encyclopedia of medical concepts
ψ 

Spin Labels

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Definition: Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)  /chem syn permitted   
See Also Electron Spin Resonance Spectroscopy; Spin Trapping
Examples Triacetoneamine-N-Oxyl
Other names Labels, Spin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,2,4,4-tetramethylpiperdine-1-oxyl  0   *Cyclic N-Oxides Spin Labels. Chemistry. 2010 Nov 8;16(42):12718-26
2,2',5,5'-tetra(tert-butyl)-4,4'-bis(ethoxycarbonyl)-3,3'-bipyrrolyl-1,1'-dioxyl  0   *Cyclic N-Oxides *Pyrroles Spin Labels. J Am Chem Soc 2009 Jul 29;131(29):10092-106
1-acetoxy-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine  0   *Acetates *Pyrrolidines Spin Labels. J Med Chem 2002 May 23;45(11):2283-8
N-2-(2-ethoxycarbonylpropyl)phenylnitrone  0   *Benzene Derivatives Spin Labels. Arch Biochem Biophys 2002 Jan 1;397(1):51-6
3-(2,2,5,5-tetramethylpyrrolidine-1-oxyl)-3-(fluorosulfonyl)benzamide  0   *Cyclic N-Oxides Spin Labels. J Protein Chem 2000 Feb;19(2):129-37
3-oxo-androstan-17-yl-(2'',2'',6'',6''-tetramethyl-N-oxyl)piperidyl butan-1',4'-dioate  0   *Androstanes Spin Labels. Indian J Biochem Biophys 2000 Feb;37(1):45-50
5-ethoxycarbonyl-5-methyl-1-pyrroline N-oxide  0   *Cyclic N-Oxides Spin Labels. FEBS Lett 2000 May 4;473(1):58-62
2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide  0   *Pyrroles Spin Labels. Free Radic Biol Med 2000 Feb 1;28(3):403-8
1-(2-hydroxy-3-octadecan-1'-oate)propyl-2'',2'',5'',5''-tetramethylpyrrolidine-N-oxyl-3''-carboxylate  0   *Cyclic N-Oxides *Pyrrolidines Spin Labels. Bioorg Med Chem 1999 Dec;7(12):2753-8
N,N',N''-tris-(1-oxyl-2,2,6,6-tetramethylpiperidine-4-yl)-1,3,5-tnazine-2,4,6-triamine  0   *Azo Compounds *Piperidines Spin Labels. Anticancer Res 1999 Jul-Aug;19(4B):3343-8
(N-dithiocarboxysarcosine)iron(III)  0   *Ferric Compounds *Thiocarbamates Spin Labels. Eur J Biochem 1999 Dec;266(3):771-7
DRD 157  0   *Pyrazoles Spin Labels. Free Radic Biol Med 1999 May;26(9-10):1339-45
DRD 156  0   *Pyrazoles Spin Labels. Free Radic Biol Med 1999 May;26(9-10):1339-45
azido-LPC  0   *Glycerol *Phosphorylcholine Spin Labels. Biochim Biophys Acta 1999 Jul 9;1439(1):47-56
2,2,6,6-tetramethyl-4-acetamido-piperidine-1-oxyl  0   *Cyclic N-Oxides Spin Labels. Arch Oral Biol 1999 Mar;44(3):259-67
diethyl(2-methyl-2-pyrrolidinyl)phosphonate  0   *Phosphonic Acids *Pyrrolidines Spin Labels. Eur J Biochem 1998 Jun 1;254(2):256-65
DanePy  0   *Dansyl Compounds *Piperidines Spin Labels. Free Radic Biol Med 1998 Mar 1;24(4):649-52
MCPROXYL  0   *Cyclic N-Oxides *Pyrrolidines Spin Labels. FEBS Lett 1997 Dec 8;419(1):99-102
2,2-dimethyl-4-methyl-2H-imidazole-1-oxide-N  0   *Imidazoles Spin Labels. Free Radic Res 1997 Feb;26(2):159-68
1-fluoro-5-(1-oxyl-2,2,6,6-tetramethylpiperidinylamino)-2,4-dinitrobenzene  0   *Nitrobenzenes Spin Labels. Chem Phys Lipids 1997 Jul 14;87(2):125-35
