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Sphingosine

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Definition: An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)     
See Also Sphingolipids
Examples Psychosine 		Other names 4 Sphingenine; 4-Sphingenine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-deoxymethylsphinganine  0   Sphingosine/*analogs & derivatives Biological Markers. Hum Mutat 2011 Jun;32(6):E2211-25
1-deoxysphinganine  0   Sphingosine/*analogs & derivatives Biological Markers. Hum Mutat 2011 Jun;32(6):E2211-25
OSU-2S  0   *Propylene Glycols Sphingosine/*analogs & derivatives. Hepatology. 2011 Jun;53(6):1943-58
2-amino-3,5-dihydroxyoctadecane  0   Sphingosine/*analogs & derivatives. Mol Cancer Ther 2011 Apr;10(4):648-57
3,4,5-trideuterio-d-erythro-sphingosine  0   Sphingosine/*analogs & derivatives. Chem Phys Lipids. 2010 Nov;163(8):809-13
RY221B-a  0   Sphingosine/*analogs & derivatives 2,2'-Dipyridyl/*analogs & derivatives Sphingomyelin Phosphodiesterase/antagonists & inhibitors. Bioorg Med Chem Lett 2010 Jul 1;20(13):3868-71
penasin B  0   Sphingosine/*analogs & derivatives. J Nat Prod. 2010 Nov 29;73(11):1947-50
penasin A  0   Sphingosine/*analogs & derivatives. J Nat Prod. 2010 Nov 29;73(11):1947-50
pecipamide  0   Sphingosine/*analogs & derivatives. Lipids. 2010 May;45(5):457-61
N-monomethylphytosphingosine  0   Sphingosine/*analogs & derivatives. Leuk Lymphoma 2010 Jan;51(5):132-45
ascotricin B  0   Sphingosine/*analogs & derivatives. J Antibiot (Tokyo). 2009 Jul;62(7):359-64
ascotricin A  0   Sphingosine/*analogs & derivatives. J Antibiot (Tokyo). 2009 Jul;62(7):359-64
FTY720-(E)-vinylphosphonate  0   *Vinyl Compounds Sphingosine/*analogs & derivatives Phosphonic Acids. J Org Chem. 2009 Apr 17;74(8):3192-5
N,N-dimethylphytosphingosine  0   Sphingosine/*analogs & derivatives. Toxicol Appl Pharmacol. 2009 Aug 15;239(1):87-97
N-(5-(5,7-dimethyl Bodipy)-1-pentanoyl)-erythrosphingosine  0   Sphingosine/*analogs & derivatives. Curr Protoc Cell Biol 2001 May;Chapter 4; Unit 4.4
D-erythro-2-N-(160-(1''-pyridinium)hexadecanoyl)sphingosine bromide  0   *Ceramides Sphingosine/*analogs & derivatives. Br J Cancer 2008 Jan 15;98(1):98-105
FTY 720P  0   *Phosphoric Acid Esters Sphingosine/*analogs & derivatives. Glia 2007 Dec;55(16):1656-67
GlcCer-I6 sulfate  0   Sphingosine/*analogs & derivatives. J Oleo Sci 2007;56(3):129-36
((2S,3R)-2-amino-3-hydroxy-4-(4-octylphenyl)butyl phosphoric acid)  0   *Phosphoric Acids Sphingosine/*analogs & derivatives. J Pharm Pharmacol. 2007 Jul;59(7):1035-41
D-ribo-phytosphingosine  0   Sphingosine/*analogs & derivatives. J Org Chem 2006 Oct 27;71(22):8661-4
D-erythro-azidosphingosine  0   Sphingosine/*analogs & derivatives. J Org Chem 2006 Oct 27;71(22):8661-4
tetraacetyl-phytosphingosine  0   Sphingosine/*analogs & derivatives. Exp Dermatol 2007 Apr;16(4):311-7
D-arabino-phytosphingosine  0   Sphingosine/*analogs & derivatives. Chem Commun (Camb). 2006 Feb 14;(6):655-7
L-ribo-phytosphingosine  0   Sphingosine/*analogs & derivatives. Chem Commun (Camb). 2006 Feb 14;(6):655-7
1-deoxysphingosine  0   Sphingosine/*analogs & derivatives. Org Lett 2006 Feb 16;8(4):649-52
asteriaceramide A  0   *Ceramides Sphingosine/*analogs & derivatives. J Nat Prod 2006 Jul;69(7):1080-2
flavicerebroside B  0   *Cerebrosides Sphingosine/*analogs & derivatives. J Asian Nat Prod Res. 2004 Dec;6(4):249-57
flavicerebroside A  0   *Cerebrosides Sphingosine/*analogs & derivatives. J Asian Nat Prod Res. 2004 Dec;6(4):249-57
sulfamisterin  0   Sphingosine/*analogs & derivatives. Biochemistry 2005 Jan 11;44(1):268-77
