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Tetrazoles

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Definition:      
Examples Cefotetan; Losartan; Tetrazolium Salts
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(3,4,5-trimethoxyphenyl)-5-(4-ethoxyphenyl)-1H-tetrazole  0   *Tetrazoles. J Med Chem. 2012 Jan 12;55(1):475-88.
5-(2-(2-(2-cyanopyrrolidin-1-yl)-2-oxoethylamino)propyl)-5-(1H-tetrazol-5-yl)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene-2,8-dicarboxylic acid bisdimethylamide  0   *Dibenzocycloheptenes *Tetrazoles Dipeptidyl-Peptidase IV Inhibitors. Xenobiotica. 2011 Nov;41(11):945-57.
5-(pentadec-8-enyl)-2H-tetrazole  0   *Tetrazoles. Antimicrob Agents Chemother. 2011 Aug;55(8):3691-5.
ethyl(5-((3-acetyl-1H-indol-1-yl)methyl)-2H-tetrazol-2-yl)acetate  0   *Indoles *Tetrazoles Anti-Infective Agents. Arch Pharm Res. 2011 Jul;34(7):1085-96
1-(1-(2H-tetrazol-5-ylmethyl)-1H-indol-3-yl)ethanone  0   *Indoles *Tetrazoles Anti-Infective Agents. Arch Pharm Res. 2011 Jul;34(7):1085-96
N-(2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl)-N-isobutylpentanamide  0   *Tetrazoles. J Pharm Biomed Anal 2011 Aug 25;56(1):16-22
(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid  0   *Acetic Acids *Tetrazoles Stearoyl-CoA Desaturase/antagonists & inhibitors. J Med Chem 2011 Jul 28;54(14):5082-96
5-(1H-tetrazol-1-yl)-1,2,4-triazole  0   *Tetrazoles *Triazoles. J Phys Chem A. 2011 Jun 9;115(22):5693-707
fimasartan  247257-48-3   *Biphenyl Compounds *Pyrimidines *Tetrazoles. Int J Clin Pharmacol Ther. 2011 May;49(5):321-7
2,4,6-tris(1-phenyl-1H-tetrazolylsulfanylmethyl)mesitylene  0   *Benzene Derivatives *Tetrazoles. Chemistry. 2011 Feb 11;17(7):2189-98
1-(3-methoxyphenyl)-4-methyl-1H-tetrazole-5(4H)-thione  0   *Tetrazoles *Thiones. J Org Chem. 2011 Jan 7;76(1):216-22
1-methyl-4-phenyl-1H-tetrazole-5(4H)-thione  0   *Tetrazoles *Thiones. J Org Chem. 2011 Jan 7;76(1):216-22
1-(tetrazol-5-yl)ethanol  0   *Tetrazoles Ethanol/*analogs & derivatives. J Phys Chem A. 2010 Dec 23;114(50):13076-85
AM 6701  0   *Tetrazoles. Mol Biosyst 2010 Aug;6(8):1381-8
PF152 compound  0   *Pyrimidines *Tetrazoles Matrix Metalloproteinase 13/antagonists & inhibitors. Arthritis Rheum. 2010 Oct;62(10):3006-15
Tribenzor  0   *Hydrochlorothiazide *Imidazoles *Tetrazoles *Amlodipine Drug Combinations Hypertension/drug therapy. Med Lett Drugs Ther. 2010 Sep 6;52(1346):70-1TRIBENZOR; OLMESARTAN MEDOXOMIL; HYDROCHLOROTHIAZIDE
6-(4-chlorophenoxy)tetrazolo(5,1-a)phthalazine  0   *Phthalazines *Tetrazoles. Pharmacol Rep 2010 Mar-Apr;62(2):273-7
NS13558  0   *Tetrazoles. Naunyn Schmiedebergs Arch Pharmacol. 2010 Mar;381(3) (dup#1):271-83
3-(1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl)propionate-3'-methyl-2'-(pentanoyl(2'-(tetrazol-5-ylate)biphenyl-4'-ylmethyl)amino)butyrate  0   *Aminobutyric Acids *Tetrazoles Receptors, Angiotensin/antagonists & inhibitors Neprilysin/antagonists & inhibitors. Lancet 2010 Apr 10;375(9722):1255-66