5'-(2-(N-tert-butylethanalnitrone))-1,3,3-trimethyl-spiro(indoline-2,3'-naphtho(2,1-b)(1,4)oxazine)  0   *Naphthalenes *Oxazines Spin Labels. Free Radic Res 1997 Jun;26(6):529-36
MDL 102832  0   *Isoquinolines Spin Labels. J Neurochem 1997 Mar;68(3):1173-82
5-methyl-5-phenylpyrroline-1-oxide  0   *Pyrroles Spin Labels. Free Radic Biol Med 1996;21(6):889-94
1-hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine  3637-11-4   *Piperidines Spin Labels. Biochem Biophys Res Commun 1997 Jan 3;230(1):54-7
glutathionyl-5,5-dimethyl-1-pyrroline N-oxide  0   *Cyclic N-Oxides Glutathione/*analogs & derivatives Spin Labels. Arch Biochem Biophys 1996 Jun 1;330(1):3-11
5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide  157230-67-6   *Cyclic N-Oxides Spin Labels. J Biol Chem 1996 Mar 15;271(11):6000-9
5-(3-((2,5-dihydro-2,2,5,5-tetramethyl-1-oxyl-1H-pyrrole-3-carboxamido)pentanamido)prop-1-enyl)-2'-deoxycytidine 5'-triphosphate  0   *Cyclic N-Oxides *Deoxycytosine Nucleotides Spin Labels. Arch Biochem Biophys 1995 Dec 20;324(2):357-66
4'-maleimido-4-((1-oxyl-2,2,5,5-tetramethyl-3-maleimidyl)carbonylamino)dihydrostilbene-2,2'-disulfonate  0   4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid/*analogs & derivatives Spin Labels. Biophys J 1995 Oct;69(4):1409-23
adenosine 5'-O-(S-acetamidoproxyl 3-thiotriphosphate)  0   *Cyclic N-Oxides Adenosine Triphosphate/*analogs & derivatives Spin Labels Thionucleotides. Biochemistry 1995 Nov 21;34(46):15068-74
(5,6)PA  0   Tetradecanoylphorbol Acetate/*analogs & derivatives Spin Labels. Carcinogenesis 1995 Oct;16(10):2589-92
4,4'-di-(tert-butyl)diphenyl-1-nitroxy  0   *Biphenyl Compounds Free Radicals Spin Labels. Biochem Biophys Res Commun 1995 Oct 4;215(1):192-8
proxyliodoacetamide  0   Iodoacetamide/*analogs & derivatives Spin Labels. Biochemistry 1995 Sep 26;34(38):12388-97
5,5-dimethyl-2-phenyl-1-pyrroline-N-oxide  58134-17-1   *Cyclic N-Oxides Spin Labels. Free Radic Res 1995 Jul;23(1):81-7
5,5-dimethyl-4-hydroxymethyl-1-pyrroline-N-oxide  0   *Cyclic N-Oxides Spin Labels. Free Radic Res 1995 Jul;23(1):15-25
5,5-dimethyl-4-phenyl-1-pyrroline-N-oxide  0   *Cyclic N-Oxides Spin Labels. Free Radic Res 1995 Jul;23(1):15-25
4,5,5-trimethyl-1-pyrroline-N-oxide  0   *Cyclic N-Oxides Spin Labels. Free Radic Res 1995 Jul;23(1):15-25
alpha-(4-(5-((2-carboxy)phenyl)-5-hydroxy-4-oxo-3-phenyl-2-pyrrolin-1-yl)phenyl)-N-(tert-butyl)nitrone  0   *Pyrroles Spin Labels. FASEB J 1995 Aug;9(11):1085-90
succinimidyl-2,2,5,5-tetramethyl-3-pyrroline-1-oxyl-3-carboxylate  58537-73-8   *Cyclic N-Oxides Spin Labels. Arch Biochem Biophys 1995 Jun 20;320(1):155-61
3,4-dihydro-3,3-dimethylisoquinoline-N-oxide  0   *Isoquinolines Spin Labels. Ann N Y Acad Sci 1994 Nov 17;738:243-9
3-(2-iodopropionyl)-1-oxyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrole  0   *Cyclic N-Oxides Spin Labels. Biochemistry 1994 Nov 29;33(47):14317-323
2'-(3-benzyloxy-24-norcholan-23-yl)-2'-4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl  157751-99-0   *Cyclic N-Oxides *Oxazoles Spin Labels. Steroids 1994 Jun;59(6):377-82
