encyclopedia of medical concepts
ψ 
ψ 
ψ 

Pyrrolidonecarboxylic Acid

More information in Books or onNLM PubMed
Definition: A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.      Other names Pidolate, Magnesium; Acid, Pyrrolidonecarboxylic; Acid, Pyroglutamic; Pyroglutamate; Magnesium Pidolate; 5-Oxopyrrolidine-2-Carboxylic Acid; 5-Ketoproline; Pyroglutamic Acid; Pidolic Acid; 5-Oxoproline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(4-methoxy-3-methyl-2-oxo-2H-pyran-6-yl)butylpyroglutamate  0   *Pyrans Pyrrolidonecarboxylic Acid/*analogs & derivatives. J Asian Nat Prod Res. 2011 Oct;13(11):1042-6
4-aminopyroglutamate  0   Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biopolymers. 2004 Dec 5;75(5):412-9
BLAS 236  0   *Quaternary Ammonium Compounds *Pyridines Pyrrolidonecarboxylic Acid/*analogs & derivatives. Clin Cancer Res 2003 Nov 15;9(15):5776-85
glucagon-like peptide-1 (7-36)amide, N-pyroglutamyl  0   *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives Glucagon-Like Peptide 1/*analogs & derivatives. J Endocrinol 2004 Mar;180(3):379-88
(S)-ethyl 4,4-dimethyl pyroglutamate  0   Pyrrolidonecarboxylic Acid/*analogs & derivatives. Org Lett. 2003 Oct 16;5(21):3791-4
oleyl pyroglutamate  0   Pyrrolidonecarboxylic Acid/*analogs & derivatives. Yao Xue Xue Bao 2003 May;38(5):384-7
pyroglutamyl-tyrosyl-prolylamide  0   Pyrrolidonecarboxylic Acid/*analogs & derivatives Thyrotropin-Releasing Hormone/*analogs & derivatives. Neurochem Int 2002 Dec;41(6):415-28
gonadotropin-releasing hormone-III  0   *Gonadotropin-Releasing Hormone Pyrrolidonecarboxylic Acid/*analogs & derivatives. Endocrinology 1993 Mar;132(3):1125-31
blomhotin  0   *Crotalid Venoms Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biol Pharm Bull 2000 Nov;23(11):1379-81
N(I),N(II),N(III),N(IV)-tetraacetyl-NV-dimethylaminophenylazophenylthioureido-beta-chitopentaosyl-pyroglutamyl amidoethylnaphthalenesulfonic acid  0   *Oligosaccharides Pyrrolidonecarboxylic Acid/*analogs & derivatives Thiourea/*analogs & derivatives. Eur J Biochem 2000 Sep;267(17):5593-600
pyroglutamyl-naphthylamide  0   *Naphthalenes Pyrrolidonecarboxylic Acid/*analogs & derivatives. Folia Biol (Praha) 1998 ;44(6):213-6
pyroglutamyl-leucyl-prolinamide  0   Pyrrolidonecarboxylic Acid/*analogs & derivatives Thyrotropin-Releasing Hormone/*analogs & derivatives. J Med Chem 1999 Nov 4;42(22):4572-83
glutaminyl-pyroglutamyl-glutamyl-proline amide  0   Thyrotropin-Releasing Hormone/*analogs & derivatives Pyrrolidonecarboxylic Acid/*analogs & derivatives. Mol Reprod Dev 1998 Dec;51(4):468-76
pyroglutamyl-alanyl-tyrosine  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biochim Biophys Acta 1998 Oct 14;1388(1):45-52
NC 1900  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Arginine Vasopressin. Eur J Pharmacol 1998 Jul 10;352(2-3):135-42
pyroglutamyl-glutaminyl-tryptophan  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Crotalid Venoms. Biochem Biophys Res Commun 1998 Jul 30;248(3):562-8
pyroglutamyl-asparagyl-tryptophan  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Crotalid Venoms. Biochem Biophys Res Commun 1998 Jul 30;248(3):562-8
pyroglutamyl-lysyl-tryptophan  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Crotalid Venoms. Biochem Biophys Res Commun 1998 Jul 30;248(3):562-8
PG-KII peptide  0   *Tachykinins Pyrrolidonecarboxylic Acid/*analogs & derivatives. Peptides 1996;17(4):729-31
SK&F 108636  155215-78-4   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Stem Cells (Dayt) 1996 Mar;14(2):215-24
