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Scleroderma, Systemic

More information in Books or onNLM PubMed
Definition: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.  note specific indentations and SCLERODERMA, LOCALIZED   
Examples Scleroderma, Diffuse; Scleroderma, Limited
Other names Sclerosis, Systemic; Systemic Sclerosis; Systemic Scleroderma
 
SubstanceCAS Registry & nameCategoriesSource
Juvenile-onset scleroderma  0   Scleroderma, Localized Scleroderma, Systemic.
Juvenile systemic scleroderma  0   *Scleroderma, Systemic.
Wa antigen  0   *Autoantigens Scleroderma, Systemic. J Rheumatol 1991;18(3):373
Scl 70 antigen, human  0   *Nuclear Proteins Autoantigens Scleroderma, Systemic. Med Clin North Am 1986;70(2):237

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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