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Sulfides

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Definition: Chemical groups containing the covalent sulfur bonds -S-. The sulfur atom can be bound to inorganic or organic moieties.     
Examples Disulfides 		Other names Thioethers; Ethers, Sulfur; Sulfur Ethers
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Cu2ZnSnS4  0   *Tin *Copper *Sulfides *Zinc Nanoparticles. Chemistry. 2012 Mar 12;18(11):3127-31
(methylthio)methanethiol  0   *Sulfhydryl Compounds *Sulfides. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3492-7.
methyl 2-(methylthio)benzoate  0   *Benzoates *Sulfides Sex Attractants. Naturwissenschaften. 2003 Nov;90(11):517-20.
4,4'-bis(3-(4-trifluoromethylphenyl)thiourea)diphenyl sulfide  0   *Sulfides Thiourea/*analogs & derivatives. Analyst. 2011 Dec 21;136(24):5151-6.
poly(ethylene glycol)-block-poly(propylene sulfide)-block-poly(ethylene imine)  0   *Polyethylene Glycols *Sulfides Polyethyleneimine/*analogs & derivatives Drug Carriers Gene Transfer Techniques. Biomaterials. 2011 Dec;32(36):9839.
heptakis(6-(2-aminoethylthio)-6-deoxy-2-O-octyloxycarbonylethylsulfanylpropyl)-beta-cyclodextrin  0   *Sulfides *beta-Cyclodextrins Drug Carriers. Org Biomol Chem. 2009 Sep 21;7(18):3763-71.
CPI 613  0   *Octanoic Acids *Sulfides. Drug Metab Lett. 2011 Aug;5(3):163-82.
6-(4-chlorophenylsulfanyl)-2,4-hexadienoic acid hydroxyamide  0   *Hydroxamic Acids *Sulfides Histone Deacetylase Inhibitors. Apoptosis. 2011 Sep;16(9):914-23.
dipropyl tetrasulfide  0   *Sulfides. Int J Oncol 2011 Apr;38(4):1103-11
coppersensor-3  0   *Boron Compounds *Sulfides. Proc Natl Acad Sci U S A 2011 Apr 12;108(15):5980-5
Lu AA21004  0   *Piperazines *Sulfides Receptor, Serotonin, 5-HT1A Receptors, Serotonin, 5-HT3. IDrugs 2010 Dec;13(12):900-10
methionol  0   *Sulfides *Propanols. J Agric Food Chem 2003 Jan 29;51(3):727-32
2-benzyl-5-(4-chlorophenyl)-6-(4-(methylthio)phenyl)-2H-pyridazin-3-one  0   *Pyridazines *Sulfides Interleukin-1beta/antagonists & inhibitors. Eur J Pharm Biopharm 2010 Oct;76(2):215-21
6-amino-2-(2-(4-tert-butylphenoxy)ethylsulfanyl)-1H-pyrimidin-4-one  0   *Pyrimidinones *Sulfides. Cancer Lett 2010 Dec 8;298(2):250-7
3-(4-tert-butyl-phenylsulfanyl)acrylic acid ethyl ester  0   *Acrylates *Sulfides. Bioorg Med Chem 2010 Jun 15;18(12):4178-86
2-(2'-((dimethylamino)methyl)-4'-iodophenylthio)benzenamine  0   *Aniline Compounds *Sulfides. Nucl Med Biol 2010 Jul;37(5):577-86
18-fluoro-4-thiaoleic acid  0   *Oleic Acids *Sulfides Fluorine Radioisotopes. J Nucl Med 2010 Aug;51(8):1310-7
2,6-dichloro-N-(2-(3-methylbenzylsulfanyl)ethyl)benzamide  0   *Benzamides *Sulfides. J Med Chem 2010 Jul 22;53(14):5302-19
gadolinium monosulfide  0   *Gadolinium *Sulfides. Chem Commun (Camb) 2010 May 14;46(18):3143-5
lithium sulfide  0   *Sulfides *Lithium Compounds. Nano Lett 2010 Apr 14;10(4):1486-91
bornite  0   *Copper *Ferrous Compounds *Sulfides. Arch Microbiol. 2010 Jul;192(7):531-40
4-(3-(4-(1-methyl-1H-pyrazol-5-yl)phenylthio)phenyl)-tetrahydro-2H-pyran-4-carboxamide  0   *Pyrazoles *Sulfides. J Pharmacol Exp Ther 2010 Jul;334(1):294-301
4-(phenylthio)butanoic acid  0   *Butyric Acids *Sulfides. J Am Soc Nephrol 2010 May;21(5):794-802
dimethyl 2,2'-sulfanediylbis(3-hydroxy-6-((2-hydroxy-6-methoxy-4-methylphenyl)carbonyl)-5-methoxybenzoate)  0   *Benzophenones *Sulfides. Chem Biodivers 2010 Jan;7(1):216-20
dicyanosulfide  0   *Nitriles *Sulfides. Chem Res Toxicol 2009 Sep;22(9):1622-8
2-trifluoromethyl-3-phenylthio-1,3-butadiene  0   *Butadienes *Sulfides. Org Lett 2009 Oct 15;11(20):4728-31
2-fluoro-3-phenylthio-1,3-butadiene  0   *Butadienes *Sulfides. Org Lett 2009 Oct 15;11(20):4728-31