pyroglutamic acid 7-amino-4-methylcoumarin  0   *Coumarins Pyrrolidonecarboxylic Acid/*analogs & derivatives. Int J Pept Protein Res 1996 Jul;48(1):56-8
pyroglutamyltryptophan  0   *Dipeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Drug Carriers. Pharmazie 1996 Jul;51(7):487-9
pyroglutamyl-phenylalanyl-prolyl-N-methyl-psi(5-tetrazole)  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Thyrotropin-Releasing Hormone. Acta Crystallogr C 1995 Dec 15;51(Pt 12):2575-9
lamprey GnRH-I  0   Gonadotropin-Releasing Hormone/*analogs & derivatives Pyrrolidonecarboxylic Acid/*analogs & derivatives. J Biol Chem 1986 Apr 15;261(11):4812-9
pyroglutamylglycine  29227-88-1   *Dipeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. J Ocul Pharmacol Ther 1995 Spring;11(1):65-71
pyroglutamyl-L-DOPA-proline  0   *Oligopeptides Levodopa/*analogs & derivatives Pyrrolidonecarboxylic Acid/*analogs & derivatives. Pharm Res 1995 Jul;12(7):1101-4
pyroglutamyl-leucyl-threonyl-phenylalanyl-threonyl-prolyl-asparaginyl-tryptophyl-glycyl-serinamide  0   *Neuropeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Regul Pept 1995 Jun 27;57(3):247-52
pyroglutamyl-leucyl-asparaginyl-phenylalanyl-seryl-threonyl-glycyl-tryptophanamide  0   *Neuropeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Regul Pept 1995 Jun 27;57(3):247-52
pyroglutamyl-prolyl-asparaginyl-prolyl-aspartyl-glutamyl-phenylalanyl-phenylalanyl-glycyl-leucyl-methioninamide  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Peptides 1995;16(4):609-14
adipokinetic hormone, Magicicada  0   *Insect Hormones *Neuropeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Insect Biochem Mol Biol 1995 Sep;25(8):929-32
substance P (5-11), Glp(5)-Glu(O-benzyl)(11)  0   *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives Substance P/*analogs & derivatives Receptors, Neurokinin-1/agonists. Int J Pept Protein Res 1995 Jun;45(6):508-13
substance P (6-11), Glp(6)-Glu(O-benzyl)(11)  0   *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives Substance P/*analogs & derivatives Receptors, Neurokinin-1/agonists. Int J Pept Protein Res 1995 Jun;45(6):508-13
cardioacceleratory peptide 2b  0   *Neuropeptides *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. FEBS Lett 1995 Sep 11;371(3):311-4
calcium pidolate  31377-05-6   Pyrrolidonecarboxylic Acid/*analogs & derivatives. Osteoporos Int 1995 Jan;5(1):66-7
ethyl N-methyl-4-hydroxy-5-oxo-3-pyrroline-3-carboxylate iron chelate  4450-97-9   Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biotech Histochem 1994 Sep;69(5):263-7
GPAnt-2  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Substance P. Cell Mol Biol (Noisy-Le-grand) 1994 Jul;40(5):707-15
metamorphosin A  157622-03-2   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Metamorphosis, Biological. Dev Biol 1994 Jun;163(2):440-6
phyllolitorin, des-Trp-3,Leu-8  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Bombesin. Brain Res 1994 Feb 21;637(1-2):331-4
locustapyrokinin II  151812-20-3   *Neuropeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Comp Biochem Physiol (C) 1993 Sep;106(1):103-9
2-deoxy-2-(2-fluoro-3-hydroxytetradecanamido)-3-O-(3-hydroxytetradecanoyl)-4-O-phosphonoglucopyranose  146452-52-0   Lipid A/*analogs & derivatives Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biosci Biotechnol Biochem 1993 Sep;57(9):1526-9
pyroglutamylglutamine diketopiperazine  151367-91-8   *Piperazines *Peptides, Cyclic Pyrrolidonecarboxylic Acid/*analogs & derivatives. Int J Pept Protein Res 1993 Jul;42(1):14-9
