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Recombinant Fusion Proteins

More information in Books or onNLM PubMed
Definition: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.  do not confuse with MEMBRANE FUSION PROTEINS; VIRAL FUSION PROTEINS; MUTANT CHIMERIC PROTEINS; or ONCOGENE PROTEINS, FUSION   
See Also Immunotoxins
Examples CD4 Immunoadhesins 		Other names Fusion Proteins, Recombinant; Proteins, Recombinant Hybrid; Proteins, Recombinant Fusion; Proteins, Recombinant Chimeric; Recombinant Hybrid Proteins; Recombinant Chimeric Proteins; Hybrid Proteins, Recombinant; Chimeric Proteins, Recombinant
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Fzd8CRD  0   *Recombinant Fusion Proteins. Cancer Res. 2012 Mar 15;72(6):1568-78
SAK-RGD-K2-Hirul  EC 3.4.24.-   *Hirudins *Metalloendopeptidases *Recombinant Fusion Proteins. Acta Biochim Pol. 2009;56(1):41-53.
TuNEX protein  0   *Immunoglobulin G *Recombinant Fusion Proteins *Receptors, Tumor Necrosis Factor. J Chin Med Assoc. 2011 Dec;74(12):544-51.
Dll4-Fc protein  0   *Recombinant Fusion Proteins. Blood. 2011 Jul 28;118(4):1154-62.
sFLT01 fusion protein  0   *Recombinant Fusion Proteins. Mol Cancer Ther. 2011 Mar;10(3):404-15.
myelin oligodendrocyte glycoprotein-reovirus type 3 protein sigma 1 fusion protein  0   *Recombinant Fusion Proteins. Eur J Immunol. 2011 Feb;41(2):313-23.
RTL342M protein, mouse  0   *Recombinant Fusion Proteins Neuroprotective Agents. Invest Ophthalmol Vis Sci. 2012 Jan;53(1) (dup#4):406-12
Tat-ANX1 fusion protein  0   *Recombinant Fusion Proteins *Gene Products, tat *Annexins. Biochem Biophys Res Commun. 2012 Jan 20;417(3):1024-9.
asfotase alfa  0   *Alkaline Phosphatase *Immunoglobulin G *Recombinant Fusion Proteins Hypophosphatasia/drug therapy Enzyme Replacement Therapy. N Engl J Med. 2012 Mar 8;366(10):904-13
(Z(EGFR)-1907)2 affibody  0   *Recombinant Fusion Proteins. Int J Oncol. 2012 Jan;40(1):176-84.
PF 04603629  0   *Recombinant Fusion Proteins. Diabetes Obes Metab. 2011 Nov;13(11):1056-8.
3-(iodobenzoyl)norbiotinamide-PTD-ODD-SAV fusion protein  0   *Recombinant Fusion Proteins Biotin/*analogs & derivatives Iodine Radioisotopes. Cancer Sci. 2011 Nov;102(11):2090-6.
CDX 1307  0   *Recombinant Fusion Proteins *Cancer Vaccines Antibodies, Monoclonal Chorionic Gonadotropin, beta Subunit, Human. Clin Cancer Res. 2011 Jul 15;17(14):4844-53.
semaphorin 3A lytic peptide  0   *Semaphorins *Recombinant Fusion Proteins. Biochem Biophys Res Commun. 2011 Oct 14;414(1):60-6.
IL-15Ralpha-sushi domain-linker-IL-15 fusion protein  0   *Recombinant Fusion Proteins Interleukin-15 Interleukin-15 Receptor alpha Subunit. J Biol Chem. 2006 Jan 20;281(3):1612-9.
HER2 affitoxin  0   *Recombinant Fusion Proteins Immunotoxins. J Immunother. 2009 Oct;32(8):817-25.
TAT-mu utrophin fusion protein  0   *Recombinant Fusion Proteins Gene Products, tat Utrophin. J Appl Physiol. 2011 Jul;111(1):200-5.
