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Pulmonary Surfactants

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Definition: Substances and drugs that lower the SURFACE TENSION of the mucoid layer lining the PULMONARY ALVEOLI.  DF: PULM SURFACTANTS    Other names Surfactants, Pulmonary; Surfactant, Pulmonary; Pulmonary Surfactant
Substances having this pharmacologic action: Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; calfactant; poractant alfa; beractant
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
lucinactant  0   *Fatty Alcohols *Phosphatidylglycerols *Proteins Drug Combinations Pulmonary Surfactants. Pediatrics 2005 Apr;115(4):1018-29SURFAXIN
WMAP10 protein, recombinant  0   *Oligopeptides *Recombinant Proteins Pulmonary Surfactants. Eur J Biochem 1998 Jul 1;255(1):116-24
sinapultide  138531-07-4   *Peptides Pulmonary Surfactants. Clin Pharmacol Ther 1998 Jun;63(6):704
KL4 surfactant  0   *Peptides Pulmonary Surfactants. Am J Respir Crit Care Med 1996 Jan;153(1):404-10
SP-B protein (53-78)  0   *Peptide Fragments *Proteolipids Pulmonary Surfactants. Chem Phys Lipids 1994 May 6;71(1):47-59
colfosceril palmitate  63-89-8   1,2-Dipalmitoylphosphatidylcholine/*analogs & derivatives Pulmonary Surfactants. Lancet 1993 Jun 19;341(8860):1603
artificial lung expanding compound  0   *Phospholipids Pulmonary Surfactants. Arch Dis Child 1991;66(4):467
tubular myelin  0   *Myelin Sheath Pulmonary Surfactants. J Ultrastruct Res 64(3):352;1978
lecithins, disaturated  0   *Phosphatidylcholines Pulmonary Surfactants. Am J Obstet Gynecol 131(7):764;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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