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Prostaglandins F, Synthetic

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Definition: Analogs or derivatives of prostaglandins F that do not occur naturally in the body. They do not include the product of the chemical synthesis of hormonal PGF.  DF: PGF SYN   
Examples Carboprost; Cloprostenol 		Other names Prostaglandin F Analogs; PGF Synthetic; Synthetic, PGF; Analogues, Prostaglandin F; Analogs, Prostaglandin F; Synthetic Prostaglandins F; Prostaglandin F Analogues
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Xalacom  0   *Prostaglandins F, Synthetic *Timolol Drug Combinations Antihypertensive Agents Glaucoma/drug therapy. Oftalmologia. 2011;55(3):53-69
BOL 303259-X  0   *Prostaglandins F, Synthetic. Exp Eye Res. 2011 Sep;93(3):250-5.
7-(3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoic acid 6-(nitrooxy)hexyl amide  0   *Nitrates *Prostaglandins F, Synthetic. Exp Eye Res. 2011 Sep;93(3):243-9.
1-(nitrooxymethyl)-2-(nitrooxy)ethyl 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate  0   *Prostaglandins F, Synthetic. J Ocul Pharmacol Ther 2010 Apr;26(2):125-32
ACS67 compound  0   *Prostaglandins F, Synthetic Thioctic Acid/*analogs & derivatives. Invest Ophthalmol Vis Sci 2010 Jan;51(1):284-94
aroxaprostol  147335-23-7   *Prostaglandins F, Synthetic. Akush Ginekol (Mosk) 1992;(3-7):25-6
latanoprost  130209-82-4 Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate  *Prostaglandins F, Synthetic Intraocular Pressure/drug effects Neuroprotective Agents.
Pharma Action Antihypertensive Agents 		Arch Ophthalmol 1991;109(11):1564XALATAN; LATANOPROST
delprostenate  62524-99-6   *Prostaglandins F, Synthetic Dinoprost/*analogs & derivatives. Nippon Juigaku Zasshi 1986;48(5):863
luprostenol  73523-00-9   *Prostaglandins F, Synthetic. Vet Med Nauki 1986;23(4):54
nocloprost  79360-43-3   *Prostaglandins F, Synthetic.
Pharma Action Vasodilator Agents 		Biochim Biophys Acta 1986;860(1):91
1,1-dihomo-8-ketoprostaglandin F1alpha  71310-81-1   *Prostaglandins F, Synthetic. Biochim Biophys Acta 1985;837(1):67
5-oxa-17-phenyl-18,19,20-trinor prostaglandin F1 alpha methyl ester  55444-88-7   *Prostaglandins F, Synthetic. Biol Reprod 1984;30(4):886
tiaprost  62251-61-0   *Prostaglandins F, Synthetic *Thiophenes. DTW 1983;90(10):386
fenprostalene  69381-94-8   *Prostaglandins F, Synthetic.
Pharma Action Abortifacient Agents, Nonsteroidal 		J Pharm Sci 1983;72(8):946
2,3-dinor-6,15-diketo-13,14-dihydroprostaglandin F1alpha  68376-88-5 cyclopentanepentanoic acid, 3,5-dihydroxy-gamma-oxo-2-(3-oxooctyl)-, (1S-(1 alpha,2 beta,3 alpha,5 alpha))  *Prostaglandins F, Synthetic. Prostaglandins 1980;20(4):729
11-deoxyprostaglandin F1alpha  37785-98-1 prost-13-en-1-oic acid, 9,15-dihydroxy-, (9 alpha,13E,15S)  *Prostaglandins F, Synthetic. Prostaglandins 1980;19(4):559
6-methoxime prostaglandin F1alpha  0   *Prostaglandins F, Synthetic. Prostaglandins 1980;19(2):271
16,16-dimethyl-delta(4)-prostaglandin F1alpha  57931-23-4 (4Z,9 alpha,11 alpha,13E,15R)-9,11,15-trihydroxy-16,16-dimethylprosta-4,13-dien-1-oic acid  *Prostaglandins F, Synthetic. Prostaglandins 1979;18(5):745
15(S)-15-methyl delta(4)-prostaglandin F1alpha  65659-61-2 (4Z,9 alpha,11 alpha,13E,15S)-9,11,15-trihydroxy-15-methylprosta-4,13-dien-1-oic acid  *Prostaglandins F, Synthetic. Prostaglandins 1979;18(5):745
5,9-epoxy-16-phenoxy-prostaglandin F1  72657-07-9 Cyclopenta(b)pyran-2-butanoic acid, octahydro-6-hydroxy-5-(3-hydroxy-4-phenoxy-1-butenyl)-, (2R-(2alpha,4abeta,5beta(1E,3R*),6alpha,7abeta))  *Prostaglandins F, Synthetic. Adv Prostaglandin Thromboxane Res 1980;8:1521
fluprostenol  40666-16-8   *Prostaglandins F, Synthetic.
Pharma Action Luteolytic Agents 		Am J Obstet Gynecol 124(4):367;1976; J Reprod Fertil 1979;56(2):521; J Reprod Fertil 1979;suppl27:521; Prostaglandins 10(4):689;1975; Prostaglandins 10(4):715;1975; Prostaglandins 11(1):155;1976; Prostaglandins 7(2):141;1974; Vet Record 98(26):523;1976; Vet Record 99(2):26;1976
prostaglandin-ICI 74205  36950-85-3   *Prostaglandins F, Synthetic. Prostaglandins 2(5):375;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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