encyclopedia of medical concepts
ψ 
ψ 
ψ 

Receptors, Histamine H1

More information in Books or onNLM PubMed
Definition: A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)  receptors for only the classical "antihistaminics"; DF: RECEPT H1    Other names Histamine H1 Receptors; Receptor, Histamine H1; H1 Receptors, Histamine; H1 Receptor, Histamine; Receptors, H1; Histamine H1 Receptor; H1 Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
phenoprodifen  0   *Imidazoles Receptors, Histamine H1 Histamine Agonists. Biochem Pharmacol. 2011 Dec 15;82(12):1910-8.
4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-ylbut-2-enyloxy)acetic acid  0   *Acetic Acids *Piperazines Receptors, Histamine H1. Drugs R D 2008;9(2):93-112
N-(1-((6-fluoro-2-naphthyl)methyl)pyrrolidin-3-yl)-2-(1-((6-methylpyridazin-3-yl)carbonyl)piperidin-4-ylidene)acetamide  0   *Piperidines *Pyridazines Receptors, Histamine H1. Eur J Pharmacol 2007 Jun 1;563(1-3):224-32
5-phenyl-7-dimethylamino-5,6,7,8-tetrahydro-9H-benzocycloheptane  0   *Bicyclo Compounds *Dimethylamines Receptors, Histamine H1. Neurosci Lett 2006 Oct 30;407(3):249-53
5,6-dihydrospiro(11H-imidazo(2,1-b)(3)benzazepine-11,4'-piperidine)-3-carboxamide  0   *Benzazepines *Spiro Compounds Receptors, Histamine H1/antagonists & inhibitors. J Med Chem 2005 Mar 24;48(6):2154-66
histapendifen  0   Histamine/*analogs & derivatives Receptors, Histamine H1/antagonists & inhibitors. J Med Chem 2003 Dec 18;46(26):5812-24
histabudifen  0   Histamine/*analogs & derivatives Receptors, Histamine H1/antagonists & inhibitors. J Med Chem 2003 Dec 18;46(26):5812-24
2-(2-(3-(3-fluorophenyl)-3-phenylpropyl)-1H-imidazol-4-yl)ethanamine  0   *Imidazoles Receptors, Histamine H1/agonists. Eur J Med Chem 2000 Jan;35(1):41-52
2-((3-trimethyl)diphenyl)histamine  0   Histamine/*analogs & derivatives Receptors, Histamine H1. Yale J Biol Med 1997 Jan-Feb;69(1):9-19
SK&F 94461  101395-32-8   Pyrilamine/*analogs & derivatives Receptors, Histamine H1. Mol Pharmacol 1988;34(2):136

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy