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Pyrantel

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Definition: A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It is a drug of second-choice after benzimidazoles for treatment of ascariasis, hookworm, and pinworm infections, being effective after a single dose. (From Smith and Reynard, Textbook of Pharmacology, 1992, p920)  an antinematodal agent   
Pharmacological Action Antinematodal Agents; Neuromuscular Depolarizing Agents
Examples Pyrantel Pamoate; Pyrantel Tartrate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pyrantel citrate  5685-86-9   Pyrantel/*analogs & derivatives. Am J Vet Res 1981;42(5):871
quantrel  0   Drug Combinations Pyrantel/*analogs & derivatives. Southeast Asian J Trop Med Public Health 1980;11(4):502
oxantel  36531-26-7   Pyrantel/*analogs & derivatives. Am J Trop Med Hyg 24(4):563;1976; Am J Trop Med Hyg 25(6):914;1976; Drugs 15 (Suppl 1):70-78;1978; Drugs 15 (Suppl 1):94;1978; Proc Soc Exptl Biol Med 139(2):394;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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