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Solanaceous Alkaloids

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Definition: Alkaloids, mainly tropanes, elaborated by plants of the family Solanaceae, including Atropa, Hyoscyamus, Mandragora, Nicotiana, Solanum, etc. Some act as cholinergic antagonists; most are very toxic; many are used medicinally.     
See Also Parasympatholytics
Examples Belladonna Alkaloids; Capsaicin; Nicotine; Solanine; Tomatine 		Other names Solanum Alkaloids; Alkaloids, Solanum; Alkaloids, Solanaceous
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
spirosol-5-en-3-yl acetate  0   *Phytosterols *Solanaceous Alkaloids. Chem Biodivers 2007 Jan;4(1):25-31
spirosolan-3-ol  0   *Phytosterols *Solanaceous Alkaloids. Chem Biodivers 2007 Jan;4(1):25-31
coramsine  0   *Solanaceous Alkaloids. J Immunother 2006 Mar-Apr;29(2):134-42
solaculine A  0   *Oligosaccharides *Solanaceous Alkaloids. Phytochemistry 2002 Jan;59(1):79-84
leptine I  0   *Solanaceous Alkaloids. Prep Biochem Biotechnol 2000 May;30(2);133-44
solsodomine B  0   *Solanaceous Alkaloids. J Nat Prod 1998 Jun 26;61(6):848-50
solsodomine A  0   *Solanaceous Alkaloids. J Nat Prod 1998 Jun 26;61(6):848-50
calystegine A3  0   *Nortropanes *Solanaceous Alkaloids beta-Glucosidase/antagonists & inhibitors. Glycobiology 1997 Dec;7(8):1085-8
calystegine B1  127414-86-2   *Nortropanes *Solanaceous Alkaloids beta-Glucosidase/antagonists & inhibitors. Glycobiology 1997 Dec;7(8):1085-8
calystegine C1  0   *Nortropanes *Solanaceous Alkaloids beta-Glucosidase/antagonists & inhibitors. Glycobiology 1997 Dec;7(8):1085-8
khasianine  32449-98-2   *Phytosterols *Solanaceous Alkaloids. Biochem Biophys Res Commun 1998 Jan 6;242(1):21-5
N-methylcalystegine A(3)  0   *Solanaceous Alkaloids *Tropanes alpha-Galactosidase/antagonists & inhibitors. Eur J Biochem 1997 Sep 1;248(2):296-303
N-methylcalystegine B3  0   *Solanaceous Alkaloids *Tropanes alpha-Galactosidase/antagonists & inhibitors Stereoisomerism. Eur J Biochem 1997 Sep 1;248(2):296-303
calystegine B(2)  127414-85-1   *Nortropanes *Solanaceous Alkaloids Glycoside Hydrolases/antagonists & inhibitors Trehalase/antagonists & inhibitors. J Nat Prod 1995 Jun;58(6):878-86
3-aminospirosolane  0   *Phytosterols *Solanaceous Alkaloids. J Nat Prod 1995 Apr;58(4):625-8
3-amino-5-spirosolene  0   *Phytosterols *Solanaceous Alkaloids. J Nat Prod 1995 Apr;58(4):625-8
isoanguivine  0   *Phytosterols *Solanaceous Alkaloids. Phytochemistry 1994 Dec;37(6):1725-7
anguivine  0   *Phytosterols *Solanaceous Alkaloids. Phytochemistry 1994 Dec;37(6):1725-7
conioidine B  154887-99-7   *Pyrrolidines *Solanaceous Alkaloids. J Nat Prod 1993 May;56(5):708-13
conioidine A  154887-98-6   *Pyrrolidines *Solanaceous Alkaloids. J Nat Prod 1993 May;56(5):708-13
incanumine  128585-03-5 beta-D-Glucopyranoside, (3beta, 22alpha,25R)-spirosol-5-en-3-yl O-beta-D-xylopyranosyl-(1-3)-O-(O-beta-D-xylopyranosyl-(1-4)-6-deoxy-alpha-L-mannopyranosyl-(1-4))  *Solanaceous Alkaloids Cytotoxins. J Nat Prod 1990;53(2):513
25-isosolafloridine  36297-66-2   *Solanaceous Alkaloids. J Ethnopharmacol 1988;24(2-3):155
isocapsicastrine  123164-25-0   *Solanaceous Alkaloids. Planta Med 1989;55(1):48
capsimine  123123-41-1   *Solanaceous Alkaloids. Planta Med 1989;55(1):48
neohyacinthoside  115491-59-3 beta-D-Glucopyranoside, (3beta)-solanid-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(O-beta-D-glucopyranosyl-(1-6)-O-beta-D-glucopyranosyl-(1-3)-beta-D-glucopyranosyl-(1-4))  *Solanaceous Alkaloids Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1988;23(1):61
hyacinthoside  102728-60-9 beta-D-Glucopyranoside, (3 beta)-solanid-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(O-beta-D-glucopyranosyl-(1-3)-beta-D-glucopyranosyl-(1-4))  *Glycosides *Solanaceous Alkaloids. Yao Hsueh Hsueh Pao 1986;21(3):177
beta-solamarine  3671-38-3   *Solanaceous Alkaloids. CRC Crit Rev Food Nutr 1980;12(4):371
alpha-solamargine  20318-30-3   *Solanaceous Alkaloids Stereoisomerism. CRC Crit Rev Food Sci Nutr 1980; 12(4):371
etiolin  36067-58-0   *Solanaceous Alkaloids. Pharmazie 32(8/9):537;1977
demissidine  474-08-8 (3 beta,5 alpha)-solanidan-3-ol  *Solanaceous Alkaloids. J Agric Food Chem 25(4):955;1977; J Steroid Biochem 8(4):311;1977
dihydroxyphysalin B  62857-87-8 16,24-Cyclo-13,14-secoergost-2-ene-18,26-dioic acid, 14,17:14,27-diepoxy-?,?,13,20,22-pentahydroxy-1,15-dioxo-, gamma-lactone delta-lactone, (14alpha,16beta,22alpha,25S)  *Solanaceous Alkaloids. Lloydia 39(6):405;1977
solacasine  59957-97-0 (3 beta,5 alpha,16 alpha,25 beta)-16,23-epoxy-23- methoxy-16,28-secosolanid-22(28)-en-3-amine  *Solanaceous Alkaloids. Experientia 32(4):415;1976
solasodine  126-17-0   *Solanaceous Alkaloids. Arzneim Forsch 26(1):55;1976; J Chromatogr 119:223;1976; J Pharm Sci 66(5):699;1977; J Pharm Sci 67(8):1169;1978; Pharmazie 32(8/9):537;1977; Planta Med 29(1):66;1976; Res Commun Chem Pathol Pharmacol 13(4):723;1976
anisodamine  55869-99-3 alpha-(hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester  *Solanaceous Alkaloids Drugs, Chinese Herbal.
Pharma Action Adrenergic alpha-Agonists ; Anti-Arrhythmia Agents ; Anti-Inflammatory Agents, Non-Steroidal ; Anti-Ulcer Agents ; Parasympatholytics ; Vasodilator Agents ; Free Radical Scavengers 		Chinese Med J 1(2):127;1975; Chinese Med J 1(3):216;1975; Chinese Med J 3(1):63;1977; Chinese Med J 5(0):58;1973; Naturwissenschaften 62(2):97;1975; Yao Hsueh Hsueh Pao 1979;14(4):208

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