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Pyrithioxin

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Definition: A neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.      Other names Hydrochloride, Pyritinol; Pyritinol Hydrochloride; Pyrithioxine; Piritoxina; Piritinol; Piriditol; Enerbol; Encephabol; Bonifen; Pyritinol; Pyridoxinedisulfide; Dipyridoxolyldisulfide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
JPC 80  55273-63-7   Pyrithioxin/*analogs & derivatives. J Rheumatol 1982;9(6):951
tamitinol  61711-37-3 3-Pyridinol, 4-(2-(ethylamino)ethyl)-2-methyl-5-((methylthio)methyl)  Pyrithioxin/*analogs & derivatives. Arzneim Forsch 28(9):1525;1978; Int Pharmacopsychiatry 13(3):177;1978; J Physiol 1979;295;84P
nicotinyl alcohol, pyritinol, drug combination  0   *Nicotinyl Alcohol *Pyrithioxin Drug Combinations Neurasthenia/drug therapy. Z Allgemeinmed 48(7):344;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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