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Sulfonylurea Compounds

More information in Books or onNLM PubMed
Definition:   hypoglycemics; DF: SULFONYLUREA CPDS   
Examples Acetohexamide; Carbutamide; Chlorpropamide; Gliclazide; Glipizide; Glyburide; Tolazamide; Tolbutamide 		Other names Compounds, Sulfonylurea
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MF 592  0   *Indoles *Sulfonylurea Compounds Receptors, Prostaglandin E, EP4 Subtype/antagonists & inhibitors. Bioorg Med Chem Lett 2011 Feb 1;21(3):1041-6
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea  0   *Sulfonylurea Compounds. Clin Toxicol (Phila). 2009 Sep;47(8):792-7
1-phenyl-3-(coumarin-6-yl)sulfonylurea  0   *Coumarins *Sulfonylurea Compounds. J Photochem Photobiol B 2008 Aug 21;92(2):98-102
halosulfuron methyl  0   *Sulfonylurea Compounds. J Agric Food Chem 2008 Aug 27;56(16):7367-72
N-tert-butyl-N'-(2-(3-'-methylphenylamino)-5-nitrobenzenesulfonyl)urea  0   *Sulfonylurea Compounds Diphenylamine/*analogs & derivatives. Prostaglandins Other Lipid Mediat 2007 Aug;84(1-2):14-23
mesosulfuron-methyl  0   *Sulfonylurea Compounds. Pest Manag Sci 2007 Apr;63(4):349-57
amidosulfuron  0   *Pyrimidines *Sulfonylurea Compounds. Toxicol Lett 2006 Feb 8;161(1):43-52
poly(L-lysine)-g-sulfonylurea  0   *Polylysine *Sulfonylurea Compounds. J Control Release 2005 Jun 20;105(1-2):164-76
N-n-pentyl-N'-(2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl)urea  0   *Aniline Compounds *Sulfonylurea Compounds Thromboxane-A Synthase/antagonists & inhibitors Receptors, Thromboxane/antagonists & inhibitors. J Pharmacol Exp Ther 2005 Apr;313(1):293-301
monosulfuron  0   *Pyrimidines *Sulfonylurea Compounds. J Environ Sci (China). 2004;16(5):717-21
SU-118  0   *Coumarins *Sulfonylurea Compounds. J Pharm Sci 2004 Apr;93(4)1039-46
N-(4-chloro-2-mercapto-5-methylbenzenesulphonyl)urea  0   *Sulfonylurea Compounds. Acta Pol Pharm. 1990;47(3-4):45-8
flazasulfuron  0   *Sulfonylurea Compounds. Ecotoxicol Environ Saf. 2003 Jul;55(3):271-7
N-terbutyl-N'-(2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl)urea  0   *Sulfonylurea Compounds Receptors, Thromboxane/antagonists & inhibitors. J Pharmacol Exp Ther 2003 Jul;306(1):59-65
cinosulfuron  94593-91-6   *Sulfonylurea Compounds. Chemosphere 2002 Feb;46(7):953-6
prosulfuron  94125-34-5   *Sulfonylurea Compounds *Triazines. J Agric Food Chem 2002 May 22;50(11):3236-43
N-acetyl-S-(4-chlorophenylcarbamoyl)cysteine  0   *Sulfonylurea Compounds Cysteine/*analogs & derivatives Glutathione Reductase/antagonists & inhibitors. Drug Metab Dispos 2002 Mar;30(3):331-5
S-(4-chlorophenylcarbamoyl)glutathione  0   *Sulfonylurea Compounds Glutathione/*analogs & derivatives Glutathione Reductase/antagonists & inhibitors. Drug Metab Dispos 2002 Mar;30(3):331-5
poly(N-isopropylacrylamide-co-sulfonylurea)  0   *Acrylamides *Sulfonylurea Compounds Biocompatible Materials Pancreas, Artificial. Biosci Biotechnol Biochem 2001 Sep;65(9):2016-20
BM 567  0   *Sulfonylurea Compounds. Bioorg Med Chem Lett 2001 Apr 23;11(8):1019-22
