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Putrescine

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Definition: A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine.     
Examples Spermidine 		Other names 1,4 Diaminobutane; 1,4 Butanediamine; Tetramethylenediamine; 1,4-Diaminobutane; 1,4-Butanediamine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cucullamide  0   Putrescine/*analogs & derivatives. Chem Pharm Bull (Tokyo). 2010;58(8):1116-8
methyl 1-(4-Hydroxy-5-(2-(3-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-2-oxoimidazolidin-1-yl)-3,3-dimethylbutanamido)-6-phenyl-1-(4-(pyridin-2-yl)phenyl)hexan-2-ylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamate  0   *Carbamates Putrescine/*analogs & derivatives HIV Protease. J Med Chem 2009 Apr 23;52(8):2571-86
N-hydroxy-N-succinylputrescine  0   *Succinates Putrescine/*analogs & derivatives. J Am Chem Soc 2008 Aug 13;130(32):10458-9
putrebactin  0   *Succinates Putrescine/*analogs & derivatives. J Am Chem Soc 2008 Aug 13;130(32):10458-9
IEM 1913  0   *Bridged Compounds Putrescine/*analogs & derivatives Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors Receptors, AMPA/antagonists & inhibitors. Eksp Klin Farmakol 2007 Jul-Aug;70(4):15-9
grandiamide D  0   Putrescine/*analogs & derivatives Alkaloids. J Nat Prod 2007 Oct;70(10):1640-3
gigantamide A  0   Putrescine/*analogs & derivatives Alkaloids. J Nat Prod 2007 Oct;70(10):1640-3
dasyclamide  0   Putrescine/*analogs & derivatives. J Nat Prod 2007 Oct;70(10):1640-3
putrescine-1,4-dicinnamide  0   Putrescine/*analogs & derivatives. Phytomedicine 2007 Feb;14(2-3):185-91
bisnaphthalimidopropyl putrescine  0   *Quinolones Putrescine/*analogs & derivatives. Int J Parasitol 2005 May;35(6):637-46
N,N'-bis-(prop-2-ynyl)-1,4-diaminobutane  0   Putrescine/*analogs & derivatives. Biochem Biophys Res Commun. 2005 Jan 14;326(2):483-90
palmitoylputrescine  0   Putrescine/*analogs & derivatives. J Nat Prod 2004 Aug;67(8):1283-6
diferuloylputrescine  0   Putrescine/*analogs & derivatives. Lipids 2001 Aug;36(8):839-44
p-coumaroyl-feruloylputrescine  0   *Coumaric Acids Putrescine/*analogs & derivatives. Lipids 2001 Aug;36(8):839-44
N-(4-azido-2-nitrophenyl)putrescine  0   Putrescine/*analogs & derivatives. Biochemistry 1998 Dec 22;37(51):17784-92
N1,N4-dibenzylputrescine  0   Putrescine/*analogs & derivatives. Cell Mol Biol (Noisy-le-grand) 1998 Jun;44(4):615-25
N(1),N(4)-bis(benzyl)-N(1),N(4)-bis(methyl)putrescine  0   Putrescine/*analogs & derivatives Ornithine Decarboxylase/antagonists & inhibitors. Eur J Pharmacol 1998 Jan 26;342(2-3):R1-R2
tetrahydroquino(4,3-b)benzazepine  0   *Benzazepines *Quinolines Putrescine/analogs & derivatives. Anticancer Res 1997 Nov-Dec;17(60):4327-32
N(1),N(4)-bis(7-chloroquinolin-4-yl)butane-1,4-diamine  0   *Aminoquinolines Putrescine/*analogs & derivatives Putrescine/antagonists & inhibitors. J Biol Chem 1997 May 23;272(21):13506-11
N,N-dimethyl-1,4-diamino-2-butene  0   Putrescine/*analogs & derivatives. Biochim Biophys Acta 1995 Nov 15;1253(1):117-27
N,N,N',N'-tetramethyl-1,3-butanediamine  97-84-7   Putrescine/*analogs & derivatives. Electrophoresis 1995 Apr;16(4):630-5
N,N,N',N'-tetraethyl-1,4-diaminobut-2-ene  20412-52-6   Putrescine/*analogs & derivatives. Biochem Soc Trans 1994 Nov;22(4):390S
N-(4-azidobenzoyl)putrescine  143693-47-4   *Azides Putrescine/*analogs & derivatives. Protein Sci 1992 Jan;1(1):132-44
PotE protein, E coli  0   *Antiporters *Escherichia coli Proteins Ornithine Putrescine. J Biol Chem 1991;266(31):20992