pyroglutamylasparagine diketopiperazine  151367-95-2   *Peptides, Cyclic *Piperazines Pyrrolidonecarboxylic Acid/*analogs & derivatives. Int J Pept Protein Res 1993 Jul;42(1):14-9
pyroglutamyl-leucyl-tryptophan methyl ester  98385-67-2 L-Tryptophan, N-(N-(5-oxo-L-prolyl)-L-leucyl)-, methyl ester  *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Immunopharmacology 1993 Jan-Feb;25(1):51-63
substance P (6-11), pGlu(6)-N-MePhe(8)-Aib(9)  0   *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives Substance P/*analogs & derivatives. Biopolymers 1993 Jun;33(6):915-26
pyroglutamyl-histidyl-tryptophyl--seryl-tyrosyl-tryptophyl-leucyl-arginyl-prolyl-glycinamide  0   Gonadotropin-Releasing Hormone/*analogs & derivatives Pyrrolidonecarboxylic Acid/*analogs & derivatives. Ann N Y Acad Sci 1993 May 28;687:250-4
pyroglutamyl-asparaginamide  103322-29-8   *Dipeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Eksp Klin Farmakol 1992 Sep-Oct;55(5):6-8
pyroglutamyl-leucyl-glycyl-arginyl-phenylalaninamide  148297-92-1   *Neuropeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Comp Biochem Physiol (B) 1993 Feb;104(2):235-40
eisenin  21477-57-6   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Algal Proteins. J Immunother 1993 Jan;13(1):36-42
LHRH cysteamide, des-Arg  144700-79-8   *Peptide Fragments Gonadotropin-Releasing Hormone/*analogs & derivatives Pyrrolidonecarboxylic Acid/*analogs & derivatives. Pept Res 1992 Jul-Aug;5(4):233-40
2,4-dihydroxy-3,3,4-trimethylpyroglutamic acid  143785-44-8   Pyrrolidonecarboxylic Acid/*analogs & derivatives. Carbohydr Res 1992 Jul 2;231:147-58
pyroglutamyl-tyrosyl-prolinamide  70650-88-3   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. J Biol Chem 1992 Sep 5;267(25):17508-11
pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl methyl ester  51871-39-7   *Gonadotropin-Releasing Hormone *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biomed Biochim Acta 1991;50(10-11):205-8
pyroglutamyl-phenylalanyl-prolinamide  34783-35-2 L-Prolinamide, 5-oxo-L-prolyl-L-phenylalanyl  *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives Semen. J Biol Chem 1992 Apr 15;267(11):7464-9
pyroglutamyl-alanyl-glutamyl-seryl-asparagine  0   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biochem Biophys Res Commun 1992 Mar 16;183(2):474-80
pyroglutamyl-tryptophyl-leucyl-lysyl-glycyl-arginyl-phenylalaninamide  0   *Neuropeptides *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Biochem Biophys Res Commun 1992 Mar 16;183(2):375-82
pyroglutamyl-glutamyl-glycyl-seryl-asparagine  129276-54-6   *Oligopeptides Pyrrolidonecarboxylic Acid/*analogs & derivatives. Cancer Res 1992 Mar 1;52(5):1218-21
protirelin, Nle(2)-Prot(3)  0   Pyrrolidonecarboxylic Acid/*analogs & derivatives Thyrotropin-Releasing Hormone/*analogs & derivatives. Gen Physiol Biophys 1991;10(3):287
substance P (6-11), pGlu(6)-Phe(8)-psi-(methyleneoxy)-Gly(9)  98900-29-9   *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives Substance P/*analogs & derivatives. J Med Chem 1991;34(8):2430
thyrotropin-releasing hormone, 2-diazohistidinyl  81222-52-8   Pyrrolidonecarboxylic Acid/*analogs & derivatives Thyrotropin-Releasing Hormone/*analogs & derivatives. J Recept Res 1991;11(1-4):371
substance P (6-11), Glp(6)-iodo-Tyr(8)  70082-71-2   *Peptide Fragments Pyrrolidonecarboxylic Acid/*analogs & derivatives Substance P/*analogs & derivatives. Int J Biochem 1991;23(3):317
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy