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Sapogenins

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Definition: The aglucon moiety of a saponin molecule. It may be triterpenoid or steroid, usually spirostan, in nature.     
Examples Oleanolic Acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
21-nor-18,27-dimethyl-1,2,3-trihydroxy-25-spirost-4-en-19-oic acid  0   *Spirostans Sapogenins. Steroids 2011 Mar;76(4):358-64
20-methoxyldammarane-3,12,25-triol  0   *Sapogenins. Bioorg Med Chem Lett 2011 Feb 1;21(3):1027-31
25-methoxyldammarane-3,12,20-triol  0   *Sapogenins. Bioorg Med Chem Lett 2011 Feb 1;21(3):1027-31
23-oxotigogenin acetate  0   *Sapogenins. Steroids 2009 Aug;74(8):675-83
esculeoside A  0   *Sapogenins. Chem Pharm Bull (Tokyo). 2008 Jul;56(7):926-9
atroviolaceoside  0   *Glycosides *Sapogenins. J Nat Prod 2006 Feb;69(2):191-5
atroviolacegenin  0   *Sapogenins. J Nat Prod 2006 Feb;69(2):191-5
ginsenoside 20S-protopanaxatriol  0   *Sapogenins *Ginsenosides. Biol Pharm Bull 2006 Jan;29(1):110-3
isoesculeogenin A  0   *Sapogenins. Chem Pharm Bull (Tokyo). 2005 Jul;53(7):839-40
esculeogenin B  0   *Sapogenins. Chem Pharm Bull (Tokyo). 2005 Jul;53(7):839-40
20-O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol  0   *Sapogenins. Toxicol Appl Pharmacol. 2004 Feb 1;194(3):221-9
saikogenin F  0   *Sapogenins. Zhongguo Zhong Yao Za Zhi 1998 Feb;23(2):96-8, 128
namogenin B  0   *Sapogenins *Spirostans. J Nat Prod 2001 Sep;64(9):1127-32
namogenin C  0   *Sapogenins *Spirostans. J Nat Prod 2001 Sep;64(9):1127-32
namogenin A  0   *Sapogenins *Spirostans. J Nat Prod 2001 Sep;64(9):1127-32
tupichigenin C  0   *Sapogenins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Sep;48(9):1350-3
tupichigenin B  0   *Sapogenins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Sep;48(9):1350-3
tupichigenin A  0   *Sapogenins *Sterols. J Nat Prod 2000 Jun;63(6):861-3
22-O-angeloyl theasapogenol E  0   *Sapogenins Drugs, Chinese Herbal. Chung Kuo Chung Yao Tsa Chih 1997 Apr;22(4):228-30, 254
prosaikogenin A  0   *Sapogenins. BiolPharmBull1998Jun;21(6):588-93
muzanzagenin  0   *Sapogenins. J Nat Prod 1997 Oct;60(10):1017-22
porrigenin B  0   *Sapogenins. J Nat Prod 1997 Oct;60(10):1003-7
porrigenin A  0   *Sapogenins. J Nat Prod 1997 Oct;60(10):1003-7
protopanaxatriol  34080-08-5   *Sapogenins Panax. Anal Biochem 1993 May 1;210(2):411-7
epismilagenin glucuronide  0   *Glucuronates *Spirostans Sapogenins. Aust Vet J 1992 Feb;69(2):34
glyyunnansapogenin F  139163-14-7   *Sapogenins Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(10):750
glyyunnanprosapogenin D  139163-13-6   *Sapogenins Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(10):750
glyyunnansapogenin B  131177-50-9 Olean-12-en-29-oic acid, 3,21,23-trihydroxy-, (3beta,4beta,20beta,21alpha)  *Sapogenins. Yao Hsueh Hsueh Pao 1990;25(7):515
glyyunnansapogenin A  131137-98-9 Olean-12-en-29-oic acid, 3,23-dihydroxy-16-oxo-, (3beta,4beta,20alpha)  *Sapogenins. Yao Hsueh Hsueh Pao 1990;25(7):515
protopanaxadiol  7755-01-3   *Sapogenins Antidepressive Agents Panax. Yao Hsueh Hsueh Pao 1989;24(11):877
cycloastragenol  84605-18-5 9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-, (3beta,6alpha,16beta,24R)  *Sapogenins Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1988;23(11):873
sarsasapogenin  82597-74-8   *Spirostans Drugs, Chinese Herbal Sapogenins Saponins. Yao Hsueh Hsueh Pao 1985;20(2):143
sarsasapogenone  512-07-2   *Spirostans Sapogenins. Yao Hsueh Hsueh Pao 1985;20(2):143
rockogenin  16653-52-4   *Spirostans Sapogenins. J Nat Prod 40(2):218;1977
ruscogenin  472-11-7 (1 beta,3 beta,25R)-spirost-5-ene-1,3-diol  *Spirostans Sapogenins. Muench Med Wochenschr 118(11):339;1976; Pharmazie 31(9):611;1976
holotoxinogenin  23519-00-8 3 beta,20 epsilon,25-trihydroxy-16-oxolanost-9(11)- ene-18-carboxylic acid lactone  *Sapogenins Holothurin Sea Cucumbers. J Org Chem 40(4):466;1975
hecogenin  467-55-0 (22R,25R)-3 beta-hydroxy-5 alpha-spirostan-12-one  *Sapogenins. J Natural Prod 40(2):218;1977; Steroids 31(5):661;1978
dihydromarthasterone  34218-94-5 Cholest-9(11)-en-23-one, 3,6-dihydroxy-, (3beta,5alpha,6alpha)  *Cholestenones Sapogenins. J Chem Soc (Perkin I) 16:1745;1973
holostanol  34437-55-3   *Sapogenins Toxins, Biological. Toxicon 9(4):319;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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