feruloylputrescine  501-13-3   *Coumaric Acids Putrescine/*analogs & derivatives Plant Extracts. Jpn J Pharmacol 1990;53(2):157
diacetylputrescine  3073-57-2   Putrescine/*analogs & derivatives. Biochem Int 1990;20(1):169
N-benzylputrescine  29867-04-7   Putrescine/*analogs & derivatives. Biol Chem Hoppe Seyler 1989;370(6):525
N-3-fluoropropylputrescine  132151-85-0   Putrescine/*analogs & derivatives. J Nucl Med 1989;30(7):1205
1,4-dimethylputrescine  37143-63-8   Putrescine/*analogs & derivatives. Biochim Biophys Acta 1988;972(3):239
2,2-difluoroputrescine  113741-09-6   Putrescine/*analogs & derivatives. Int J Biochem 1987;19(9):843
N(1),N(4)-diethylputrescine  27431-62-5   Putrescine/*analogs & derivatives. Cancer Res 1987;47(11):2821
2-fluoroputrescine  104613-90-3   Putrescine/*analogs & derivatives Fluorine Radioisotopes. Int J Rad Appl Instrum (A) 1986;37(7):607
2,2,3,3-tetrafluoroputrescine  356-56-9   Putrescine/*analogs & derivatives. Life Sci 1986;38(25):2307
aziridinyl putrescine  0   Putrescine/*analogs & derivatives. Biochem Pharmacol 1985;34(13):2409
MDL 72527  93565-01-6   Putrescine/*analogs & derivatives Oxidoreductases Acting on CH-NH Group Donors/antagonists & inhibitors. Biochim Biophys Acta 1985;838(1):69
N-methyl-N-(2,3-butadienyl)-1,4-butanediamine  93565-00-5   Putrescine/*analogs & derivatives. Biochim Biophys Acta 1985;838(1):69
N-methyl-N-(2-propenyl)-1,4-butanediamine  93565-03-8   Putrescine/*analogs & derivatives. Biochim Biophys Acta 1985;838(1):69
5,6-heptadiene-1,4-diamine  93065-08-8 5,6-Heptadiene-1,4-diamine, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (R)  Putrescine/*analogs & derivatives Ornithine Decarboxylase/antagonists & inhibitors. FEBS Lett 1984;174(2):275
alpha-(fluoromethyl)dehydroputrescine  82006-58-4   Putrescine/*analogs & derivatives Ornithine Decarboxylase/antagonists & inhibitors. J Med Chem 1983;26(11):1551
alpha-difluoromethylputrescine  86120-58-3 1,4-Pentanediamine, 5,5-difluoro  Putrescine/*analogs & derivatives Ornithine Decarboxylase/antagonists & inhibitors. Biochem Pharmacol 1982;31(23):3871
alpha-monofluoromethylputrescine  83306-45-0 1,2-Propanediamine, 3-fluoro-, (+-)  Putrescine/*analogs & derivatives Ornithine Decarboxylase/antagonists & inhibitors. Biochem J 1982;204(3):771
2-methyl-1,4-diaminobutane  15657-58-6 1,4-Butanediamine, 2-methyl  Putrescine/*analogs & derivatives. Experientia 1982;38(7):782
mono-4-coumarylputrescine  80244-08-2 2-Propenamide, N-(4-aminobutyl)-3-(4-hydroxyphenyl)-, monohydrochloride  Putrescine/*analogs & derivatives. Acta Virol 1981;25(2):115
N-acetylputrescine  5699-41-2   Putrescine/*analogs & derivatives. Biochem J 1980; 188(1):263
N-carbamoylputrescine  6851-51-0 urea, (4-aminobutyl)  Putrescine/*analogs & derivatives. J Gen Microbiol 1980;116(2):381
diaminobutene  18231-61-3 2-Butene-1,4-diamine  Putrescine/*analogs & derivatives. J Biochem (Tokyo) 86(1):191;1979
N-(phosphonoacetyl)putrescine  67023-07-8 Phosphonic acid, (2-((4-aminobutyl)amino)-2-oxoethyl)  Phosphonoacetic Acid/*analogs & derivatives Putrescine/*analogs & derivatives. FEBS Lett 88:94;1978
1,4-diaminobutanone  13123-70-1   Putrescine/*analogs & derivatives. Biochem J 166(3):635;1977; Biochem Soc Transact 6(2):407;1978; Febs Lett 75(1):180;1977
glutamylputrescine  58316-51-1   Putrescine/*analogs & derivatives. J Neurochem 26(1):115;1976
tetramethylputrescine  111-51-3   Putrescine/*analogs & derivatives. Lloydia 36(2):209;1973
2-hydroxyputrescine  539-59-3 1,4-diamino-2-butanol  Putrescine/*analogs & derivatives. J Biol Chem 248(7):2487;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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