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Somatomedins

More information in Books or onNLM PubMed
Definition: Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.     
See Also Receptors, Somatomedin
Examples Insulin-Like Growth Factor I; Insulin-Like Growth Factor II 		Other names Sulfation Factor; Insulin-Like Growth Factors; Growth Factors, Insulin-Like; Factors, Insulin-Like Growth; Factor, Sulfation; Somatomedin; Insulin Like Growth Factors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
insulin-like growth factor 3, zebrafish  0   *Somatomedins *Zebrafish Proteins. Biol Reprod 2011 Mar;84(3):476-86
Dilp6 protein, Drosophila  0   *Somatomedins *Drosophila Proteins. Dev Cell 2009 Dec;17(6):874-84
IGF1RB protein, zebrafish  0   *Somatomedins *Zebrafish Proteins. Endocrinology 2002 May;143(5):1858-71
IGF1RA protein, zebrafish  0   *Somatomedins *Zebrafish Proteins. Endocrinology 2002 May;143(5):1858-71
zea-mays insulin-like growth factor  0   *Somatomedins. Biochem J 2001 Aug 15;358(Pt 1):95-100
igf1 protein, zebrafish  0   *Somatomedins *Zebrafish Proteins. Gene 2001 May 2;268(1-2):67-75
Biomin H  0   *Somatomedins. Cas Lek Cesk 1994 Apr 4;133(7):213-4
insulin-like growth factor binding protein, acid labile subunit  0   *Carrier Proteins *Glycoproteins Somatomedins. Mol Endocrinol 1992 Jun;6(6):870-6
preproinsulin-like growth factor  135685-93-7   *Protein Precursors *Somatomedins. J Biol Chem 1990;266(4):2397
somatomedin inhibitor  0   *Somatomedins. Diabetes 28(10):919;1979
somatomedin B  63774-77-6   *Somatomedins.
Pharma Action Trypsin Inhibitors 		FEBS Lett 87(1):55;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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