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Pteridines

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Definition: Compounds based on pyrazino[2,3-d]pyrimidine which is a pyrimidine fused to a pyrazine, containing four NITROGEN atoms.     
Examples Flavins; Pterins; Triamterene 		Other names Pyrazinopyrimidines; Pteridinones
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
penilumamide  0   *Pteridines Methionine/*analogs & derivatives. Org Biomol Chem 2010 May 7;8(9):2158-63
2-amino-6,7-bis(trifluoromethyl)-4-hydroxypteridine  0   *Pteridines. Nucleic Acids Symp Ser (Oxf) 2008;(52):115-6
BI 6727  0   *Pteridines. Clin Cancer Res 2009 May 1;15(9):3094-102
3-(2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol  0   *Phenols *Pteridines Phosphatidylinositol 3-Kinases/antagonists & inhibitors. J Pharmacol Exp Ther 2009 Mar;328(3):758-65
6,7-dimethyllumazine  0   *Pteridines Ligands. Chem Commun (Camb). 2008 Dec 28;(48):6588-90
6-acetyl-1,3,7-trimethylpteridine-2,4(1H,3H)-dione  0   *Pteridines Ligands. Dalton Trans 2008 Dec 7:(45):6461-6
8-benzyl pteridine-6,7-dione  0   *Pteridines. Bioorg Med Chem Lett 2008 Dec 1;18(23):6100-3
2,4-diamino-6-(2'-hydroxydibenz(b,f)azepin-5-yl)methylpteridine  0   *Benzazepines *Pteridines. Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):977-84
2-(N,N-dimethylaminomethyleneamino)-3-pivaloylpteridin-4-one  0   *Pteridines. J Pharmacol Sci 2008 Jun;107(2):221-5
NP 40208  0   *Pteridines. Basic Res Cardiol 2008 Jan;103(1):60-8
methyl 1-(4-((2,4-diaminopteridin-6-ylmethyl)methylamino)benzoyl)piperidine-4-carboxylate  0   *Isonipecotic Acids *Pteridines. Proc Natl Acad Sci U S A 2008 Feb 5;105(5):1448-53
methyl 1-(4-(2,4-diaminopteridin-6-ylmethylamino)benzoyl)piperidine-4-carboxylate  0   *Isonipecotic Acids *Pteridines. Proc Natl Acad Sci U S A 2008 Feb 5;105(5):1448-53
3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol  0   *Phenols *Pteridines Phosphatidylinositol 3-Kinases/antagonists & inhibitors. J Med Chem 2007 Sep 6;50(18):4279-94
BI 2536  0   *Pteridines. Curr Biol. 2007 Feb 20;17(4):304-15
4AZA1378  0   *Pteridines. Clin Immunol 2007 Jan;122(1):53-61
BI D1870  0   *Pteridines Ribosomal Protein S6 Kinases, 90-kDa/antagonists & inhibitors. Biochem J 2007 Jan 1;401(1):29-38
4AZA2096  0   *Pteridines. J Interferon Cytokine Res 2006 Aug;26(8):575-82
SD-208  0   *Pteridines. Am J Respir Crit Care Med 2005 Apr 15;171(8):889-98
6,7-dioxo-8-ribityllumazine  0   *Pteridines Ribitol/*analogs & derivatives. J Biol Chem 2006 Jan 13;281(2):1224-32
2-(N,N-dimethylaminomethyleneamino)-6-formyl-3-pivaloylpteridin-4-one  0   *Pteridines. Biochem Biophys Res Commun 2005 Aug 5;333(3):763-7
N-(3-methyl-4-oxo-3,4-dihydropteridin-2-yl)glycine  0   *Pteridines Glycine/*analogs & derivatives. Acta Crystallogr C. 2004 Nov;60(Pt 11):o795-7
2,4-diamino-6-(2'-O-(3-carboxypropyl)oxydibenz(b,f)azepin-5-yl)methylpteridine  0   *Benzazepines *Pteridines Tetrahydrofolate Dehydrogenase/antagonists & inhibitors. J Med Chem 2004 May 6;47(10):2475-85
Zn(cyclen)(lumazine)  0   *Organometallic Compounds Pteridines Zinc. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2543-6
6-methyl-8-(2-deoxyribofuranosyl)isoxanthopteridine  0   *Nucleosides *Pteridines. J Biol Chem 2003 Oct 24;278(43):42300-6
2-thiolumazine  0   *Pteridines. J Mol Model (Online) 2002 Aug;8(8);246-52
6-carboxyethyl-7-oxo-8-ribityllumazine  0   *Pteridines. Structure (Camb) 2002 Oct;10(10):1371-81
ethyl (8-((4-(diethylamino)-1-methylbutyl)amino)-2,3-diphenylpyrido(2,3-b)pyrazin-6-yl)carbamate  0   *Carbamates *Pteridines. J Antimicrob Chemother 2002 Jul;50(1):111-4
6,7-bis(trifluoromethyl)-8-ribityllumazine  0   *Pteridines. J Org Chem 2002 Apr 5;67(7):2087-92
