
17-isolevuglandin E4  0   *Prostaglandins E. J Org Chem 2000 Aug 25;65(17):5315-26
anhydrolevuglandin E2  121843-91-2   *Prostaglandins E. Prostaglandins 1992 Jun;43(6):573-82
prostaglandin-inositol cyclic phosphate  0   *Inositol Phosphates *Prostaglandins E. Adv Exp Med Biol 1986;211:409
Ro 22-1327  69900-71-6   *Prostaglandins E Prostaglandins E, Synthetic. J Cardiovasc Pharmacol 1987;9(3):285
levuglandin E2  91712-41-3   *Prostaglandins E. Adv Prostaglandin Thromboxane Leukotriene Res 1985;15:323
suppressor active peptide (thermal injury)  0   *Glycopeptides *Prostaglandins E Lymphocytes/immunology Neutrophils/immunology. J Clin Immunol 1985;5(3):172
11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid  24769-56-0 Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-epsilon,3-dioxo-, (1R-(1alpha,2beta,5beta))  *Prostanoic Acids Prostaglandins E/metabolism. Anal Biochem 1983;128(2):351
lymphocytic thyroid stimulator (non-immunoglobulin)  0   *Prostaglandins E *Prostaglandins F Lymphocytes Thyroid Gland. J Biol Chem 253(2):631;1978
6(9)-oxy-11,15-dihydroxy-prosta-7,13-dienoic acid  35121-77-8   *Prostaglandins E. Biochim Biophys Acta 424(2):323;1976
7 alpha-hydroxy-5,11-diketotetranorprostane-1,16-dioic acid  0   *Prostanoic Acids Prostaglandins E/metabolism. J Chromatogr 143(4):401;1977; J Chromatogr 1980;181(1):85; N E J Med 293(25):1278;1975; Prostaglandins 12(5):785;1976

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