encyclopedia of medical concepts
ψ 

Pyrophosphatases

More information in Books or onNLM PubMed
Definition: A group of enzymes within the class EC 3.6.1.- that catalyze the hydrolysis of diphosphate bonds, chiefly in nucleoside di- and triphosphates. They may liberate either a mono- or diphosphate. EC 3.6.1.-.     
Examples Inorganic Pyrophosphatase; Thiamine Pyrophosphatase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
alpha-farnesene synthase, E coli  EC 3.6.1.-   *Pyrophosphatases *Escherichia coli Proteins. Metab Eng. 2011 Nov;13(6):648-55.
ectonucleoside triphosphate diphosphohydrolase 6, human  EC 3.6.1.-   *Pyrophosphatases. Oncol Rep 2011 Jul;26(1):161-7
ITPA protein, mouse  EC 3.6.1.19   *Pyrophosphatases. Mutat Res. 2010 Nov 28;703(1):43-50
MESH1 protein, human  EC 3.6.1.-   *Pyrophosphatases. Nat Struct Mol Biol 2010 Oct;17(10):1188-94
TPSO3 protein, Arabidopsis  EC 5.5.-   *Multienzyme Complexes *Pyrophosphatases *Intramolecular Lyases *Arabidopsis Proteins. Plant Physiol 2010 Jul;153(3):1293-310
TPSO2 protein, Arabidopsis  EC 5.5.-   *Multienzyme Complexes *Pyrophosphatases *Intramolecular Lyases *Arabidopsis Proteins. Plant Physiol 2010 Jul;153(3):1293-310
Aps protein, Drosophila  EC 3.6.1.-   *Pyrophosphatases. Int J Biochem Cell Biol 2010 Jul;42(7):1174-81
NUDT16 protein, mouse  EC 3.6.1.-   *Pyrophosphatases. Nucleic Acids Res 2010 May;38(9):2891-903
Orf17 protein, E coli  EC 3.6.1.-   *Pyrophosphatases *Escherichia coli Proteins. DNA Repair (Amst) 2005 Jan 2;4(1):33-9
Nudt14 protein, mouse  EC 3.6.1.45   *Pyrophosphatases. Biochem Biophys Res Commun 2009 Dec 25;390(4):1414-8
NUDX7 protein, Arabidopsis  EC 3.6.1.-   *Pyrophosphatases *Arabidopsis Proteins. J Biol Chem 2009 Nov 20;284(47):741-54
MazG protein, E coli  EC 2.6.1.-   *Pyrophosphatases *Escherichia coli Proteins. J Mol Biol 2009 Sep 11;392(1):63-74
MTH2 protein, human  EC 2.6.1.-   *Pyrophosphatases. J Biol Chem 2009 Jul 17;284(29):19310-20
nudix pyrophosphatase 8, Thermus thermophilus  EC 3.6.1.-   *Bacterial Proteins *Pyrophosphatases. J Biol Chem 2009 Jun 5;284(23):15549-56
Ysa1 protein, S cerevisiae  EC 3.6.1.13   *Pyrophosphatases *Saccharomyces cerevisiae Proteins. J Biol Chem 2009 Apr 24;284(17):11256-66
Enpp3 protein, rat  EC 3.1.4.1   *Phosphoric Diester Hydrolases *Pyrophosphatases. J Cell Sci 2007 Mar 15;120(Pt 6):1009-16
Nudt16 protein, human  EC 3.6.1.-   *Pyrophosphatases. J Biol Chem 2007 Aug 24;282(34):24792-805
RS21-C6 protein, mouse  EC 3.6.1.23   *Pyrophosphatases. J Mol Biol. 2007 Apr 13;367(5):1405-12
DPP1 protein, S cerevisiae  EC 3.1.3.-   *Membrane Proteins *Pyrophosphatases *Saccharomyces cerevisiae Proteins. J Biol Chem 1998 Feb 6;273(6):3278-84
YffH protein, E coli  EC 3.6.1.-   *Pyrophosphatases *Escherichia coli Proteins. J Biol Chem 2006 Aug 11;281(32):22794-8
YmfB protein, E coli  EC 3.6.1.-   *Pyrophosphatases *Escherichia coli Proteins. J Biol Chem 2006 Aug 11;281(32):22794-8
YfaO protein, E coli  EC 3.6.1.-   *Pyrophosphatases *Escherichia coli Proteins. J Biol Chem 2006 Aug 11;281(32):22794-8
ITPA protein, human  EC 3.6.1.19   *Pyrophosphatases. Gut 2006 Jul;55(7):1048; author reply 1048-9
DcpS protein, C elegans  EC 3.6.1.-   *Pyrophosphatases *Caenorhabditis elegans Proteins. EMBO J 2002 Sep 2;21(17):4699-708
RP2 protein, mouse  EC 3.6.1.-   *Pyrophosphatases. Nucleic Acids Res 1986 Jul 11;14(13):5159-70
Npp2 protein, S cerevisiae  EC 3.-   *Hydrolases *Saccharomyces cerevisiae Proteins Phosphoric Diester Hydrolases Pyrophosphatases. Eukaryot Cell 2005 Nov;4(11):1892-901
Npp1 protein, S cerevisiae  EC 3.-   *Hydrolases *Saccharomyces cerevisiae Proteins Phosphoric Diester Hydrolases Pyrophosphatases. Eukaryot Cell 2005 Nov;4(11):1892-901
YjjX protein, E coli  EC 3.6.1.-   *Pyrophosphatases. Structure 2005 Oct;13(10):1511-20
undecaprenyl pyrophosphate phosphatase  EC 3.6.1.-   *Pyrophosphatases. J Biol Chem 2005 Aug 12;280(32):28852-7
X29 protein, Xenopus  EC 3.6.1.-   *Pyrophosphatases *Xenopus Proteins RNA-Binding Proteins. Mol Cell 2004 Mar 26;13(6):817-28
ENTPD4 protein, human  EC 3.6.1.6   *Pyrophosphatases. BMC Biochem 2004 Jun 16;5(1);8
Lysal2 protein, mouse  EC 3.6.1.5   *Pyrophosphatases.
