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Retinoids

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Definition: A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization.     
Examples Acitretin; Etretinate; Fenretinide; Isotretinoin; Retinaldehyde; Vitamin A
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
LG 100815  0   *Retinoids. J Neurochem 2008 Dec;107(5):1206-15
LG 101208  0   *Retinoids Retinoid X Receptor alpha/antagonists & inhibitors. J Neurochem 2008 Dec;107(5):1206-15
retinyl retinoate  0   *Retinoids. Bioorg Med Chem. 2008 Jun 15;16(12):6387-93
C22 aldehyde  0   *Retinoids. Mol Vis 2006;12:1699-705
BMS 961  0   *Retinoids. Nat Struct Biol 1998 Mar;5(3):199-202
A2-PE compound  0   *Pyridinium Compounds *Retinoids. Exp Eye Res 2006 May;82(5):828-39
retinyl ascorbate  0   *Retinoids Ascorbic Acid/*analogs & derivatives. Free Radic Res 2005 May;39(5):491-8
4-(5-(7-fluoro-4-(trifluoromethyl)benzo(b)furan-2-yl)-1H-2-pyrrolyl)benzoic acid  0   *Benzofurans *Pyrroles *Benzoic Acids Retinoids. J Pharmacol Exp Ther. 2005 Mar;312(3):938-944
N-retinylidene-phosphatidylethanolamine  0   *Phosphatidylethanolamines *Retinoids. J Biol Chem 2004 Dec 24;279(52):53972-9
4-hydroxy-retinol  0   Vitamin A/*analogs & derivatives Retinoids. Life Sci. 2005 Feb 18;76(14):1613-22
AGN 195183  0   *Retinoids. J Mol Med 2004 Feb;82(2):116-25
MDI 301  0   *Retinoids. Arch Dermatol Res 2003 Nov;295(6):255-62
(2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid  0   *Retinoids. Carcinogenesis. 2004 Jun;25(6):979-85
A2-rhodopsin  0   *Retinoids *Rhodopsin. Org Biomol Chem 2003 Apr 7;1(7):1101-5
4-amino-2-(butyrylamino)phenyl(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraenoate  0   *Retinoids. Int J Cancer. 2003 Dec 20;107(6):1038-46
BMS 649  0   *Retinoids. J Clin Endocrinol Metab 2000 Jul;85(7):2550-5
A2E compound  0   *Pyridinium Compounds *Retinoids. J Biol Chem 2002 Mar 1;277(9):7183-90
CD 666  0   *Retinoids. Arch Pharm Res 2001 Aug;24(4):744-50
3',5'-ditertiary-butiary-4'-methoxycarboxylchalcone  0   *Retinoids *Chalcones. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1998 Dec;20(6):459-65
acycloretinal  0   *Retinoids. Lipids 2001 Feb;36(2):191-9
acyclo-retinoic acid  0   *Retinoids. Arch Biochem Biophys 2000 Jan 1;373(1):271-4
hydroxenin monoacetate  0   *Retinoids. Ultrason Sonochem 2001 Jul;8(3):217-20
MM11453  0   *Retinoids. Cancer Res 2001 Jun 15;61(12):4723-30
Ro48 2250  0   *Retinoids. Oncogene 2001 Jan 18;20(3):375-84
BMS 189453  0   *Retinoids Receptors, Retinoic Acid/antagonists & inhibitors. Toxicol Sci 2001 Feb;59(2):297-308
MM 11365  0   *Retinoids. Int J Cancer. 2001 Jan 1;91(1):8-21
MM 11254  0   *Retinoids. Int J Cancer. 2001 Jan 1;91(1):8-21
CD 2394  0   *Benzoates *Retinoids. Acta Derm Venereol 2000 Mar-Apr;80(2):98-101
4-acetamidophenyl retinoate  0   *Retinoids. Chung Hua Chung Liu Tsa Chih 1997 May;19(3):196-9
Ro 23-9223  0   *Retinoids Tretinoin. Toxicol Appl Pharmacol 2000 Apr 15;164(2):71-5
