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Receptors, Antigen, T-Cell

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Definition: Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (ANTIGENS, CD3). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.  GEN; prefer specifics; do not confuse their gamma-delta chains with gamma & delta chains which are subunits of CD3 antigens (index under ANTIGENS, CD3); DF: RECEPT ANTIGEN T CELL   
See Also Antigens, CD3; Gene Rearrangement, T-Lymphocyte; Genes, T-Cell Receptor
Examples Complementarity Determining Regions; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta 		Other names T-Cell Receptors; Antigen Receptors, T-Cell; T-Cell Antigen Receptors; T Cell Receptors; T Cell Receptor; T Cell Antigen Receptor; Receptors, T-Cell; Receptors, T Cell Antigen; Receptor, T-Cell Antigen; Receptor, T-Cell; Antigen Receptors, T Cell; Antigen Receptor, T-Cell; T-Cell Receptor; T-Cell Antigen Receptor; Receptors, T-Cell Antigen
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Valpha24 protein, human  0   *Receptors, Antigen, T-Cell. Cancer Sci 2008 Apr;99(4):638-45
Sts-1 protein, mouse  0   *Receptors, Antigen, T-Cell. Immunity. 2004 Jan;20(1):37-46
Sts-2 protein, mouse  0   *Receptors, Antigen, T-Cell. Immunity. 2004 Jan;20(1):37-46
CD3 epsilon, wallaby  0   *Receptors, Antigen, T-Cell Signal Transduction. Mol Immunol 2001 Sep;38(5):359-64
antigen T cell receptor, eta-kappa  0   *Receptors, Antigen, T-Cell. Mol Cell Biochem 1999 May;195(1-2):47-53
antigenic peptide Ealpha52-68  0   *Peptide Fragments *Receptors, Antigen, T-Cell Histocompatibility Antigens Class II. J Blood Sci 1999 Jan;6(1):53-63
pTAC12 protein, mouse  0   *Membrane Glycoproteins Receptors, Antigen, T-Cell. J Biol Chem 1998 Nov 13;273(46):30675-9
CD3E protein, human  0   *Antigens, CD3 Receptors, Antigen, T-Cell Signal Transduction. J Immunol 1998 Nov 1;161(9):4591-8
TCRzeta protein, Bos taurus  0   *Receptors, Antigen, T-Cell. Gene 1996 May 9;169(2):165-71
CD3epsilon protein, bovine  0   *Receptors, Antigen, T-Cell Signal Transduction. Gene 1996 Mar 9;169(2):165-71
CD150 antigen  169535-43-7   *Receptors, Cell Surface *Antigens, CD Receptors, Antigen, T-Cell Receptors, Virus Antigens, CD. Nature 1995 Jul 20;376(6537):260-3
antigen T cell receptor, iota chain  0   *Receptors, Antigen, T-Cell. Eur J Immunol 1995 May;25(5):1405-9
CD8 receptor  0   *Receptors, Antigen, T-Cell Antigens, CD8. Acta Derm Venerol (Stockh) 1990;70(5)395
T cell receptor-V(beta)8-39-59 peptide  0   *Peptide Fragments *Receptors, Antigen, T-Cell. Science 1991;251(4992):430
antigen T cell receptor, epsilon chain  0   *Receptors, Antigen, T-Cell. EMBO J 1989;8(9):2527
MLR3 activation antigen  0   *Antigens, Surface *Receptors, Antigen, T-Cell Lymphocyte Activation. Eur J Immunol 1989;19(2):323
antigen T cell receptor, zeta chain  0   *Receptors, Antigen, T-Cell. Science 1988;239(4843):1018

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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