SM 19712  0   *Sulfonamides *Sulfonylurea Compounds. Jpn J Pharmacol 2000 Sep;84(1):7-15
2-((((4,6-dimethoxy-(2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-N,N-dimethyl-3-pyridinecarboxamide  111991-09-4   *Pyridines *Sulfonylurea Compounds Herbicides. Ecotoxicol Environ Saf 2000 Oct;47(2):117-24
thifensulfuron methyl  79277-27-3   *Sulfonylurea Compounds *Thiophenes. J AOAC Int 200 May-Jun;83(3):651-9
flupyrsulfuron  150315-10-9   *Pyrimidines *Sulfonylurea Compounds. J Agric Food Chem 1999 Sep;47(9):3872-8
BM 531  0   *Sulfonylurea Compounds Receptors, Thromboxane/antagonists & inhibitors. Prostaglandins Leukot Essent Fatty Acids 2000 May;62(5):311-7
4-(1-acetoxyethyl)-N-(cyclohexylcarbamoyl)benzenesulfonamide  0   *Sulfonylurea Compounds. Eur J Pharmacol 2000 Feb 18;389(2-3):253-6
BM 500  0   *Sulfonylurea Compounds Receptors, Thromboxane/antagonists & inhibitors. J Pharm Pharmacol 1999 Jun;51(6):695-701
chlorimuron ethyl  90982-32-4   *Pyrimidines *Sulfonylurea Compounds. Biomed Chromatogr 1998 Mar-Apr;12(2):94-6
LY 237868  0   *Sulfonylurea Compounds. Biochim Biophys Acta 1997 Mar 13;1324(2):171-81
BM 27  143214-66-8   *Sulfonylurea Compounds. Epilepsia 1997 Mar;38(3):334-7
hydroxyglimepiride  127554-89-6 3-ethyl-2,5-dihydro-N-(2-(4-(((((4-(hydroxymethyl)cyclohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-4-methyl-2-oxo-1H-pyrrole-1-carboxamide  *Sulfonylurea Compounds. Drug Metabol Drug Interact 1996;13(1):69-85
glisoxepide  25046-79-1   *Sulfonylurea Compounds.
metahexamide  565-33-3   *Sulfonylurea Compounds.
triasulfuron  82097-50-5   *Sulfonylurea Compounds. Bull Environ Contam Toxicol 1995 May;54(5):647-53
LY 219703  0   *Sulfonylurea Compounds. Biochem Pharmacol 1995 Mar 1;49(5):661-8
4-tolylsulfonylurea  1694-06-0   *Sulfonylurea Compounds Toluene/*analogs & derivatives. Drug Metab Dispos Biol Fate Chem 1993 Jul-Aug;21(4):705-9
glibornuride  26944-48-9   *Sulfonylurea Compounds.
Pharma Action Hypoglycemic Agents
methyl bensulfuron  83055-99-6   *Sulfonylurea Compounds. Bull Environ Contam Toxicol 1991;47(1):131
1-(piperidyl)-3-(4-tolylsulfonyl)urea  1443-94-3   *Sulfonylurea Compounds. Jpn J Cancer Res 1990;81(4):324
AHR 12234  125651-31-2 Urea, N'-(2-(diethylamino)ethyl)-N-(3-(diethylamino)propyl)-N-(2-(phenylsulfonyl)ethyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:2)  *Diethylamines *Sulfonylurea Compounds. Arch Int Pharmacodyn Ther 1989;301:131
LY 181984  3955-50-8   *Sulfonylurea Compounds. Cancer Res 1990;50(3):664
4-dextran-sulfonylurea-piretanide  120859-63-4   *Dextrans *Sulfonamides *Sulfonylurea Compounds. Pflugers Arch 1989;413(5):560
4-polyethylene glycol-sulfonylurea-piretanide  120750-70-1   *Polyethylene Glycols *Sulfonamides *Sulfonylurea Compounds. Pflugers Arch 1989;413(5):560
SPC 5002  67514-88-9   *Sulfonylurea Compounds. Acta Pharm Hung 1988;58(4):145
sulofenur  110311-27-8 1H-Indene-5-sulfonamide, N-(((4-chlorophenyl)amino)carbonyl)-2,3-dihydro  *Sulfonylurea Compounds.
