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Salicylates

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Definition: The salts, esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.     
Pharmacological Action Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors
Examples Gentisates; Sodium Salicylate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methyl 2-O-(4-O-beta-D-galactopyranosyl)-beta-D-glucopyranosylbenzoate  0   *Disaccharides *Salicylates. J Asian Nat Prod Res. 2011 Sep;13(9):817-25
4-nitrophenyl salicylate  0   *Nitrophenols *Salicylates. Chemistry. 2011 Mar 1;17(10):3021-7
paucinervin B  0   *Salicylates. Bioorg Med Chem 2010 Jul 15;18(14):4957-64
N,N'-(3,4-diaminobenzophenon)-3,5-Bu(t)(2)-salicylaldimine  0   *Benzophenones *Salicylates. Spectrochim Acta A Mol Biomol Spectrosc. 2010 Feb;75(2):811-8
isodivaricatic acid  0   *Salicylates. Phytother Res 2008 Mar;22(3):349-55
salicylideneamino-2-thiophenol  0   *Salicylates *Sulfhydryl Compounds. Biotechnol Lett 2008 Sep;30(9):1553-8
methyl salicylate 2-O-beta-D-glucoside  0   *Glucosides *Salicylates. Phytochemistry 2008 Mar;69(5):1128-34
Holisal  0   *Salicylates Cellulose/*analogs & derivatives Choline/*analogs & derivatives Glycerol/*analogs & derivatives. Georgian Med News 2008 Jan;(154):36-9
N-(3,5-di-tert-butylsalicylidene)-1-ethylcarboxylato-4-aminopiperidine  0   *Piperidines *Salicylates. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Nov;68(3):463-8
phenethyl salicylate  0   *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S467-71
pentyl salicylate  0   *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S460-6
methyl 4-methylsalicylate  0   *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S457-9
3-methyl-2-butenyl salicylate  0   *Butanes *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S453-6
isobutyl salicylate  0   *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S410-7
hexyl salicylate  0   *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S410-7
1,3-dimethyl-3-butenyl salicylate  0   *Butanes *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S389-92
p-cresyl salicylate  0   *Cresols *Salicylates. Food Chem Toxicol. 2007;45 Suppl 1():S385-8
1-((nonyloxy)methyl)-1H-imidazol-3-ium salicylate  0   *Imidazoles *Salicylates. Chem Biodivers 2007 Sep;4(9):2218-24
3-isopropylsalicylic acid  0   *Salicylates. Eur J Pharm Sci 2007 Aug;31(5):306-17
salaceyin B  0   *Salicylates. J Antibiot (Tokyo) 2006 Dec;59(12):797-800
salaceyin A  0   *Salicylates. J Antibiot (Tokyo) 2006 Dec;59(12):797-800
wintergreen oil  68917-75-9   *Oils, Volatile *Plant Extracts Salicylates Betula Gaultheria.
olivetoric acid  0   *Salicylates. Z Naturforsch (C) 2006 Jul-Aug;61(7-8):499-507
calcium salicylate  0   *Salicylates. Cell Prolif. 2006 Aug;39(4):249-60
trifluoroethyl salicylate  0   *Salicylates. Biotechnol Prog 2006 Jan-Feb;22(1):331-3
2-((6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy) benzoic acid methyl ester  0   *Disaccharides *Salicylates. Eur J Pharmacol. 2006 Jan 13;530(1-2):166-71
3-methylsalicylic acid  0   *Salicylates. Appl Biochem Biotechnol 2005 Mar;120(3):183-98
Bismuth Salicylate  0   *Salicylates.
