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Receptors, Histamine

More information in Books or onNLM PubMed
Definition: Cell-surface proteins that bind histamine and trigger intracellular changes influencing the behavior of cells. Histamine receptors are widespread in the central nervous system and in peripheral tissues. Three types have been recognized and designated H1, H2, and H3. They differ in pharmacology, distribution, and mode of action.  GEN or unspecified; prefer specifics; coord IM with specific histamine cpd (IM); DF: RECEPT HISTAMINE   
Examples Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3 		Other names Histamine Receptors; Histamine Binding Sites; Sites, Histamine Binding; Receptor, Histamine; Binding Sites, Histamine; Histamine Receptor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N1-acetyl-N2-(3-(1H-imidazol-4-yl)propyl)guanidine  0   *Guanidines *Imidazoles Receptors, Histamine. J Med Chem 2009 Apr 23;52(8):2623-7
4-(piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro(2,3-h)quinazolin-2-amine  0   *Benzofurans *Quinazolines Receptors, Histamine. J Med Chem 2008 Nov 27;51(22):7094-8
EV131 protein, Rhipicephalus appendiculatus  0   *Receptors, Histamine Ticks. Ann N Y Acad Sci 2005 Nov;1056:197-205
S-(2-guanidylethyl)isothiourea  0   *Guanidines Thiourea/*analogs & derivatives Receptors, Histamine. Radiat Res 1957 Jul;7(1):22-34
Hrh4 protein, mouse  0   *Receptors, Histamine *Receptors, G-Protein-Coupled.
Hrh4 protein, rat  0   *Receptors, Histamine *Receptors, G-Protein-Coupled.
1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine  0   *Indoles *Piperazines Receptors, Histamine. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13
ora transientless protein, Drosophila  0   *Chloride Channels *Drosophila Proteins Receptors, Histamine. Nat Neurosci 2002 Jan;5(1):11-2
AXOR35 receptor  0   *Receptors, Histamine. Mol Pharmacol 2001 Mar;59(3):434-41
HRH4 protein, human  0   *Receptors, Histamine *Receptors, G-Protein-Coupled. Biochem Biophys Res Commun 2000 Dec 20;279(2):615-20; J Biol Chem 2000 Nov 24;275(47):36781-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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