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Ribavirin

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Definition: A nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses.     
Pharmacological Action Antimetabolites; Antiviral Agents 		Other names Tribavirin; Ribovirin; Ribavirin Merck Brand; ICN1229; ICN 1229; Virazole; Viramide; Three Rivers Pharmaceuticals Brand of Ribavirin; Virazide; Ribasphere; Ribamidyl; Ribamidil; Ribamide; Rebetol; Pfizer Brand of Ribavirin; Merck Brand of Ribavirin; ICN-1229; ICN Brand of Ribavirin; Grossman Brand of Ribavirin; Essex Brand of RibavirinDrugs* : VIRAZOLE; RIBAVIRIN; REBETOL; RIBAVARIN; COPEGUS; RIBASPHERE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tiazofurin monophosphate  0   Ribavirin/*analogs & derivatives. Biochemistry 2007 Apr 24;46(16):4912-22
2-(3-amino-3-deoxyxylofuranosyl)thiazole-4-carboxamide  0   *Thiazoles Ribavirin/*analogs & derivatives. Bioorg Med Chem Lett 2006 Oct 15;16(20):5317-20
5'-nor carbocyclic ribavirin  0   Ribavirin/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2003 Nov;22(11):1995-2001
Rebetron  0   *Ribavirin *Interferon-alpha Drug Combinations Hepatitis C/drug therapy. FDA Consum 1999 Mar-Apr;33(2):23-9
4-fluoro-1-ribofuranosyl-1H-pyrazole-3-carboxamide  0   Ribavirin/*analogs & derivatives. Nucleosides Nucleotides 1999 Feb;18(2):203-16
2',3'-didehydro-2',3'-dideoxytiazofurin  131922-30-0   Ribavirin/*analogs & derivatives. Acta Crystallogr C 1991;47(pt 6):1272
2',3'-dideoxytiazofurin  135355-98-5   Ribavirin/*analogs & derivatives. Acta Crystallogr C 1991;47(pt 6):1272
2-ribofuranosyl-1,2,3-triazole-4,5-dicarboxamide  123027-68-9   Ribavirin/*analogs & derivatives. Biochem Pharmacol 1990;39(3):455
3-ribofuranosyl-1,2,4-triazole-5-carboxamide  62404-64-2   Ribavirin/*analogs & derivatives. Biochem Pharmacol 1990;39(3):455
1-(5'-O-sulfamoyl-beta-D-ribofuranosyl)(1,2,4)triazole-3-carbonitrile  123124-30-1   Ribavirin/*analogs & derivatives. J Med Chem 1990;33(1):44
1-(5'-O-sulfamoyl-beta-ribofuranosyl)(1,2,4)triazole-3-thiocarboxamide  123124-29-8   Ribavirin/*analogs & derivatives. J Med Chem 1990;33(1):44
methyl 1-ribofuranosyl-1,2,4-triazole-3-carboxamidate  120362-25-6   Ribavirin/*analogs & derivatives. J Med Chem 1989;32(7):11147
ethyl 1-ribofuranosyl-1,2,4-triazole-3-carboximidate  120362-26-7   Ribavirin/*analogs & derivatives. J Med Chem 1989;32(7):1447
ribavirin 5'-sulfamate  120615-22-7 1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-(aminosulfonyl)-beta-D-ribofuranosyl)  Ribavirin/*analogs & derivatives. Antiviral Res 1988;10(6):253
ribavirin 5'-diphosphate  63142-70-1   Ribavirin/*analogs & derivatives. Antimicrob Agents Chemother 1988;32(4):492
5'-O-galactopyranosyl ribavirin  114283-62-4   Ribavirin/*analogs & derivatives. Carbohydr Res 1987;165(2);267
5'-O-glucopyranosyl ribavirin  114283-60-2   Ribavirin/*analogs & derivatives. Carbohydr Res 1987;165(2):267
tributylribavirin  101843-94-1   Ribavirin/*analogs & derivatives. Antimicrob Agents Chemother 1986;29(3):521
ribavirin 2',3',5'-triacetate  40372-03-0   Ribavirin/*analogs & derivatives. Antimicrob Agents Chemother 1983;24(1):134
adenylyl-(3'-5')-virazole  80948-57-8 3'-Adenylic acid, 3'-5'-ester with 1-beta-D-ribofuranosyl-1H-1,2,4-triazole-3-carboxamide  Adenosine Monophosphate/*analogs & derivatives Ribavirin/*analogs & derivatives. Vopr Virusol 1982;27(5):104
tiazofurin  60084-10-8   Ribavirin/*analogs & derivatives.
Pharma Action Antimetabolites, Antineoplastic ; Antineoplastic Agents 		J Med Chem 1982;25(2):107
ribavirin amidine  40372-00-7   Ribavirin/*analogs & derivatives Purine-Nucleoside Phosphorylase/antagonists & inhibitors. Mol Pharmacol 1980;18(2):287
1-(4-thio-beta-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide  58928-39-5   Ribavirin/*analogs & derivatives. J Med Chem 19(6):841;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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