Magnesium Salicylate  0   *Salicylates.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Cyclooxygenase Inhibitors
butyl salicylate  0   *Salicylates. Eur J Pharm Sci 2004 Feb;21(2-3):379-88
N-salicyloyltryptamine  0   *Salicylates *Tryptamines. Br J Pharmacol 2003 Dec;140(7):1331-9
lobatamide D  0   *Salicylates *Macrolides. Org Lett 2004 Feb 19;6(4):577-80
lobatamide A  0   *Salicylates *Macrolides. Org Lett 2004 Feb 19;6(4):577-80
trimesoyl tris(dibromosalicylate)  0   *Salicylates. J Am Chem Soc. 2003 May 21;125(20):6070-1
lobatamide C  0   *Salicylates *Macrolides. J Am Chem Soc 2002 May 22;124(20):5650-1
EUK-189  0   *Organometallic Compounds *Salicylates Catalase. Exp Neurol 2001 Sep;171(1):84-97
EUK-134  0   *Organometallic Compounds *Salicylates Antioxidants Manganese Compounds. Bioorg Med Chem Lett 2001 Jun 4;11(11):1367-79
triphenyltin salicylate  0   *Organotin Compounds *Salicylates Pyrophosphatases. J Enzyme Inhib 2000 Jun;15(4):411-20
methyl 6-methylsalicylate  0   *Salicylates. Naturwissenschaften 2000 Jul;87(7):320-2
2-hydroxybenzoic acid 3-nitrooxymethylphenyl ester  0   *Nitrates *Salicylates. Bioorg Med Chem Lett 2000 May 15;10(10):350-3
1-(5'-bromosalicylidene)-2-(2''-pyridyl)hydrazine  0   *Hydrazines *Salicylates. Biochem Pharmacol 2000 Aug 15;60(4):581-7
valerylsalicylate  0   *Salicylates. Am J Physiol 1999 Nov;277(5 Pt 2):F706-F710
methacryloyloxyethyl 5-aminosalicylate  0   *Methacrylates *Salicylates. J Controlled Release 1999 Apr 19;58(3):279-87
N-(4-(1-hydroxy-2-(dibutylamino)ethyl)quinolin-8-yl)-4-azidosalicylamide  0   *Quinolines *Salicylates. Biochem Biophys Res Commun 1997 Dec 8;241(1):104-11
S-(4-nitrobenzyl)glutathione-iodo-4-azidosalicyclic acid  0   *Salicylates Glutathione/*analogs & derivatives Iodine Radioisotopes. J Biol Chem 1997 Apr 18;272(16):10936-40
leukotriene C4-iodo-4-azidosalicylic acid  0   *Salicylates Leukotriene C4/*analogs & derivatives Iodine Radioisotopes. J Biol Chem 1997 Apr 18;272(16):10936-40
tris(3,5-dibromosalicyl) tricarballylate  137656-90-7   *Salicylates *Tricarboxylic Acids. Artif Cells Blood Substit Immobil Biotechnol 1996 Nov;24(6):587-98
2-ethylhexyl salicylate  118-60-5   *Salicylates Sunscreening Agents. J Chromatogr B Biomed Appl 1996 Jun 28;682(1):137-45
orbuticin  0   Salicylates. J Antibiot (Tokyo) 1996 Nov;49(11):1186-7
S-(2-(4-azidisalicylamido)ethylthio)-2-thiopyridine  0   *Pyridines *Salicylates. Bioconjug Chem 1996 May-Jun;7(3):380-4
Lavoris Mouthwash  0   *Eugenol *Furaldehyde *Salicylates Drug Combinations. Oper Dent 1995 Jan-Feb;20(1):14-7
2-acetamido-5-(3-(4-azido-3-iodosalicylamido)phenoxy)benzimidazole  0   *Benzimidazoles *Salicylates Iodine Radioisotopes. J Biol Chem 1996 Apr 12;271(15):8575-81
salicylic acid maltol ester  0   *Salicylates. Arzneimittelforschung 1995 Oct;45(10):1071-4
12-((5-iodo-4-azidosalicyl)amino)dodecanoyl-coenzyme A  0   *Acyl Coenzyme A *Salicylates. FEBS Lett 1995 Nov 20;375(3):188-92
confluentic acid  6009-12-7   *Benzoates *Salicylates *Depsides. Chem Pharm Bull (Tokyo) 1994 Jun;42(6):1198-201
2'-O-methylperlatolic acid  38968-07-9   *Benzoates *Salicylates *Depsides. Chem Pharm Bull (Tokyo) 1994 Jun;42(6):1198-201
aquastatin A  153821-50-2   *Galactosides *Salicylates. J Antibiot (Tokyo) 1993 Nov;46(11):1648-57
benorilate  5003-48-5 Benzoic acid, 2-(acetyloxy)-, 4-(acetylamino)phenyl ester  *Acetanilides *Salicylates.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal
triphenyltin 3,5-diisopropylsalicylate  143716-16-9 Phenol, 2,4-bis(1-methylethyl)-6-(((triphenylstannyl)oxy)carbonyl)  *Organotin Compounds *Salicylates. In Vivo 1993 Mar-Apr;7(2):171-4
choline salicylate, glycerol drug combination  0   *Salicylates *Glycerol Drug Combinations. Curr Med Res Opin 1992;13(1):21-5
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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