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Thiamine Pyrophosphate

More information in Books or onNLM PubMed
Definition: The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.  do not confuse with THIAMINE PYROPHOSPHATASE; deficiency: coordinate THIAMINE PYROPHOSPHATE /defic (IM) with THIAMINE DEFICIENCY (IM)   
Pharmacological Action Vitamin B Complex 		Other names Thiamine Diphosphate; Cocarboxylase; Pyrophosphate, Thiamine; Berolase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
adenine thiamine diphosphate  0   Adenine/*analogs & derivatives Thiamine Pyrophosphate/*analogs & derivatives. FEBS J 2009 Jun;276(12):3256-68
acryloylthiamine diphosphate  0   Thiamine Pyrophosphate/*analogs & derivatives. J Am Chem Soc 2007 Dec 26;129(51):15750-1
C2-alpha-lactylthiamin diphosphate  0   Thiamine Pyrophosphate/*analogs & derivatives. J Biol Chem 2004 Dec 24;279(52):54312-8
hydroxyethylidene-thiamine pyrophosphate  0   Thiamine Pyrophosphate/*analogs & derivatives. Science 2001 Dec 21;294(5551):2489-90
2'-methoxythiamine pyrophosphate  0   Thiamine Pyrophosphate/*analogs & derivatives. Bioorg Med Chem Lett 2001 Sep 3;11(17):2245-8
dihydroxyethylthiamine pyrophosphate  0   Thiamine Pyrophosphate/*analogs & derivatives. Biochem Mol Biol Int 1995 Jan;35(1):111-5
2-acetylthiamine pyrophosphate  104114-88-7   Thiamine Pyrophosphate/*analogs & derivatives. Biochemistry 1986;25(20):6036
2-(1-hydroxyethyl)thiamine pyrophosphate  20319-27-1   Thiamine Pyrophosphate/*analogs & derivatives. Biochem Int 1985;11(4):509
tetrahydrothiamine pyrophosphate  35728-83-7   Thiamine Pyrophosphate/*analogs & derivatives. Biochemistry 1983;22(1):150
thiamine thiothiazolone pyrophosphate  59733-98-1 Diphosphoric acid, mono(2-(3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-2,3-dihydro-4-methyl-2-thioxo-5-thiazolyl)ethyl) ester  Thiamine Pyrophosphate/*analogs & derivatives Pyruvate Dehydrogenase Complex/antagonists & inhibitors. Biochem J 1981;195(3):715
cytochrome C, flavin mononucleotide, thiamine pyrophosphate drug combination  0   *Flavin Mononucleotide *Thiamine Pyrophosphate *Cytochromes c Drug Combinations. Brain Nerve 30(6):609;1978
thiamine thiazolone pyrophosphate  59733-97-0 Diphosphoric acid, mono(2-(3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-2,3-dihydro-4-methyl-2-oxo-5-thiazolyl)ethyl) ester  Thiamine Pyrophosphate/*analogs & derivatives. Biochem Biophys Res Commun 74(4):1667;1977; J Biol Chem 1980;255(8):3302; Proc Natl Acad Sci USA 75(10):4877;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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