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Prostaglandins H

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Definition: A group of physiologically active prostaglandin endoperoxides. They are precursors in the biosynthesis of prostaglandins and thromboxanes. The most frequently encountered member of this group is the prostaglandin H2.  for analogs: coord with PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC if pertinant; /chem syn permitted: do not convert to PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC; PROSTAGLANDIN H2 is also available; DF: PGH   
Examples Prostaglandin H2 		Other names H, Prostaglandins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
11,9-epoxymethanoprostaglandin H1  72517-81-8 2-Oxabicyclo(2.2.1)heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, (1alpha,4alpha,5beta,6alpha(1E,3S*))-(+-)  *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
9,11-epoxymethanoprostaglandin H1  0   *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
11,9-epoxycarbonylprostaglandin H1  72580-46-2 2-Oxabicyclo(2.2.1)heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-3-oxo-, (1alpha,4alpha,5beta,6alpha(1E,3S*))-(+-)  *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
9,11-epoxycarbonylprostaglandin H1  0   *Prostaglandins H Prostaglandin Endoperoxides, Synthetic. Prostaglandins 18(4):529;1979
azo analog I  64192-56-9 9,11-azoprosta-5,13-dienoic acid  *Prostaglandins H Prostaglandins, Synthetic. Biochem Biophys Res Commun 79(1):305;1977; Biochim Biophys Acta 539:162;1978; Proc Natl Acad Sci USA 74(9):4007;1977; Prostaglandins 14(5):897;1977
azo analog II  67901-99-9 (5Z,9 alpha,11 alpha,13E,15S)-9,11-azo-15-hydroxyprosta-5,13-dienoic acid  *Prostaglandins H Prostaglandins, Synthetic. Life Sci 18:169;1976; Nature 273(5660):302;1978; Proc Natl Acad Sci USA 72(9):3355;1975; Proc Soc Exp Biol Med 153(2):209;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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