VSP1 protein, Trypanosoma brucei  EC 3.6.1.-   *Pyrophosphatases *Protozoan Proteins. J Biol Chem 2004 Jan 30;279(5):3420-5
NUDT12 protein, human  EC 3.6.1.-   *Pyrophosphatases. Biochem J 2003 Sep 1;374(Pt 2);329-35
RdgB protein, E coli  EC 3.6.1.-   *Pyrophosphatases *Escherichia coli Proteins DNA Repair. J Bacteriol 2003 May;185(10):3101-10
NUDT1 protein, Arabidopsis  EC 3.6.1.-   *Pyrophosphatases *Arabidopsis Proteins. J Biol Chem 2002 Dec 27;277(52):50482-6
Dolpp1 protein, mouse  EC 3.6.1.43   *Pyrophosphatases. J Biol Chem 2002 Nov 22;277(47):45226-34
NUDT10 protein, human  EC 3.6.1.-   *Pyrophosphatases. BMC Biochem 2002 Jul 16;3(1):20
NUDT11 protein, human  EC 3.6.1.-   *Pyrophosphatases. BMC Biochem 2002 Jul 16;3(1):20
UDP-2,3-diacylglucosamine pyrophosphatase  EC 3.6.1.-   *Pyrophosphatases Escherichia coli Proteins. J Biol Chem 2002 Jul 19;277(29):25937-46
diphosphonucleotide phosphatase-phosphodiesterase 2  EC 3.6.1.-   *Phosphoric Diester Hydrolases *Pyrophosphatases. FEBS Lett 2002 May 22;519(1-3):159-63
diphosphonucleotide phosphatase-phosphodiesterase 1  EC 3.6.1.-   *Phosphoric Diester Hydrolases *Pyrophosphatases. FEBS Lett 2002 May 22;519(1-3):159-63
pyrophosphatase, Aquifex aeolicus  EC 3.6.1.-   *Bacterial Proteins *Pyrophosphatases. Protein Expr Purif 2001 Nov;23(2):242-8
nucleoside-triphosphate diphosphohydrolase 3  EC 3.6.1.-   *Pyrophosphatases. Arch Biochem Biophys 2001 Nov 1;395(1):94-102
NadN protein, Haemophilus influenzae  EC 3.6.1.-   *Bacterial Proteins *Nucleotidases *Pyrophosphatases. J Bacteriol 2001 Jul;183(13):3974-81
NUDT9  EC 3.6.1.-   *Pyrophosphatases. Nature 2001 May 31;411(6837):595-9
ENPP3 protein, human  0   *Phosphoric Diester Hydrolases *Pyrophosphatases. Blood 2001 May 15;97(10):3303-5
NPY1 protein, S cerevisiae  EC 3.6.1.-   *Pyrophosphatases *Saccharomyces cerevisiae Proteins. Arch Biochem Biophys 2001 Apr 1;388(1):18-24
TVP protein, Thermotoga maritima  EC 3.6.1.-   *Bacterial Proteins *Pyrophosphatases. FEBS Lett 2001 May 4;496(1):6-11
nudix hydrolase Orf135  EC 3.6.1.-   *Pyrophosphatases. J Biol Chem 2001 Feb 23;276(8):5421-6
nucleoside triphosphate diphosphohydrolase 6  EC 3.6.1.-   *Pyrophosphatases. Biochem J 2000 Nov 1;351 Pt 3:639-47
triphenyltin salicylate  0   *Organotin Compounds *Salicylates Pyrophosphatases. J Enzyme Inhib 2000 Jun;15(4):411-20
nucleotide pyrophosphatase - phosphodiesterase I  EC 3.6.1.-   *Phosphoric Diester Hydrolases *Pyrophosphatases. Biochem J 2000 Feb 15;346( Pt 1):25-31
NUDT5 protein, human  EC 3.6.1.-   *Pyrophosphatases. Biochem J 1999 Dec 1;344( Pt 2):331-7
aps1 protein, S pombe  EC 3.6.1.-   *Pyrophosphatases *Schizosaccharomyces pombe Proteins. Biochemistry 1999 mar 23;38(12):3649-55
SLR0787 protein, Synechocystis  EC 2.7.7.1   *Bacterial Proteins *Nicotinamide-Nucleotide Adenylyltransferase *Pyrophosphatases. FEBS Lett 1999 Feb 12;444(2-3):222-6
CAX4 protein, S cerevisiae  0   *Pyrophosphatases *Saccharomyces cerevisiae Proteins. Glycobiology 1999 Mar;9(3):243-53
ENTPD5 protein, human  EC 3.6.1.-   *Pyrophosphatases *Oncogene Proteins. Oncogene 1999 Jan 21;18(3):689-701
Nurf-38 protein, Drosophila  EC 3.6.1.1   *Pyrophosphatases *Drosophila Proteins. Genes Dev 1998 Oct 15;12(20):3206-16
CILP protein, human  EC 3.6.1.-   *Pyrophosphatases *Extracellular Matrix Proteins Glycoproteins. J Biol Chem 1998 Sep 4;273(36):23463-8
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy