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Receptors, Thyroid Hormone

More information in Books or onNLM PubMed
Definition: Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.  coord IM with specific thyroid hormone (IM); DF: RECEPT THYROID HORMONE   
See Also Thyroid Hormone Resistance Syndrome
Examples Thyroid Hormone Receptors alpha; Thyroid Hormone Receptors beta 		Other names Triiodothyronine Receptors; Thyroxine Receptors; Thyroid Hormone Receptors; T4 Receptors; T3 Receptors; Receptors, Triiodothyronine; Receptors, Thyroxine; Receptors, Diiodotyrosine; Diiodotyrosine Receptors; Thyroxine Receptor; Thyroid Hormone Receptor; T4 Receptor; T3 Receptor; Receptors, T4; Receptors, T3; Receptors, Monoiodotyrosine; Receptors, MIT; Receptors, DIT; Monoiodotyrosine Receptors; MIT Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
DOR protein, rat  0   *Muscle Proteins Receptors, Thyroid Hormone. PLoS ONE. 2007;2(11) (dup#9):e1183
3-(3,5-dibromo-4-(4-hydroxy-3-isopropyl-5-(2-pyridin-4-ylvinyl)phenoxy)phenyl)propionic acid  0   *Phenylpropionates *Pyridines Receptors, Thyroid Hormone/antagonists & inhibitors. J Med Chem 2006 Nov 16;49(23):6635-7
NR2C2 protein, human  0   *Receptors, Steroid *Receptors, Thyroid Hormone DNA-Binding Proteins Zinc Fingers.
Nr2c2 protein, mouse  0   *Receptors, Steroid *Receptors, Thyroid Hormone DNA-Binding Proteins Zinc Fingers.
NR4A3 protein, human  0   *DNA-Binding Proteins *Receptors, Steroid *Receptors, Thyroid Hormone.
Nr4a3 protein, mouse  0   *DNA-Binding Proteins *Nerve Tissue Proteins *Receptors, Steroid *Receptors, Thyroid Hormone.
KB 141  0   *Phenyl Ethers *Phenylacetates Receptors, Thyroid Hormone/agonists. Proc Natl Acad Sci U S A 2003 Aug 19;100(17):10067-72
3,5'-dibromo-4-(3',5'-diisopropyl-4'-hydroxyphenoxy)benzoic acid  0   *Benzoic Acids Receptors, Thyroid Hormone/antagonists & inhibitors. Endocrinology 2002 Feb;143(2):517-24
nuclear hormone receptor, Strongyloides stercoralis  0   *Receptors, Cytoplasmic and Nuclear Receptors, Steroid Receptors, Thyroid Hormone. Parasitol Res 2000 Jan;86(1):24-9
BRD8 protein, human  0   *Receptors, Thyroid Hormone. Biochim Biophys Acta 1996 Apr 10;1306(1):14-6
Tr4 protein, rat  0   *Receptors, Steroid *Receptors, Thyroid Hormone DNA-Binding Proteins Zinc Fingers. Gene Expr 1994;4(1-2):77-84; Mol Endocrinol 1994 Dec;8(12):1667-80
Nr4a3 protein, rat  0   *DNA-Binding Proteins *Nerve Tissue Proteins Receptors, Steroid Receptors, Thyroid Hormone. Biochem Biophys Res Commun 1994 Dec 30;205(3):1959-65; Hum Mol Genet 1995 Dec;4(12):2219-26
thyroid hormone receptor alpha B, flounder  0   *Receptors, Thyroid Hormone *Fish Proteins Zinc Fingers. Dev Genet 1994;15(4):378-82
thyroid hormone receptor alpha A, flounder  0   *Receptors, Thyroid Hormone *Fish Proteins Zinc Fingers. Dev Genet 1994;15(4):378-82
reverse T3 receptor  0   *Receptors, Thyroid Hormone Triiodothyronine, Reverse. J Recept Res 1983;3(3):393

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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