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Pyruvate Kinase

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Definition: ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40.  do not coord L-, R-, M-, M1- or M2-type pyruvate kinase with ISOENZYMES   
See Also Anemia, Hemolytic
Other names M2 Type Pyruvate Kinase; M1 Type Pyruvate Kinase; M Type Pyruvate Kinase; L Type Pyruvate Kinase; R-Type Pyruvate Kinase; Pyruvate Kinase L; M2-Type Pyruvate Kinase; M1-Type Pyruvate Kinase; M-Type Pyruvate Kinase; L-Type Pyruvate Kinase; R Type Pyruvate Kinase; Pyruvate Kinase, R-Type; Pyruvate Kinase, M2-Type; Pyruvate Kinase, M1-Type; Pyruvate Kinase, M-Type; Pyruvate Kinase, L-Type
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pyruvate kinase Mallorca  EC 2.7.1.-   *Pyruvate Kinase. Haematologica 2000 Mar;85(3):227-32

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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