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Spider Venoms

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Definition: Venoms of arthropods of the order Araneida of the ARACHNIDA. The venoms usually contain several protein fractions, including ENZYMES, hemolytic, neurolytic, and other TOXINS, BIOLOGICAL.  /antag permitted but consider also ANTIVENINS; /enzymol permitted   
See Also Arachnidism
Examples Agatoxins 		Other names Venoms, Tarantula; Venoms, Spider; Venoms, Araneid; Venoms, Arachnid; Venom, Spider; Venom, Araneid; Venom, Arachnid; Tarantula Venoms; Spider Venom; Araneid Venom; Arachnid Venom; Araneid Venoms; Arachnid Venoms
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
parawixin 10, Parawixia bistriata  0   *Spider Venoms Anticonvulsants. Epilepsy Behav. 2011 Oct;22(2):158-64
stromatoxin protein, Stromatopelma calceata  0   *Peptides *Spider Venoms Shab Potassium Channels/antagonists & inhibitors. Chem Res Toxicol 2003 Oct;16(10):1217-25
omega-phonetoxin-IIA, Phoneutria nigriventer  0   *Peptides *Spider Venoms. Pflugers Arch 1998 Jul;436(4):545-52
argiotoxin-636  0   *Indoleacetic Acids *Polyamines Spider Venoms. J Nat Prod. 2011 Mar 25;74(3):483-6
JSTX-4 spider toxin  0   *Spider Venoms. J Nat Prod. 2011 Mar 25;74(3):483-6
nigriventrine  0   *Pipecolic Acids *Spider Venoms. Toxicon. 2011 Feb;57(2):266-74
LyeTx I protein, Lycosa erythrognatha  0   *Antimicrobial Cationic Peptides Spider Venoms. Amino Acids 2010 Jun;39(1):135-44
GxTX-1E, Plesiophrictus guangxiensis  0   *Peptides *Spider Venoms Neurotoxins. Biochemistry. 2010 Jun 29;49(25):5134-42
purotoxin-1, Geolycosa  0   *Spider Venoms. Ann Neurol. 2010 May;67(5):680-3
Jingzhaotoxin-IX  0   *Peptides Spider Venoms. Neuropharmacology. 2009 Aug;57(2):77-87
jingzhaotoxin-34, Chilobrachys jingzhao  0   *Spider Venoms. Peptides 2009 Jun;30(6):1042-8
NPTX-594  0   *Polyamines Spider Venoms. Protein Pept Lett 2009;16(3):285-8
Tx2-6 protein, Phoneutria nigriventer  0   *Peptides *Spider Venoms. FEBS Lett 2002 Jul 17;523(1-3):219-23
Tx2-5 protein, Phoneutria nigriventer  0   *Peptides *Spider Venoms. Biochemistry 2009 Apr 14;48(14):3078-88
jingzhaotoxin-IV, Chilobrachys jingzhao  0   *Peptides *Spider Venoms. Toxicon 2008 Dec 15;52(8):871-80
jingzhaotoxin-II, Chilobrachys jingzhao  0   *Spider Venoms. Biochem Pharmacol 2008 Dec 15;76(12):1716-27
LTx2 neurotoxin, Lasiodora  0   *Spider Venoms. Toxicon 2004 Dec 15;44(8):949-52
latarcin 2a, Lachesana tarabaevi  0   *Spider Venoms *Antimicrobial Cationic Peptides. Protein Expr Purif 2008 Jul;60(1):89-95
huwentoxin-V, Ornithoctonus huwena  0   *Spider Venoms. Eur J Pharmacol 2008 Mar 17;582(1-3):12-6
Ltc2a peptide, Lachesana tarabaevi  0   *Spider Venoms *Antimicrobial Cationic Peptides. Biochemistry 2006 Sep 5;45(35):10759-67
Ltc1 peptide, Lachesana tarabaevi  0   *Spider Venoms *Antimicrobial Cationic Peptides. Bioorg Khim 2007 Jul-Aug;33(4):405-12
jingzhaotoxin XI, Chilobrachys jingzhao  0   *Peptides *Spider Venoms. Biochemistry 2006 Dec 26;45(51):15591-600
HpTx-2 protein, Heteropoda venatoria  0   *Spider Venoms. Protein Sci 2000 Nov;9(11):2059-67
CSTX-1, Cupiennius salei  0   *Spider Venoms. Neuropharmacology 2007 Jun;52(8):1650-62
PRTx3-7 toxin  0   *Spider Venoms Neurotoxins. Cell Mol Neurobiol. 2007 Feb;27(1):129-46
jingzhaotoxin-V, Chilobrachys jingzhao  0   *Peptides *Spider Venoms. Toxicon 2007 Mar 1;49(3):388-99