3-(methoxycarbonyl)-4-(4'-(chloromercuri)benzamido)methyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl  0   *Cyclic N-Oxides *Organomercury Compounds Spin Labels. Biochemistry 1994 Mar 29;33(12):3693-7
2,2,6,6-tetramethyl-4-capryloylpiperidine-1-oxyl  126328-27-6   *Caprylates *Cyclic N-Oxides Spin Labels. Int J Biochem 1993 Jul;25(7):971-7
2-((1-oxyl-2,2,5,5-tetramethyl-3-pyrrolin-3-yl)methenyl)indane-1,3-dione  124558-37-8   *Cyclic N-Oxides *Indans Spin Labels. Biophys J 1993 Jun;64(6):1896-1907
lithium phthalocyanine  111716-29-1   *Indoles *Organometallic Compounds Lithium Spin Labels. Proc Natl Acad Sci USA 1993 Jun 15;90(12):5438-42
3-(2,2,5,5-tetramethyl-1--oxypyrrolidinyl)-2-propen-1-ol  76893-25-9   *Cyclic N-Oxides *Pyrrolidines Spin Labels. Adv Exp Med Biol 1993;328:501-12
3-(2,2,5,5-tetramethyl-1-oxypyrrolidinyl)-2-propenal  76893-26-0   *Cyclic N-Oxides *Pyrrolidines Spin Labels. Adv Exp Med Biol 1993;328:501-12
4-hydroxy-2,2,6,6-tetramethyl-4-(3-picrylaminomethyl)piperidine N-oxide  148719-46-4   *Cyclic N-Oxides *Picrates Spin Labels. Biophys J 1993 Mar;64(3):642-53
2,2,6,6-tetramethyl-4-(3-picrylamino)piperidine N-oxide  115044-44-5   *Cyclic N-Oxides *Picrates Spin Labels. Biophys J 1993 Mar;64(3):642-53
5-aminoeosin  75900-75-3   Eosine Yellowish-(YS)/*analogs & derivatives Spin Labels. Biophys J 1993 Mar;64(3):605-13
1,2,2,4,5,5,-hexamethyl-3-imidazolidine oxide  64934-84-5   *Cyclic N-Oxides *Imidazolidines Spin Labels. Basic Res Cardiol 1992 Nov-Dec;87(6):536-47
2,5,5-trimethyl-1-pyrroline N-oxide  4567-18-4   *Cyclic N-Oxides Spin Labels. Biochem Int 1992 Aug;27(4):651-9
4-(N-carboxydecyl-N-methylamino)-TEMPO  139116-77-1   *Cyclic N-Oxides *Methylamines Spin Labels. Biomaterials 1991 Oct;12(8):715-21
4-(N-carboxybutyl-N-methylamino)-TEMPO  139116-76-0   *Cyclic N-Oxides *Methylamines Spin Labels. Biomaterials 1991 Oct;12(8):715-21
4-(N-carboxymethyl-N-methylamino)-TEMPO  139116-75-9   *Cyclic N-Oxides *Methylamines Spin Labels. Biomaterials 1991 Oct;12(8):715-21
N-tert-butylhydroxylamine  16649-50-6   *Hydroxylamines Spin Labels. Free Radic Res Commun 1991;14(5-6):395-407
5,6-benzo-2,2,4,4-tetramethyl-1,2,3,4-tetrahydro-gamma-carboline-oxyl  32890-80-5   *Carbolines *Cyclic N-Oxides Spin Labels. J Cell Biochem 1991 Jul;46(3):260-5
2,2,6,6-tetramethyl-4-capryloyl-oxypiperidine-1-oxyl  22491-88-9   *Caprylates *Cyclic N-Oxides Spin Labels. J Cell Biochem 1991 Jul;46(3):260-5
5-amino-(2,2,6,6-tetramethylpiperidine-N-oxyl)uridine 5'-triphosphate  136134-11-7   *Cyclic N-Oxides Uridine Triphosphate/*analogs & derivatives Spin Labels. J Biol Chem 1991;266(27):17936
N-2,4-dinitrophenyl (bis)glycine  56224-80-7   *Dinitrophenols Glycylglycine/*analogs & derivatives Spin Labels. J Mol Biol 1991;221(1):257
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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