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Carbon-Sulfur Lyases

More information in Books or onNLM PubMed
Definition: Enzymes that catalyze the cleavage of a carbon-sulfur bond by means other than hydrolysis or oxidation. EC 4.4.  DF: C S LYASES   
Examples Cystathionine gamma-Lyase; Lactoylglutathione Lyase
Other names Sulfhydrases; Lyases, Carbon-Sulfur; Carbon Sulfur Lyases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
farnesylcysteine lyase, Arabidopsis  EC 4.4.-   *Carbon-Sulfur Lyases *Arabidopsis Proteins. Plant J 2007 Jun;50(5):839-47
Nfs1 protein, mouse  EC 4.4.1.-   *Carbon-Sulfur Lyases. FEBS Lett 1998 Aug 14;433(1-2):143-8
NFS1 protein, human  EC 4.4.1.-   *Carbon-Sulfur Lyases. Mol Cell 1998 Dec;2(6):807-15
SeMet alpha,gamma-elimination enzyme, mouse  EC 4.4.-   *Carbon-Sulfur Lyases. Biol Trace Elem Res 2005 Jul;106(1):77-94
rituximab-alliinase conjugate  0   *Carbon-Sulfur Lyases *Antibodies, Monoclonal, Murine-Derived. Mol Cancer Ther 2005 Feb;4(2):325-31
methoxypolyethylene glycol succinimidyl glutarate methioninase conjugate  EC 4.4.1.11   *Polyethylene Glycols *Carbon-Sulfur Lyases. Cancer Res 2004 Sep 15;64(18):6673-8
Pcyox1 protein, mouse  EC 1.8.3.5   *Carbon-Sulfur Lyases.
PCYOX1 protein, human  EC 1.8.3.5   *Carbon-Sulfur Lyases.
PEG-methioninase  EC 4.4.1.-   *Polyethylene Glycols *Carbon-Sulfur Lyases Drug Carriers. Adv Exp Med Biol. 2003;519:69-79
(2R)-phospho-3-sulfolactate synthase  EC 4.4.-   *Carbon-Sulfur Lyases. J Biol Chem 2002 Apr 19;277(16):13421-9
2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (epoxyalkane-ring forming)  EC 4.2.99.19   *Carbon-Sulfur Lyases. Biochemistry 2002 Apr 16;41(15):5005-14
dimethylsulfoniopropionate lyase  EC 4.4.-   *Carbon-Sulfur Lyases. Appl Environ Microbiol 1999 Nov;65(11):5075-81
LuxS protein, Bacteria  EC 4.4.1.21   *Bacterial Proteins *Carbon-Sulfur Lyases Luminescent Agents. Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1639-44
cysteine-S-conjugate beta-lyase  EC 4.4.1.13   *Carbon-Sulfur Lyases. Biosci Biotechnol Biochem 1997 Aug;61(8):1327-30
cysteine sulfinate desulfinase  EC 4.4.1.-   *Carbon-Sulfur Lyases. J Biol Chem 1997 Sep 5;272(36):22417-24
prenylcysteine lyase  EC 1.8.3.5   *Carbon-Sulfur Lyases. J Biol Chem 1997 Sep 12;272(37):23354-9
L-cysteine-cystine C-S lyase  EC 4.4.1.-   *Carbon-Sulfur Lyases. J Biol Chem 1997 Apr 18;272(16):10442-7
cysteine desulfurase  EC 4.4.1.-   *Carbon-Sulfur Lyases Escherichia coli Proteins. J Biol Chem 1998 May 22;273(21):13264-72; Proc Natl Acad Sci U S A 1993 Apr 1;90(7):2754-8
L-methionine gamma-lyase  EC 4.4.1.11   *Carbon-Sulfur Lyases.
Pharma Action Antimetabolites, Antineoplastic
Biochemistry 16(1):100;1977; Biochemistry 18(21):4690;1979; Biochemistry 18(3):407;1979; Cancer Res 33(8):1862;1973; Cancer Res 33(8):1866;1973; Cancer Treat Rep 63(6):1069;1979; FEBS Lett 84(2):309;1977; J Biochem (Tokyo) 78:1105;1975; J Biochem (Tokyo) 80(6):1327;1976
cysteine lyase  EC 4.4.1.10   *Carbon-Sulfur Lyases. Biokhimiia 40(2):248;1975; Eur J Biochem 53:429;1975
S-alkylcysteine lyase  EC 4.4.1.6   *Carbon-Sulfur Lyases. J Biol Chem 253(24):8854;1978
alliin lyase  EC 4.4.1.4   *Carbon-Sulfur Lyases. Arch Biochem Biophys 193(1):150;1979; Biokhimiia 43(10):1905;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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