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Thiolester Hydrolases

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Definition:      
Examples Acetyl-CoA Hydrolase; Palmitoyl-CoA Hydrolase; Ubiquitin Thiolesterase 		Other names Hydrolases, Thiolester
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Apt1 protein, Drosophila  EC 3.1.2.-   *Thiolester Hydrolases *Drosophila Proteins. Fly (Austin) 2008 Jul-Aug;2(4):198-214
YOD1 protein, human  EC 3.1.2.-   *Thiolester Hydrolases. Mol Cell 2009 Oct 9;36(1):28-38
Acot13 protein, mouse  EC 3.1.2.-   *Thiolester Hydrolases. Biochem J 2009 Jul 15;421(2):311-22
FadM protein, E coli  EC 3.1.2.-   *Thiolester Hydrolases *Escherichia coli Proteins. J Bacteriol 2009 Oct;191(20):6320-8
Usp30 protein, human  EC 3.1.2.15   *Thiolester Hydrolases *Mitochondrial Proteins Endopeptidases. Mol Biol Cell 2008 May;19(5):1903-11
YbdB protein, E coli  EC 3.1.2.-   *Thiolester Hydrolases *Escherichia coli Proteins. J Bacteriol 2007 Oct;189(19):7112-26
Usp22 protein, human  EC 3.1.2.15   *Thiolester Hydrolases. Mol Cell 2008 Jan 18;29(1):92-101
ACOT13 protein, human  EC 3.1.2.-   *Thiolester Hydrolases. Biochem Biophys Res Commun 2006 Oct 13;349(1):172-7
YeiG protein, E coli  EC 3.1.2.12   *Thiolester Hydrolases *Escherichia coli Proteins. J Biol Chem 2006 May 19;281(20):14514-22
FrmB protein, E coli  EC 3.1.2.12   *Thiolester Hydrolases *Escherichia coli Proteins. J Biol Chem 2006 May 19;281(20):14514-22
USP42 protein, human  EC 3.1.2.15   *Thiolester Hydrolases. Leukemia 2006 Feb;20(2):210-1
OTUB2 protein, human  EC 3.1.2.-   *Thiolester Hydrolases Neoplasm Proteins. EMBO Rep. 2004 Aug;5(8):783-8
FATB1 protein, Arabidopsis  EC 3.1.2.-   *Thiolester Hydrolases *Arabidopsis Proteins Acyl Carrier Protein.
srfA4 protein, Bacillus subtilis  EC 3.1.2.-   *Bacterial Proteins *Thiolester Hydrolases.
YLR118C protein, S cerevisiae  EC 3.1.2.-   *Thiolester Hydrolases *Saccharomyces cerevisiae Proteins.
CYK-3 protein, C elegans  EC 3.1.2.-   *Thiolester Hydrolases *Caenorhabditis elegans Proteins. J Cell Sci 2002 Jun 1;115(Pt 11):2293-302
CTE-1 protein, mouse  EC 3.1.2.14   *Thiolester Hydrolases. J Biol Chem 2002 Feb 1;277(5):3424-32
4,8-dimethylnonanoyl-CoA thioesterase  EC 3.1.2.-   *Thiolester Hydrolases. Biochem Biophys Res Commun 2002 Jan 18;290(2):629-34
acyl-coA hydrolase D1  EC 3.1.2.20   *Thiolester Hydrolases. Arch Biochem Biophys 2001 May 15;389(2):245-53
Uchl4 protein, mouse  EC 3.1.2.-   *Thiolester Hydrolases Nerve Tissue Proteins. Biochem Biophys Res Commun. 2001 May 11;283(3):627-33
bile acid-coenzyme A thioesterase  EC 3.1.2.-   *Thiolester Hydrolases. J Lipid Res 2000 Jul;41(7):1154-62
ACOT2 protein, human  EC 3.1.2.2   *Thiolester Hydrolases. Biochem Biophys Res Commun 2000 Aug 18;275(1):233-40
DltD protein, bacteria  EC 3.1.2.-   *Bacterial Proteins *Thiolester Hydrolases. J Bacteriol 2000 May;182(10):2855-64
LYPLA1 protein, human  EC 3.1.2.-   *Thiolester Hydrolases. J Biol Chem 1999 Nov 12;274(46):33148-54
tesA protein, E coli  EC 3.1.1.-   *Lysophospholipase *Escherichia coli Proteins *Periplasmic Proteins Endopeptidases Thiolester Hydrolases. J Biochem (Tokyo) 1999 Aug;126(2):445-8
bile acid-CoA hydrolase  EC 3.1.2.-   *Bacterial Proteins *Thiolester Hydrolases. J Lipid Res 1999 Jan;40(1):17-23
