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Spirostans

More information in Books or onNLM PubMed
Definition: Cholestane derivatives containing a fused lactone ring at the 16,17-position and a spiroglycosidic linkage at C-22. Members include sarsaponin, DIOSGENIN and yamogenin.     
Examples Diosgenin 		Other names Spirostenes; Spirostatrienes; Spirostanols; Spirostadienes
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(3beta,5alpha,6beta,25R)-6-((beta-D-glucopyranosyl)oxy)spirostan-3-yl O-beta-D-glucopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))beta-D-galactopyranoside  0   *Saponins *Spirostans. Fitoterapia. 2011 Dec;82(8):1175-80
21-nor-18,27-dimethyl-1,2,3-trihydroxy-25-spirost-4-en-19-oic acid  0   *Spirostans Sapogenins. Steroids 2011 Mar;76(4):358-64
25-spirostan-3,5,6,19-tetrol  0   *Spirostans. Steroids 2010 Mar;75(3):224-9
5alpha-spirostane-3beta,23,24-triol-3-O-(alpha-L-rhamnopyranosyl-(1 -2))-(beta-D-glucopyranosyl-(1-4)-beta-D-galactopyranoside)  0   *Saponins *Spirostans. J Asian Nat Prod Res. 2010 Jan;12(1):30-5
ophiopogonin G  0   *Saponins *Spirostans. J Asian Nat Prod Res. 2009 Sep;11(9):824-31
ophiopogonin F  0   *Saponins *Spirostans. J Asian Nat Prod Res. 2009 Sep;11(9):824-31
(23S,25R)-6alpha-((beta-D-glucopyranosyl)oxy)-23-hydroxy-5alpha-spirostan-3beta -yl beta -D-fucopyranoside  0   *Glycosides *Spirostans. Chem Pharm Bull (Tokyo). 2009 Oct;57(10):1161-6
chantrieroside A  0   *Glucosides *Spirostans. Chem Pharm Bull (Tokyo). 2009 Oct;57(10):1126-8
indioside F  0   *Glycosides *Spirostans. Chem Pharm Bull (Tokyo). 2009 Jul;57(7):747-8
borivilianoside F  0   *Saponins *Spirostans. J Nat Prod 2009 Jan;72(1):177-81
borivilianoside G  0   *Saponins *Spirostans. J Nat Prod 2009 Jan;72(1):177-81
borivilianoside H  0   *Saponins *Spirostans. J Nat Prod 2009 Jan;72(1):177-81
convallasaponin A  0   *Glycosides *Spirostans. Chem Pharm Bull (Tokyo) 2007 Feb;55(2):337-9
(22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate  0   *Caproates *Spirostans. Steroids. 2006 Aug;71(8):725-35
3-(O-beta-D-glucopyranosyl-(1-2)-O-(O-beta-D-glucopyranosyl-(1-4)-O-(O-beta-D-glucopyranosyl-(1-6))-O-beta-D-glucopyranosyl-(1-4)-beta-D-galactopyranosyl)-oxy)-(3beta,5alpha,25R)-spirostane  0   *Saponins *Spirostans. Nat Prod Res. 2006 Apr;20(4):385-90
spirost-5-ene-1,3,14,15-tetrol  0   *Spirostans. Steroids 2006 Feb;71(2):160-4
torvoside L  0   *Spirostans. Chem Pharm Bull (Tokyo). 2005 Sep;53(9):1122-5
torvoside J  0   *Spirostans. Chem Pharm Bull (Tokyo). 2005 Sep;53(9):1122-5
torvoside K  0   *Spirostans. Chem Pharm Bull (Tokyo). 2005 Sep;53(9):1122-5
(23S,25R)-12alpha,17alpha,23-trihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-glucopyranoside  0   *Saponins *Spirostans. J Nat Prod 2005 Jul;68(7):1116-20
(23S,25R)-14alpha,17alpha,23-trihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(12)-beta-D-glucopyranoside  0   *Saponins *Spirostans. J Nat Prod 2005 Jul;68(7):1116-20
(23S,24R,25S)-23,24-dihydroxyspirost-5-en-3beta-yl O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-glucopyranoside  0   *Saponins *Spirostans. J Nat Prod 2005 Jul;68(7):1116-20
aspaoligonin B  0   *Spirostans. J Nat Prod 2005 May;68(5):766-8
aspaoligonin A  0   *Saponins *Spirostans. J Nat Prod 2005 May;68(5):766-8
sansevistatin 2  0   *Saponins *Spirostans. J Nat Prod 2005 May;68(5):729-33
sansevistatin 1  0   *Saponins *Spirostans. J Nat Prod 2005 May;68(5):729-33
sansevierin A  0   *Saponins *Spirostans. J Nat Prod 2005 May;68(5):729-33