PEP-1-heme oxygenase-1 fusion protein  EC 1.14.99.3   *Recombinant Fusion Proteins *Heme Oxygenase-1. Biochem Biophys Res Commun 2011 Jul 29;411(2):354-9
HOXA5-PTD-APE1-Ref-1 fusion protein, human  0   *Recombinant Fusion Proteins. Biochem Biophys Res Commun 2011 Jul 1;410(2):312-6
BSD352 peptide  0   *Recombinant Fusion Proteins. Anticancer Drugs 2011 mar;22(3):213-22
P11-hEGF fusion protein  0   *Recombinant Fusion Proteins. Int J Pharm 2011 Feb 28;405(1-2):1-8
Flt(1-3)-IgG  0   *Immunoglobulin G *Recombinant Fusion Proteins *Vascular Endothelial Growth Factor Receptor-1 Vascular Endothelial Growth Factor A/antagonists & inhibitors. Nat Med 1999 Jun;5(6):623-8
AS1409 protein  0   *Recombinant Fusion Proteins. Clin Cancer Res 2011 Apr 1;17(7):1998-2005
TAT-CAL-DEETGE peptide  0   *Recombinant Fusion Proteins. Biochem Biophys Res Commun 2011 Apr 15;407(3):501-6
L19mTNFalpha protein  0   *Recombinant Fusion Proteins. Clin Cancer Res 2011 Feb 1;17(3):447-58
MIT3 fusion protein  0   *Recombinant Fusion Proteins. Hepatology 1996 Jul;24(1):97-103
PEP-1-catalase fusion protein  EC 1.11.1.6   *Recombinant Fusion Proteins Catalase. Free Radic Biol Med 2009 Oct 1;47(7):941-52
Mega-Fas-ligand  0   *Recombinant Fusion Proteins. Neuro Oncol 2011 Feb;13(2):155-64
Atsttrin fusion protein  0   *Recombinant Fusion Proteins. Science 2011 Apr 22;332(6028):478-84
Ag85B-ESAT-6 fusion antigen  0   *Recombinant Fusion Proteins Tuberculosis Vaccines. Infect Immun 2001 May;69(5):2773-8
PTD4-apoptin protein  0   *Recombinant Fusion Proteins. Int J Cancer 2009 Jun 15;124(12):2973-81
FP3 VEGF receptor Fc-fusion protein  0   *Recombinant Fusion Proteins Vascular Endothelial Growth Factor A/antagonists & inhibitors. Cancer Immunol Immunother 2010 Feb;59(2):239-46
immunoRNase scFv 4D5-dibarnase  0   *Recombinant Fusion Proteins *Ribonucleases Single-Chain Antibodies. Invest New Drugs 2011 Feb;29(1):22-32
PTD-SARA fusion protein, human  0   *Recombinant Fusion Proteins. Acta Biochim Biophys Sin (Shanghai) 2010 Feb;43(2):110-7
maltose-binding protein-gonadotropin releasing hormone I fusion protein  0   *Recombinant Fusion Proteins. Sust Biol Reprod Med 2010 Dec;56(6):478-86
LY 2189265  0   *Immunoglobulin Fc Fragments *Recombinant Fusion Proteins Glucagon-Like Peptides Receptors, Glucagon. Diabetes Metab Res Rev. 2010 May;26(4):287-96
anti-CD20Fab-LDM protein  0   *Recombinant Fusion Proteins. Gene Ther 2010 Oct;17(10):1234-43
DrTx(1-42)  0   *Recombinant Fusion Proteins. Biochem Pharmacol. 2011 Feb 1;81(3):425-31
attacin-thanatin peptide  0   *Recombinant Fusion Proteins. Mol Biol Rep 2010 Oct;37(7):3495-501
L19-IL2 immunocytokine  0   *Recombinant Fusion Proteins. Blood 2002 Mar 1;99(5):1659-65
RTL220 protein  0   *Recombinant Fusion Proteins Ligands. Ophthalmic Res 2010;44(1):24-33
Boymaw-DISC1 fusion protein, human  0   *Recombinant Fusion Proteins. Mol Psychiatry 2010 Jul;15(7):669-72
DISC1-boymaw fusion protein, human  0   *Recombinant Fusion Proteins. Mol Psychiatry 2010 Jul;15(7):669-72
drosotoxin  0   *Recombinant Fusion Proteins. Biochem Pharmacol 2010 Oct 15;80(8):1296-302
PEGylated tumor necrosis factor-related apoptosis-inducing ligand  0   *Polyethylene Glycols *Recombinant Fusion Proteins. Mol Cancer Ther 2010 Jun;9(6):1719-29
Ebip protein  0   *Recombinant Fusion Proteins. Mol Cancer Ther 2010 Jun;9(6):1503-14
amyloid-beta(40-1)-Gly8-1-40 peptide  0   *Peptide Fragments *Amyloid beta-Peptides Recombinant Fusion Proteins. Biochem Biophys Res Commun 2010 Jul 2;397(3):509-12
AMG 386  0   *Recombinant Fusion Proteins. J Clin Oncol 2009 Jul 20;27(21):3557-65
GIFT12 protein  0   *Recombinant Fusion Proteins *Cytokines. Med Sci (Paris). 2010 Feb;26(2):137-9
TRU 016  0   *Immunoglobulin G *Recombinant Fusion Proteins. Curr Opin Investig Drugs 2009 Dec;10(12):1383-90
TAT-54R-KDEL protein  0   *Recombinant Fusion Proteins. Mol Cancer Res 2009 Oct;7(10):1613-21
AGT-181  0   *Antibodies, Monoclonal *Iduronidase *Recombinant Fusion Proteins. J Biotechnol. 2009 Oct 26;144(2):135-41
Bz-DOTA-ABD-(Z(HER2-342))2  0   *Recombinant Fusion Proteins. Eur J Nucl Med Mol Imaging 2009 Sep;36(9):1460-8
177Lu-CHX-A''-DTPA-ABD-(Z(HER2-342))2  0   *Organometallic Compounds *Recombinant Fusion Proteins Lutetium. Eur J Nucl Med Mol Imaging 2009 Sep;36(9):1460-8
TLR4 decoy  0   *Recombinant Fusion Proteins. PLoS One 2009;4(10):e7403
VB4-845  0   *Recombinant Fusion Proteins. Med Oncol. 2009;26(3):257-64
N(epsilon)49-mercaptoacetyl-glutamyl-seryl-glutamyl-ZHER2-342  0   *Recombinant Fusion Proteins. Bioorg Med Chem Lett 2009 Jul 15;19(14):3912-4
N(epsilon)49-mercaptoacetyl-seryl-seryl-seryl-ZHER2-342  0   *Recombinant Fusion Proteins. Bioorg Med Chem Lett 2009 Jul 15;19(14):3912-4
N(epsilon)49-mercaptoacetyl-glycyl-glycyl-glycyl-ZHER2-342  0   *Recombinant Fusion Proteins. Bioorg Med Chem Lett 2009 Jul 15;19(14):3912-4
DAPK2'-CD30L fusion protein  EC 2.7.1.-   *Recombinant Fusion Proteins. J Immunother 2009 Jun;32(5):431-41
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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