Exforge HCT  0   *Hydrochlorothiazide *Tetrazoles *Amlodipine Drug Combinations Valine/*analogs & derivatives. Am J Cardiovasc Drugs. 2009;9(6):411-8EXFORGE HCT; VALSARTAN; HYDROCHLOROTHIAZIDE; VALSARTAN AND HYDROCHLOROTHIAZIDE
3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-hydroxymethyloxazolidin-2-one  0   *Tetrazoles *Oxazolidinones. Antimicrob Agents Chemother 2008 Dec;52(12):4442-7
A-839977  0   *Pyridines *Tetrazoles. Behav Brain Res. 2009 Dec 1;204(1):77-81
3,6-bis(1H-1,2,3,4-tetrazol-5-ylamino)-1,2,4,5-tetrazine  0   *Tetrazoles. J Hazard Mater. 2009 Oct 15;170(1):306-13
1-(3,5-bis-trifluoromethylphenyl)-3-(2,4-dibromo-6-(1H-tetrazol-5-yl)phenyl)urea  0   *Phenylurea Compounds *Tetrazoles. Cardiovasc Res 2009 Mar 1;81(4):686-94
5-(pyrrolidin-2-yl)tetrazole  0   *Pyrrolidines *Tetrazoles. Angew Chem Int Ed Engl. 2009;48(15):2699-702
alpha-amino phenylalanine tetrazole  0   *Benzylamines *Tetrazoles. J Sep Sci 2008 Sep;31(16-17):3002-8
((E)-(1-(4-ethoxyphenyl)-1H-tetrazol-5-yl)iminomethyl)dimethylamine  0   *Methylamines *Tetrazoles. Acta Crystallogr C. 2008 Aug;64(Pt 8):o414-6
1-(4-nitrophenyl)-1H-tetrazol-5-amine  0   *Amines *Tetrazoles. Acta Crystallogr C. 2008 Aug;64(Pt 8):o414-6
3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopentapyrazole  0   *Pyrazoles *Tetrazoles. J Med Chem 2008 Aug 28;51(16):5101-8
1,3-bis(tetrazol-5-yl)triazenate  0   *Tetrazoles *Triazines. Chemistry. 2008;14(12):3727-36
amlodipine, valsartan drug combination  0   *Tetrazoles *Amlodipine Drug Combinations.
Pharma Action Antihypertensive Agents 		Drugs 2008;68(3):373-81EXFORGE
pratosartan  153804-05-8   *Imidazoles *Tetrazoles. Hypertens Res 2008 Feb;31(2):281-7
HBF 0259  0   *Pyrimidines *Tetrazoles. Antimicrob Agents Chemother 2007 Dec;51(12):4427-37
PF 376304  0   *Pyrimidines *Tetrazoles. Chem Res Toxicol 2007 Dec;20(12):1871-7
4-(hydroxybutyl)carbamic acid 2-(5-(1-(2-amino-2-methylpropionylamino)-2-benzyloxyethyl)tetrazol-1-yl)ethyl ester  0   *Carbamates *Tetrazoles. J Med Chem 2007 Nov 29;50(24):5890-3
5-(5-nitropyridin-2-yldithio)-1-phenyl-1H-tetrazole  0   *Pyridines *Tetrazoles. Acta Crystallogr C. 2007 Oct;63(Pt 10):o606-8
1-(3,5-bis(trifluoromethyl)phenyl)-3-(4-bromo-2-(1H-tetrazol-5-yl)phenyl)thiourea  0   *Tetrazoles Thiourea/*analogs & derivatives. Mol Pharmacol 2007 Oct;72(4):1033-44
1-benzyl-3-pentyl-2-(6-(1H-tetrazol-5-ylmethoxy)naphthalen-2-yl)-1H-indole  0   *Indoles *Tetrazoles Plasminogen Activators/antagonists & inhibitors. Mol Pharmacol 2007 Oct;72(4):897-906
5-n-butyl-4-(4-(2-(1H-tetrazol-5-yl)-1H-pyrrol-1-yl)phenylmethyl)-2,4-dihydro-2-(2,6-dichlorophenyl)-3H-1,2,4-triazol-3-one  0   *Tetrazoles *Triazoles Receptor, Angiotensin, Type 1. Biomed Chromatogr 2007 Sep;21(9):912-24
A-438079  0   *Pyridines *Tetrazoles. Neuroscience 2007 Jun 8;146(4):1817-28
(2R,3R,4S,5R)-2-(6-amino-2-(((1S)-2-hydroxy-1-(phenylmethyl)ethyl)amino)-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol  0   *Purines *Tetrazoles. Eur J Pharmacol 2007 Jun 14;564(1-3):219-25