aspafilioside D  0   *Spirostans. J Asian Nat Prod Res. 2005 Feb;7(1):43-7
6alpha-O-(beta-D-xylopyranosyl-(1-3)-beta-D-quinovopyranosyl)-(25S)-5alpha-spirostan-3beta-ol  0   *Saponins *Spirostans. J Nat Prod 2004 Jun;67(6):938-41
6alpha-O-beta-D-quinovopyranosyl-(25S)-5alpha-spirostan-3beta-ol  0   *Saponins *Spirostans. J Nat Prod 2004 Jun;67(6):938-41
asparacosin B  0   *Spirostans. J Nat Prod 2004 Feb;67(2):194-200
asparacosin A  0   *Spirostans. J Nat Prod 2004 Feb;67(2):194-200
asparacoside  0   *Saponins *Spirostans. J Nat Prod 2004 Feb;67(2):194-200
2,3,23-trihydroxy-5-spirostan-6-one  0   *Spirostans. Steroids 2002 Mar;67(3-4):159-63
2,3-dihydroxy-5-spirostan-6,23-dione  0   *Spirostans. Steroids 2002 Mar;67(3-4):159-63
tigogenin hexasaccharide-1  0   *Saponins *Spirostans. Can J Physiol Pharmacol 2001 Nov;79(11):953-8
tigogenin hexasaccharide-2  0   *Saponins *Spirostans. Can J Physiol Pharmacol 2001 Nov;79(11):953-8
namogenin B  0   *Sapogenins *Spirostans. J Nat Prod 2001 Sep;64(9):1127-32
namogenin C  0   *Sapogenins *Spirostans. J Nat Prod 2001 Sep;64(9):1127-32
namogenin A  0   *Sapogenins *Spirostans. J Nat Prod 2001 Sep;64(9):1127-32
3-O-(quinovopyranosyl(1-6)glucopyranosyl(1-6)glucopyranosyl)chlorogenin  0   *Saponins *Spirostans. Planta Med 2001 Jun;67(4):372-4
5alpha-spirostane-12-one-3beta-ol-3-O-beta-xylopyranosyl(1-2)- (beta-xylopyranosyl(1-3))-beta-glucopyranosyl(1-4)-(alpha-rhamno- pyranosyl(1-2))-beta-galactopyranoside  0   *Saponins *Spirostans. Planta Med 2001 Mar;67(2):196-8
ruscogenin-1-yl xylopyranosyl-1-3-(glucopyranosyl-1-2)fucopyranoside  0   *Saponins *Spirostans. Carbohydr Res 2000 Dec 1;329(4):745-54
tupichigenin C  0   *Sapogenins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Sep;48(9):1350-3
tupichigenin B  0   *Sapogenins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Sep;48(9):1350-3
nigrumnin II  0   *Saponins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Jul;48(7):1062-4
nigrumnin I  0   *Saponins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Jul;48(7):1062-4
chloromaloside A  133024-11-0   *Saponins *Spirostans. Planta Med 2000 Aug;66(6):587-90
dihydroxy-spirostan-12-one 3,6-di-O-glucopyranoside  0   *Saponins *Spirostans. Planta Med 2000 May;66(4):393-6
laxogenin  1177-71-5   *Spirostans. Biol Pharm Bull 2000 May;23(5):660-2
anguivioside C  0   *Saponins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Apr;48(4):568-70
anguivioside B  0   *Saponins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Apr;48(4):568-70
anguivioside A  0   *Saponins *Spirostans. Chem Pharm Bull (Tokyo) 2000 Apr;48(4):568-70
furcreastatin  0   *Saponins *Spirostans. Carbohydr Res 2000 Jan 12;323(1-4):57-62
L 166143  0   *Saponins *Spirostans. J Lipid Res 1999 Oct;40(10):1747-57
tuberoside E  0   *Glycosides *Spirostans. J Nat Prod 1999 Jul;62(7):1028-9
tuberoside D  0   *Glycosides *Spirostans. J Nat Prod 1999 Jul;62(7):1028-9
5-spirostan-3-ol 3-O-(glucopyranosyl-1-2-(arabinopyranosyl-1-6)glucopyranoside)  0   *Saponins *Spirostans. Phytochemistry 1999 Aug;51(8):1069-75
3-hydroxy-5-spirostan-12-one 3-O-(glucopyranosyl-1-2-(arabinopyranosyl-1-6)glucopyranoside)  0   *Saponins *Spirostans. Phytochemistry 1999 Aug;51(8):1069-75
spirost-5-ene-3,23-diol-23-O-(O-glucopyranosyl-(1-6)-glucopyranoside)  0   *Spirostans *Saponins. Phytochemistry 1999 Jul;51(5):689-92
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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