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Saxitoxin

More information in Books or onNLM PubMed
Definition: A compound that contains a reduced purine ring system but is not biosynthetically related to the purine alkaloids. It is a poison found in certain edible mollusks at certain times; elaborated by GONYAULAX and consumed by mollusks, fishes, etc. without ill effects. It is neurotoxic and causes RESPIRATORY PARALYSIS and other effects in MAMMALS, known as paralytic SHELLFISH poisoning.  /antag permitted but consider also ANTITOXINS   
Pharmacological Action Poisons 		Other names Gonyaulax Toxin; Toxin, Gonyaulax; Saxitonin; Mitilotoxin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
zetekitoxin AB  0   Saxitoxin/*analogs & derivatives. Proc Natl Acad Sci U S A 2004 Mar 30;101(13):4346-51
carbamoyl N-methylsaxitoxin  0   Saxitoxin/*analogs & derivatives Marine Toxins. Toxicon 1998 Apr;36(4):627-30
saxitoxinol  75420-34-7   Saxitoxin/*analogs & derivatives Tritium. Toxicon 1993 Jul;31(7):905-8
decarbamoyloxysaxitoxin  143084-69-9 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2,6-diamino-3a,4,8,9-tetrahydro-4-methyl-, (3aS-(3aalpha,4alpha,10aR*))  Saxitoxin/*analogs & derivatives. Toxicon 1992 May-Jun;30(5-6):645-52
decarbamoylneosaxitoxin  68683-58-9   Saxitoxin/*analogs & derivatives. Toxicon 1992 May-Jun;30(5-6):645-52
11-hydroxysaxitoxin sulfate  125604-84-4   Saxitoxin/*analogs & derivatives. Dokl Akad Nauk SSSR 1989;309(4):974
gonyautoxin II  60508-89-6   Saxitoxin/*analogs & derivatives Marine Toxins. J Gen Physiol 1984;84(2):281
gonyautoxin V  64296-25-9   Saxitoxin/*analogs & derivatives Marine Toxins. Fortschr Chem Org Naturst 1984;45:235
gonyautoxin I  60748-39-2   Saxitoxin/*analogs & derivatives Marine Toxins. Fortschr Chem Org Naturst 1984;45:235
gonyautoxin VIII  80226-62-6   Saxitoxin/*analogs & derivatives Marine Toxins. Fortschr Chem Org Naturst 1984;45:235
gonyautoxin VI  82810-44-4   Saxitoxin/*analogs & derivatives Marine Toxins. Fortschr Chem Org Naturst 1984;45:235
decarbamylsaxitoxin  58911-04-9   Saxitoxin/*analogs & derivatives. J Physiol (Lond) 1982;323:619
neosaxitoxin  64296-20-4   Saxitoxin/*analogs & derivatives.
Pharma Action Insecticides ; Neuromuscular Blocking Agents 		J Physiol (Lond) 1982;323:619
gonyautoxins  77462-64-7 Gonyautoxin  Saxitoxin/*analogs & derivatives Dinoflagellida Marine Toxins. J Am Chem Soc 98(17):5414;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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