dermonecrotic toxin, Loxosceles intermedia  0   *Spider Venoms. Biochimie 2006 Sep;88(9):1241-53
hwentoxin-X, Ornithoctonus huwena  0   *Spider Venoms. J Biol Chem 2006 Mar 31;281(13):8628-35
PwTX-II  0   *Carbolines *Spider Venoms Toxins, Biological. Toxicon. 2005 Dec 1;46(7):786-96
delta-palutoxin IT2, Paracoelotes lunctuosus  0   *Spider Venoms. Eur J Biochem 2000 Sep;267(18):5783-95
jingzhaotoxin-I, Chilobrachys jingzhao  0   *Peptides *Spider Venoms. J Biol Chem 2005 Apr 1;280(13):12069-76
Selenocosmia huwena toxin-I  0   *Spider Venoms. Acta Biochim Biophys Sin (Shanghai). 2004 Oct;36(10):656-60
sphingomyelinase I, Loxosceles laeta  EC 3.1.4.12   *Sphingomyelin Phosphodiesterase *Spider Venoms. Acta Crystallogr D Biol Crystallogr 2004 Jun;60(Pt 6):1112-4
phrixotoxin I, Phrixotrichus auratus  0   *Spider Venoms. Protein Sci 2004 May;13(5):1197-208
Magi toxin  0   *Spider Venoms. Toxicon. 2004 Aug;44(2):149-56
psalmopeotoxin II, Psalmopoeus cambridgei  0   *Spider Venoms. FEBS Lett 2004 Aug 13;572(1-3):109-117
psalmopeotoxin I, Psalmopoeus cambridgei  0   *Spider Venoms. FEBS Lett 2004 Aug 13;572(1-3):109-17
hainantoxin III, Seleconosmia hainana  0   *Spider Venoms. Eur J Pharmacol 2003 Sep 5;477(1):1-7
VSTX1 protein, Grammostola spatulata  0   *Peptides *Spider Venoms. Nature 2004 Jul 8;430(6996):232-5
jingzhaotoxin-III, Chilobrachys jingzhao  0   *Peptides *Spider Venoms. J Biol Chem 2004 Jun 18;279(25):26220-6
huwentoxin III  0   *Spider Venoms. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003 Nov;35(11):976-80
PnTx4-3  0   *Neuropeptides Spider Venoms. Toxicon. 2003 Dec;42(7):793-800
loxnecrogin protein, Loxosceles gaucho  0   *Spider Venoms *Insect Proteins Dermotoxins. J Protein Chem 2003 Feb;22(2);135-46
huwentoxin-V, Selenocosmia huwena  0   *Spider Venoms Neurotoxins. Toxicon 2003 Jul;42(1);15-20
hainantoxin-IV, Seleconosmia hainana  0   *Spider Venoms Cystine Knot Motifs. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 2003 Jan;35(1):82-5
huwentoxin IV, Selenocosmia huwena  0   *Spider Venoms. J Biol Chem 2002 Dec 6;277(49):47564-71
ProTx-II peptide  0   *Spider Venoms. Biochemistry 2002 Dec 17;41(50):14734-47
ProTx-I peptide  0   *Spider Venoms. Biochemistry 2002 Dec 17;41(50):14734-47
cupiennin 1D, Cupiennius salei  0   *Spider Venoms *Antimicrobial Cationic Peptides. FEBS Lett 2002 Sep 11;527(1-3):193-8
cupiennin 1a  0   *Peptides *Spider Venoms. J Biol Chem 2002 Mar 29;277(13):11208-16
atracotoxin-Hi-OB4219  0   *Spider Venoms. Biochemistry 2002 Mar 12;41(10):3294-301
omega-atracotoxin Hv2a  0   *Spider Venoms. J Biol Chem 2001 Oct 26;276(43):40306-12
CSTX-9, Cupiennius salei  0   *Spider Venoms. Cell Mol Life Sci 2001 Sep;58(10):1538-45
Tx4 neurotoxin  0   *Spider Venoms. Toxicon 2001 Feb-Mar;39(2-3):309-17
PcTX1 protein, Psalmopoeus cambridgei  0   *Spider Venoms Sodium Channels/antagonists & inhibitors. J Biol Chem 2000 Aug 18;275(33):2516-21
CSTX-2a protein, Cupiennius salei  0   *Spider Venoms Neurotoxins. Arch Insect Biochem Physiol 2000 Jul;44(3):101-11
MTx4 protein, Grammostola spatulata  0   *Peptides *Spider Venoms. J Gen Physiol 2000 May;115(5):583-98
covalitoxin II  0   *Spider Venoms. FEBS Lett 2000 Jun 2;474(2-3):208-12
HO 416b  0   *Indoles *Polyamines Spider Venoms. Org Lett 2000 Jan 1;2(11):1581-3
delta-atracotoxin-HV1  0   *Spider Venoms. FEBS Lett 2000 Mar 31;470(3):293-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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