methyl 4-tolylsulfide  0   *Sulfides. Drug Metab Pharmacokinet 2009;24(3):218-25
bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl)sulfide  0   *Phenols *Sulfides. Bioorg Khim. 2009 May-Jun;35(3):417-23
2,2'-(2,3-bis-phenylsulfanylnaphthalene-1,4-yloxy)diacetic acid  0   *Acetic Acids *Sulfides Ligands. Dalton Trans 2009 Apr 7;(13):2352-8
11-(1-piperazinyl)dibenzo(b,f)(1,4)thiazepine  0   *Piperazines *Sulfides. Pharm Dev Technol 2009;14(1):27-37
N,N'-bis((2-phenylthio)phenyl)-1,4-piperazinedicarboxamide  0   *Piperazines *Sulfides. Pharm Dev Technol 2009;14(1):27-37
N-(2-(phenylthio)phenyl)-1-piperazinecarboxamide  0   *Piperazines *Sulfides. Pharm Dev Technol 2009;14(1):27-37
N,N'-bis(2-(phenylthio)phenyl)urea  0   *Phenylurea Compounds *Sulfides. Pharm Dev Technol 2009;14(1):27-37
phenyl N-(2-(phenylthio)phenyl)carbamate  0   *Carbamates *Sulfides. Pharm Dev Technol 2009;14(1):27-37
2-(phenylthio)aniline  0   *Aniline Compounds *Sulfides. Pharm Dev Technol 2009;14(1):27-37
4-((4-bromophenyl)thio)-3-(diacetylamino)benzoic acid  0   *Aminobenzoic Acids *Sulfides. Mol Microbiol 2009 Jan;71(2):404-20
tetraarsenic tetrasulfide  0   *Arsenicals *Sulfides. Zhonghua Xue Ye Xue Za Zhi 2006 Apr;27(4):259-63
routhierite  0   *Sulfides. Acta Crystallogr C 2008 Dec;64(Pt 12):i95-6
gemmacin B  0   *Sulfides *Bicyclo Compounds, Heterocyclic. Org Biomol Chem 2008 Aug 21;6(16):2978-81
dimethyl tetrasulfide  0   *Sulfides. Biosci Biotechnol Biochem 2008 Aug;72(8):2176-83
4-(4-fluoro-2,1,3-benzoxadiazol-7-ylthio)-7-mercapto-2,1,3-benzoxadiazole  0   *Oxadiazoles *Sulfides. Talanta 2008 Jun 30;76(1):9-14
F45T-03  0   *Hydrocarbons, Fluorinated *Sulfides. Bioorg Med Chem Lett 2008 Aug 1;18(15):4291-3
F15T-03  0   *Hydrocarbons, Fluorinated *Sulfides. Bioorg Med Chem Lett 2008 Aug 1;18(15):4291-3
XM 462  0   *Ceramides *Sulfides. ChemMedChem 2008 Jun;3(6):946-53
3-((4-(4-(acridin-9-ylamino)phenylthio)phenyl)(3-hydroxypropyl)amino)propan-1-ol  0   *Acridines *Sulfides. Anticancer Drugs 2008 Apr;19(4):381-9
2-((4-(4-(acridin-9-ylamino)phenylthio)phenyl)(2-hydroxyethyl)amino)ethan-1-ol  0   *Acridines *Sulfides. Anticancer Drugs 2008 Apr;19(4):381-9
bis(2-phenylthioethyl)methylamine  0   *Diethylamines *Sulfides. Anal Chim Acta 2008 May 26;616(1):78-84
4-nitrophenyl methyl sulfide  0   *Sulfides. Org Biomol Chem 2008 Feb 21;6(4):762-71
fluorapacin  0   *Fluorobenzenes *Sulfides. J Pharm Biomed Anal 2008 Jan 7;46(1):206-10
AgBiS2  0   *Sulfides *Silver Compounds. Chem Commun (Camb) 2007 Dec 14;(46):4931-3
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-iodobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-bromobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-fluorobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
1,2,2-trithioeethyl ethylguaiacol  0   *Sulfides Guaiacol/*analogs & derivatives. Plant J 2008 Jan;53(2):368-79
4-(6-acetyl-3-(3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy)-2-propylphenoxy)butyric acid  0   *Butyric Acids *Sulfides. Drugs R D 2007;8(6):400-2
2-(4-(4-fluorobutyl)benzylsulfanyl)-3-methylchromen-4-one  0   *Chromones *Sulfides Electron Transport Complex I/antagonists & inhibitors. J Med Chem 2007 Sep 6;50(18):4304-15
bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide  0   *Sulfides *Thiadiazoles Glutaminase/antagonists & inhibitors. Biochem J 2007 Sep 15;406(3):407-14
rabeprazole-thioether  0   *Sulfides *2-Pyridinylmethylsulfinylbenzimidazoles. Eur J Clin Pharmacol. 2006 Feb;62(2):113-7
(2-(3-pyrazolyl)phenyl)diphenylphosphine sulfide  0   *Phosphines *Pyrazoles *Sulfides. Dalton Trans 2007 Jul 14;(26):2823-32
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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