5-ethoxy-1-phenyl-1H-tetrazole  0   *Tetrazoles. J Phys Chem A 2007 Apr 19;111(15):2879-88
4-oxo-4H-chromene-2-carboxylic acid (2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl)-phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)amide  0   *Benzopyrans *Isoquinolines *Tetrazoles P-Glycoprotein/antagonists & inhibitors. Rapid Commun Mass Spectrom. 2006;20(9):1457-62
2-amino-3-(3-hydroxy-5-(2-benzyl-2H-5-tetrazolyl)-4-isoxazolyl)propionic acid  0   *Tetrazoles alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/*analogs & derivatives Receptors, AMPA/agonists. J Med Chem 2007 May 17;50(10):2408-14
3,4-dehydrocilostazol  0   *Tetrazoles. Anal Bioanal Chem 2006 Feb;384(3):780-90
(2-fluoromethoxy-5-(5-trifluoromethyltetrazol-1-yl)benzyl)(2-phenylpiperidin-3-yl)amine  0   *Piperidines *Tetrazoles Fluorine Radioisotopes Receptors, Neurokinin-1/antagonists & inhibitors. J Nucl Med 2007 Jan;48(1):100-7
DA 7157  0   *Oxazoles *Tetrazoles. Antimicrob Agents Chemother 2006 Sep;50(9):3170-2
3-(5-(2,3-dichlorophenyl)tetrazol-1-ylmethyl)pyridine  0   *Pyridines *Tetrazoles. J Med Chem 2006 Jun 15;49(12):3659-66
GW78415X  0   *Morpholines *Tetrazoles. Immunol Res 2005;33(3):213-21
2-methylsulfanyl-3-(2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl)-3H-quinazolin-4-one  0   *Quinazolines *Tetrazoles Receptors, Angiotensin/antagonists & inhibitors. J Med Chem 2006 Mar 9;49(5):1526-35
N-tetrazol-5-yl-9-oxo-9H-xanthene-2-sulfonamide  0   *Tetrazoles *Xanthones. J Med Chem 2006 Feb 23;49(4):1282-90
LY2318912  0   *Tetrazoles. Proc Natl Acad Sci U S A 2005 Dec 6;102(49):17852-7
fentrazamide  0   *Tetrazoles. Bull Environ Contam Toxicol 2005 Apr;74(4):667-72
2-4-(3-(1H-1,2,3,4-tetraazol-5-yl)propoxy)phenethyl-1,3-isoindolinedione  0   *Tetrazoles *Isoindoles. Eur J Pharmacol. 2005 Mar 28;511(2-3):219-27
KP372-1  0   *Heterocyclic Compounds with 4 or More Rings *Tetrazoles Stereoisomerism. Br J Cancer 2005 May 23;92(10):1899-905
(5,6,7,8-tetrahydronaphthalen-1-yl)-(2-(1H-tetrazol-5-yl)phenyl)amine  0   *Tetrahydronaphthalenes *Tetrazoles. J Pharmacol Exp Ther 2005 Apr;313(1):250-9
2-butyl-6-hydroxy-3-(2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl)-3H-quinazolin-4-one  0   *Quinazolines *Tetrazoles. J Med Chem 2005 Mar 10;48(5):1630-7
N-(3-bromophenyl)-N'-(4-bromo-2-(1H-tetrazol-5-yl)phenyl)urea  0   *Phenylurea Compounds *Tetrazoles Chloride Channels/antagonists & inhibitors. Am J Pathol 2005 Feb;166(2):467-76
N-(3,5-dichlorophenyl)-N'-(2-(1H-tetrazol-5-yl)biphenyl-4-yl-4'-carboxylic acid dimethylamide)urea  0   *Tetrazoles *Phenylurea Compounds Chloride Channels/antagonists & inhibitors. Am J Pathol 2005 Feb;166(2):467-76
3-(3-fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl)-4-methylpyridine  0   *Pyridines *Tetrazoles. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5477-80
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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