Pharma Action Antineoplastic Agents 		Cancer Chemother Pharmacol 1989;23(2):119
glimepiride  93479-97-1   *Sulfonylurea Compounds.
Pharma Action Anti-Arrhythmia Agents ; Hypoglycemic Agents ; Immunosuppressive Agents 		Arzneimittelforschung 1988;38(8):1120DUETACT; GLIMEPIRIDE; AMARYL; AVANDARYL
sulfometuron methyl  74222-97-2   *Sulfonylurea Compounds Acetolactate Synthase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors ; Herbicides 		J Biol Chem 1984;259(14):8753
4-chlorobenzenesulfonylurea  22663-37-2   *Sulfonylurea Compounds. Diabetes Care 1982;5(3):348
HB 180  74680-07-2   *Sulfonylurea Compounds. Res Exp Med (Berl) 1982;180(1):75
glyoxamide  0   *Sulfonylurea Compounds. Probl Endokrinol (Mosk) 1981;27(4):46
chlorcyclamide  19523-45-6 benzenesulfonamide, 4-chloro-N-((2-cyclohexen-1-ylamino)carbonyl)  *Sulfonylurea Compounds. Farmatsiia 1980;29(2):36
metahexamide-isothiocyanate  70324-56-0 Benzenesulfonamide, N-((cyclohexylamino)carbonyl)-3-isothiocyanato-4-methyl  *Sulfonylurea Compounds. Horm Metab Res 11(2):104;1979
glisolamide  24477-37-0 3-isozazolecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl  *Sulfonylurea Compounds. Boll Chim Farm 117(6):348;1978
glyclopyramide  631-27-6 1-(p-chlorobenzenesulfonyl)-3-pyrrolidin-1- ylurea  *Sulfonylurea Compounds. Jpn J Gastroenterol 75(2):239;1978
tosifen  32234-75-6 benzenesulfonamide, 4-methyl-N-(((1-methyl-2-phenylethyl)amino)carbonyl)-, (S)  *Sulfonylurea Compounds. Drug Metab Dispos 6(1):50;1978; Jpn J Pharmacol 27:769;1977
CS 476  41177-35-9 N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2,3-dihydro-7-benzofurancarboxamide  *Sulfonylurea Compounds. Acta Pharmacol Toxicol 41:25;1977
anisilbutamide  24535-67-9 1-butyl-3-(p-methoxyphenylsulfonyl)urea  *Sulfonylurea Compounds. Farmaco(Ed Prat) 31(2):95;1976
gliquidone  33342-05-1 1-cyclohexyl-3-(p-beta-(4,4- dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione- 2-yl)phenethyl)sulfonylurea  *Sulfonylurea Compounds.
Pharma Action Hypoglycemic Agents 		Arzneim Forsch 25(10):1469;1975; Arzneim Forsch 25(9):1455;1975; Arzneim Forsch 27(3):555;1977; Dtsch Med Wochenschr 100(35):1733;1975; Eur J Clin Invest 1979;9(6):411; Med Welt 29(21):897;1978; Med Welt 29(5):191;1978; Munch Med Wochenschr 117(36):1421;1975
glipalamide  37598-94-0 4,5-dihydro-5-methyl-N-((4-methylphenyl)sulfonyl)-1H-pyrazole-1-carboxamide  *Sulfonylurea Compounds. Endocrinol Pol 27(1):37;1976; Pol J Pharmacol Pharm 27(1):45;1975; Pol J Pharmacol Pharm 28(2):129;1976; Pol J Pharmacol Pharm 29(5):469;1977; Pol Tyg Lek 32(39):1501;1977; Pol Tyg Lek 33(40):1583;1978
glypentide  32797-92-5 N-(4-(beta-o-anisamidoethyl)benzenesulfonyl)-N'-cyclopentylcarbamide  *Sulfonylurea Compounds. Arch Pharmacol Toxicol 2(2):115;1976; Arzneim Forsch 27(4):852;1977; Biochem Pharmacol 23(20):2922;1974; Curr Ther Res 21(1):50;1977; Diabete Metab 4(3):181;1978; Rev Iber Endocrinol 21(125):427;1974; Rev Iber Endocrinol 23(134):181;1976
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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