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Receptors, Histamine H2

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Definition: A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate adenylate cyclase. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)  receptors for the non-classical antihistaminics (HISTAMINE H2 ANTAGONISTS); DF: RECEPT H2    Other names Histamine H2 Receptors; H2 Receptors, Histamine; Receptors, H2; H2 Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FR-A 19  141099-46-9   *Guanidines *Imidazoles Receptors, Histamine H2. Agent Actions 1992 Mar;34(3-4):185-91
BU-E 75  114667-74-2   *Guanidines *Imidazoles Receptors, Histamine H2. Agents Actions Suppl 1991;33:257
VUF 8414  102203-15-6   *Imidazoles Receptors, Histamine H2. J Recept Res 1989-90;9(6):417
tidazin  74238-99-6   *Receptors, Histamine H2. Proc Natl Acad Sci USA 1981;59(1):45
diphenethindole  72601-09-3 Pyrazino(1',2':1,6)pyrido(3,4-b)indole, 2-(2-(diphenylmethoxy)ethyl)-1,2,3,4,6,7,12,12a-octahydro  *Indoles Receptors, Histamine H2. Indian J Exp Biol 1980;18(1):39
4-methylhistamine  36507-31-0 1H-imidazole-4-ethanamine, 5-methyl  *Methylhistamines Receptors, Histamine H2. Agents Actions 1980;10(1-2):167

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