(4,5-3H)-dihydrosphingosine-1-phosphate  0   *Phospholipids Sphingosine/*analogs & derivatives Tritium. Br J Pharmacol. 2004 Jul;142(5):851-60
(2S,3S,4R)-2-((2'R)-2'-hydroxynonadecanoylamino)nonadecane-1,3,4-triol  0   Sphingosine/*analogs & derivatives. J Nat Prod 2004 Aug;67(8):1423-5
(2S,3R)-2-(docosanoylamino)nonadecane-1,3-diol  0   Sphingosine/*analogs & derivatives. J Nat Prod 2004 Aug;67(8):1423-5
N-(N'-phenethylthiocarbamoyl)sphingosine  0   Sphingosine/*analogs & derivatives Thiourea/*analogs & derivatives. J Pharmacol Exp Ther 2004 May;309(2):452-61
N-(N'-phenethylthiocarbamoyl)sphinganine  0   Sphingosine/*analogs & derivatives Thiourea/*analogs & derivatives. J Pharmacol Exp Ther 2004 May;309(2):452-61
erythro-(2R,3S)-sphingosine  0   Sphingosine/*analogs & derivatives. J Org Chem. 2003 Sep 5;68(18):7094-7
lyxo-phytosphingosine  0   Sphingosine/*analogs & derivatives. J Org Chem 2003 Sep 5;68(18):7094-7
pachastrissamine  0   Sphingosine/*analogs & derivatives. J Nat Prod 2002 Oct;65(10):1505-6
erythro-dihydrosphingosine  0   Sphingosine/*analogs & derivatives. Org Lett 2002 May 16;4(10):1719-22
xylo-phytosphingosine  0   Sphingosine/*analogs & derivatives. Org Lett 2002 May 16;4(10):1719-22
S-15183b  0   Sphingosine/*analogs & derivatives Mitosporic Fungi. J Antibiot (Tokyo) 2001 May;54(5):415-20
S-15183a  0   Sphingosine/*analogs & derivatives Mitosporic Fungi. J Antibiot (Tokyo) 2001 May;54(5):415-20
3-O-benzoyl azidosphingosine  0   *Azides Sphingosine/*analogs & derivatives. Carbohydr Res 2001 Mar 9;331(1):91-4
2-amino-9-methyl-4,8,10-octadecatriene-1,3-diol  0   Sphingosine/*analogs & derivatives. J Lipid Res 2000 Jul;41(7):1118-24
2-aminotetradec-7-ene-1,3-diol  0   Sphingosine/*analogs & derivatives. J Nat Prod 2000 Jul;63(7):978-80
sialyl 2-1 sphingosine  0   *Glycosphingolipids Sphingosine. Biochemistry 2000 Mar 14;39(10):2459-68
lipid Z  0   Sphingosine. Proc Natl Acad Sci USA 1999 Jul 20;96(15):8402-7
sphingenine-1-phosphate  0   Sphingosine. FEBS Lett 1999 Jun 25;453(3):269-72
N-acetylsphingenine-1-phosphate  0   Sphingosine. FEBS Lett 1999 Jun 25;453(3):269-72
phytosphingosine-1-phosphate  0   Sphingosine/*analogs & derivatives. J Lipid Res 1999 Jan;40(1):117-25
caged sphingosine 1-phosphate  0   *Phosphoric Acid Esters Sphingosine/*analogs & derivatives. Bioorg Med Chem Lett 1998 Apr 7;8(7):711-4
N-methylsphingosine  0   Sphingosine/*analogs & derivatives. Nutr Cancer 1998;31(2):119-26
3-deoxysphingosine  0   Sphingosine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1997 Dec;45(12):2116-8
N-octanoylsphinganine  0   Sphingosine/*analogs & derivatives. J Biol Chem 1997 Sep 5;272(36):22432-7
N-thioacetylsphingosine  0   Sphingosine/*analogs & derivatives Apoptosis. FEBS Lett 1997 Jul 14;411(2-3):260-4
4-methylsphingosine 1-phosphate  0   Sphingosine/*analogs & derivatives. J Biol Chem 1997 Jun 20;272(25):15825-33
4-methylsphingosine  0   Sphingosine/*analogs & derivatives. J Biol Chem 1997 Jun 20;272(25):15825-33
N,N-dimethylsphingosine-1-phosphate  151729-53-2   Sphingosine/*analogs & derivatives. Biochem Biophys Res Commun 1997 Feb 24;231(3):848-51
fingolimod  162359-55-9 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol  *Propylene Glycols Sphingosine/*analogs & derivatives.
Pharma Action Immunosuppressive Agents 		Transplantation 1996 Jan 27;61(2):200GILENYA
1-O-glucopyranosyl-N-(32'-linoleoyloxy-23'-dotriacontenoyl)-4-sphingenine  0   Sphingosine/*analogs & derivatives. Biosci Biotechnol Biochem 1995 Sep;59(9):1641-3
3-O-methylsphinganine  0   Sphingosine/*analogs & derivatives. Biochem J 1995 Apr 1;307(Pt 1):107-13
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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