N(alpha)-(4-(5-(2,4-diaminopteridin-6-yl)pent-1-yn-4-yl)benzoyl)-N(delta)-hemiphthaloylornithine  0   *Pteridines Ornithine/*analogs & derivatives. J Med Chem 2002 Apr 1;45(8):1690-6
4-amino-2,6-dimethyl-8-(2'-deoxy-beta-d-ribofuranosyl)-7(8H)-pteridone  0   *Pteridines Adenosine/*analogs & derivatives. Anal Biochem 2001 Nov 15;298(2):231-40
4-amino-6-methyl-8-(2-deoxy-beta-d-ribofuranosyl)-7(8H)-pteridone  0   *Pteridines Adenosine/*analogs & derivatives. Anal Biochem 2001 Nov 15;298(2):231-40
methyl 7-hydroxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylate  0   *Pteridines. Acta Crystallogr C 2001 May;57(Pt 5):608-10
Ro 08-2750  0   *Pteridines. J Neurosci Res 2000 Aug 1;61(3):263-72
RMKP 22  0   *Morpholines *Pteridines. Int J Pharm 2000 Mar 10;196(2):155-9
pterine-6-carboxylic acid  0   *Pteridines. J Pharm Biomed Anal 1999 Mar;19(3-4):269-75
N-((2,4-diaminopteridin-6-yl)methyl)dibenz(b,f)azepine  0   *Azepines *Pteridines Tetrahydrofolate Dehydrogenase/antagonists & inhibitors. J Med Chem 1999 Nov 18;42(23):4853-60
luminarosine  0   *Pteridines Ribose/*analogs & derivatives. Acta Biochim Pol 1998;45(4):941-8
2,4-diaminopteridine  0   *Pteridines. J Comput Aided Mol Des 1998 Mar;12(2):119-31
6-(trifluoromethyl)-7-oxo-8-ribityllumazine  143309-76-6   *Pteridines Fluorine Radioisotopes. Biochemistry 1994 Jun 21;33(24):7634-40
7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine  109577-83-5   *Piperazines *Pteridines. Cancer Res 1993 Jul 1;53(13):3058-61
1-(2-amino-4-oxopteridin-7-yl)-1-oxo-2,3,4-butanetriol-2,4-cyclic phosphate  122856-31-9   *Organophosphorus Compounds *Pteridines. J Biol Chem 1993 Jun 25;268(18):13493-8
pyrimido(5,4-g)pteridinetetrone 5-oxide, 1,3,7,9-tetrabutyl  33070-58-5   *Pteridines *Pyrimidines. Nucleic Acids Symp Ser 1991;25:59-60
2-amino-4-hydroxy-6-(3-hydroxy-4-phosphonoxy-1-butenyl)pteridine  136338-57-3   *Pteridines. Biochim Biophys Acta 1991;1074(3):439
2-amino-4-hydroxy-6-(1,2,3,4-tetrahydroxybutyl)pteridine  13392-23-9   *Pteridines. Biochim Biophys Acta 1991;1074(3):439
2,4-diamino-6-hydroxymethyl-7-hydroxypteridine  54643-27-5   *Pteridines. Eur J Biochem 1991;200(1):237
2,4-diamino-6-methyl-7-hydroxypteridine  19152-92-2   *Pteridines. Eur J Biochem 1991;200(1):237
2,4-diamino-6-chloromethylpteridine  57521-63-8   *Pteridines. Contact Dermatitis 1990;22(5):294
2,4-diamino-6-pteridinecarboxaldehyde  4261-17-0   *Pteridines. Photochem Photobiol 1986;44(2):231
pyrrofolic acid  88912-57-6 L-Glutamic acid, N-(4-(3-(2-amino-1,5-dihydro-4-oxo-6(4H)-pteridinylidene)-2,3-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)benzoyl)  *Pteridines. Arch Biochem Biophys 1986;251(1):260
6-methyl-7-(1',2'-dihydroxyethyl)-8-ribityllumazine  59936-28-6   *Pteridines. Genetika 1986;22(5):748
5,6,7,8-tetrahydropteridine  10593-78-9   *Pteridines. Josal Shika Daigaku Kiyp 1984;13(2):514
7-methyllumizine  13401-38-2   *Pteridines. J Bacteriol 1985;162(2):516
quinonoid-2-amino-4-hydroxy-6,7-dimethyldihydropteridine  5977-33-3   *Pteridines. Biochemistry 1984;23(14):3143
2,4-diamino-6-(bis-2-chloroethyl)aminomethylpteridine  93129-27-2 2,4-Pteridinediamine, 6-((bis(2-chloroethyl)amino)methyl)-, (R)  *Pteridines. Cancer Chemother Pharmacol 1984;13(2):73
2'-deoxysepialumazine  91261-64-2 Sepialumazine, 2'-deoxy-, (E)  *Pteridines. J Chromatogr 1984;290:303
biolumazine  94591-24-9 2,4(1H,3H)-Pteridinedione, 6-(1,2-dihydroxypropyl)-, (S-(R*,S*))  *Pteridines. J Chromatogr 1984;290:303
violapterin  2577-38-0   *Pteridines. J Biol Chem 1984;259(6):3526
2-amino-4-hydroxyaminopteridine  2236-60-4 4(1H)-Pteridinone, 2-amino  *Pteridines. J Biol Chem 1984;259(1):12
urothion  19295-31-9   *Pteridines. Proc Natl Acad Sci USA 1982;79(22):6856
8-(1'-D-ribityl)lumazine  0   *Pteridines. Methods Enzymol 1980;66:315
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