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Sulfasalazine

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Definition: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)     
Pharmacological Action Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Gastrointestinal Agents 		Other names Salicylazosulfapyridine; ratio Sulfasalazine; Sulfasalazine Pfizer Brand; Sulfasalazin Heyl; EN, Azulfidine; Colo Pleon; ratio-Sulfasalazine; medac Brand of Sulfasalazine; Ulcol; Ucine; Sulphasalazine; Sulfasalazine FNA; Sulfasalazin-Heyl; Sulfasalazin medac; Sanofi Synthelabo Brand of Sulfasalazine; Salazosulfapyridine; Salazopyrin; Ratiopharm Brand of Sulfasalazine; Pyralin EN; PleonDrugs* : AZULFIDINE EN-TABS; SULFASALAZINE; AZULFIDINE; S.A.S.-500
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
susalimod  0   *Benzoic Acids Sulfasalazine/*analogs & derivatives. J Pharm Pharmacol 1999 Jan;51(1):61-6
Salazopyrine  31363-03-8   *Sulfasalazine Drug Combinations Glucosamine/*analogs & derivatives. Union Med Can 1980;109(9):1326
homosulphasalazine  73536-01-3 Benzeneacetic acid, 2-hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)  Sulfasalazine/*analogs & derivatives. Eur J Pharmacol 1980;61(3):287
methylsulfasalazine  42753-53-7 2-hydroxy-5-((4-(((3-methyl-2-pyridinyl)amino)sulfonyl)phenyl)azo)benzoic acid  Sulfasalazine/*analogs & derivatives. Scan J Gastroenterol 14(6):647;1979
salicylazoiminopyridine  66030-25-9   Sulfasalazine/*analogs & derivatives. Anal Chim Acta 96(2):293;1978
salazodimethoxine  40016-88-4   Sulfasalazine/*analogs & derivatives. Farmatsiia 24(5):91;1975
salazodin  22933-72-8   Sulfasalazine/*analogs & derivatives. Farmatsiia 28(1):74;1979; Klin Med (Mosk) 56(3):87;1978; Sov Med (2):68;1979; Veterinariia 12:75;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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