Ro 16-9100  0   *Retinoids. Anticancer Res 2000 Jan-Feb;20(1A):27-32
LG10068  0   *Retinoids. J Natl Cancer Inst 2000 Mar 1;92(5):418-23
CD 2409  0   *Tetrahydronaphthalenes *Benzoic Acids Retinoids. J Biol Chem 2000 Jan 7;275(1):642-50
BMS453  0   *Retinoids Receptors, Retinoic Acid/antagonists & inhibitors. Breast Cancer Res Treat 1999 Aug;56(3):277-91
retinylidene chromophore  0   *Retinoids Retinal Pigments. Biochemistry 1999 Sep 7;38(36):11762-72
SR 11238  0   *Retinoids. Br J Cancer 1999 Jan;79(1):101-7
retinamidobenzyl glucuronide  0   *Glucuronates *Retinoids. Anticancer Res 1999 Mar-Apr;19(2A):999-1004
dihydroanthracenyl retinoid  0   *Anthracenes *Retinoids Receptors, Retinoic Acid/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Mar 8;9(5):743-8
benzothiochromenyl retinoid  0   *Retinoids Receptors, Retinoic Acid/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Mar 8;9(5):743-8
benzochromenyl retinoid  0   *Retinoids Receptors, Retinoic Acid/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Mar 8;9(5):743-8
3-hydroxyretinoic acid  0   *Retinoids. J Pharm Biomed Anal 1998 Dec;18(4-5):761-76
MX 781  0   *Ethers *Retinoids Retinoids/antagonists & inhibitors. Cancer Res 1998 Oct 15;58(20):4607-10
MX 84 ester  0   *Retinoids. J Biol Chem 1998 Aug 14;273(33):20852-9
4-(3-methyl-5-(2',6',6'-trimethyl-1'-cyclohex-1'-yl)pentadienamido)benzoic acid  0   *Benzoates *Cyclohexanes Retinoids. J Med Chem 1998 Jul 30;41(16):3062-77
4-(2-(5,6,7,8--tetrahydro-5,5,8,8-tetramethylquinoxalyl)carboxamido)benzoic acid  0   *Benzoates *Quinoxalines Retinoids. J Med Chem 1998 Jul 30;41(16):3062-77
A2-E (N-retinylidene-N-retinylethanolamine)  0   *Retinoids Retinal Pigments. Exp Eye Res 1997 Nov;65(5):639-43
LG 100629  0   *Retinoids Receptors, Retinoic Acid/antagonists & inhibitors. Proc Natl Acad Sci U S A 1992 Aug 1;89(15):7129-33
SR 11235  0   *Retinoids. Proc Natl Acad Sci U S A 1997 May 27;94(11):5826-30
SR 11302  0   *Retinoids. Proc Natl Acad Sci U S A 1997 May 27;94(11):5826-30
AGN 190727  0   *Retinoids. Fundam Appl Toxicol 1996 Oct;33(2):264-71
LE 550  0   *Dibenzazepines Retinoids/antagonists & inhibitors. Yakugaku Zasshi 1996 Dec;116(12):928-41
LE 540  0   *Dibenzazepines Retinoids/antagonists & inhibitors. Yakugaku Zasshi 1996 Dec;116(12):928-41
LE 135  0   *Dibenzazepines Retinoids/antagonists & inhibitors. Yakugaku Zasshi 1996 Dec;116(12):928-41
CD 2608  0   *Retinoids. Leukemia 1997 Feb;11(2):221-7
LG 100754  0   *Retinoids *Tetrahydronaphthalenes. Nature 1996 Oct 3;383(6599):450-3
CD 2019  0   *Naphthalenes Retinoids. Teratology 1996 Mar;53(3):158-67
ALRT 1550  0   *Retinoids Stereoisomerism Receptors, Retinoic Acid/agonists. J Med Chem 1996 Jul 5;39(14):2659-63
CD 437  0   *Retinoids.
Pharma Action Antineoplastic Agents 		Blood 1996 Mar 1;87(5):1939-50
CD 394  0   *Retinoids. Toxicol Lett 1995 Jan;75(1-3):159-68
ADAM 3  0   *Retinoids. Biochem Biophys Res Commun 1995 Feb 6;207(1):444-51
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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