ubiquitin C-terminal hydrolase 8  EC 3.1.2.-   *Isoenzymes *Thiolester Hydrolases. Biochem J 1997 Jul 15;325( Pt 2):325-30
2-ketocyclohexanecarboxyl-coenzyme A hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Proc Natl Acad Sci U S A 1997 Jun 10;94(12):6484-9
USP11 protein, human  EC 3.1.2.15   *Thiolester Hydrolases Eye Proteins. Hum Mol Genet 1996 Apr;5(4):533-8
FatB2 protein, Cuphea palustris  EC 3.1.2.-   *Plant Proteins *Thiolester Hydrolases. Plant Physiol 1996 Jan;110(1):203-10
palmitoyl-protein thioesterase  EC 3.1.2.22   *Thiolester Hydrolases. Methods Enzymol 1995;250:336-47
4-hydroxybenzoyl-CoA hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Biodegradation 1994 Dec;5(3-4):259-76
cmaT protein, Pseudomonas syringae  EC 3.1.2.-   *Bacterial Proteins *Thiolester Hydrolases. J Bacteriol 1994 Dec;176(24):7574-86
grsT protein, Bacillus brevis  125752-30-9   *Bacterial Proteins *Thiolester Hydrolases. J Bacteriol 1989;171(10):5422
propionyl CoA hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Biochim Biophys Acta 1989;1005(1):13
clofibroyl-CoA hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Biochim Biophys Acta 1987;918(1):60
succinyl-CoA hydrolase  EC 3.1.2.3   *Thiolester Hydrolases. J Bacteriol 1985;163(3):1126
thioesterase B  EC 3.1.2.-   *Thiolester Hydrolases. Arch Biochem Biophys 1985;237(1):208
(S)-methylmalonyl-CoA hydrolase  EC 3.1.2.17   *Thiolester Hydrolases. J Biol Chem 1983;258(18):11415
3-hydroxyisobutyryl-CoA hydrolase  EC 3.1.2.4   *Thiolester Hydrolases. Pediatrics 1982;70(4):532
octanyl-CoA hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Arch Biochem Biophys 1981;211(2):599
hydroxymethylgutaryl-CoA hydrolase  EC 3.1.2.5   *Thiolester Hydrolases. Biochim Biophys Acta 1981;666(1):181
3-hydroxybutyryl CoA deacylase  EC 3.1.2.-   *Thiolester Hydrolases. Arch Biochem Biophys 1980;205(1):94
acetylcarnitine hydrolase  EC 3.1.2.- carnitine acetyl-CoA hydrolase  *Thiolester Hydrolases. Biochem J 152:167;1975
acetoacetyl-CoA hydrolase  EC 3.1.2.11   *Thiolester Hydrolases. Biochem J 130(3);785:1972; Biochem Soc Trans 6(1):126;1978
thiolacetic acid hydrolases  EC 3.1.2.-   *Thiolester Hydrolases. Br J Exp Pathol 56(6):495;1975
thioesterase II  EC 3.1.2.-   *Fatty Acid Synthetase Complex *Thiolester Hydrolases. J Biol Chem 254(18):8932;1979; J Dairy Sci 1980;63(2):337
S-succinylglutathione hydrolase  EC 3.1.2.13   *Thiolester Hydrolases. J Biol Chem 254(15):7024;1979
phenylacetyl Coenzyme A hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Methods Enzymol 43:482;1975
methylthioadenosine hydrolase  EC 3.1.2.-   *Thiolester Hydrolases. Biochem Biophys Res Commun 78(4):1273;1977
hydroxyacylglutathione hydrolase  EC 3.1.2.6   *Thiolester Hydrolases. Biochim Biophys Acta 1979;580(2):277; Biochim Biophys Acta 1980;611(1):168; Experientia 32(11):1382;1976; Int J Biochem 9(11):853;1978; J Chromatogr 116(1):225;1975; Neoplasma 25(4):465;1978
s-formylglutathione hydrolase  EC 3.1.2.12   *Thiolester Hydrolases Arabidopsis Proteins. Biochim Biophys Acta 1980;611(2):323; J Biol Chem 249(23):7664;1974
citrate (pro-3S)-lyase deacetylase  EC 3.1.2.-   *Thiolester Hydrolases. J Bacteriol 124(3):1052;1975
oleoyl-(acyl-carrier-protein) hydrolase  EC 3.1.2.14   *Thiolester Hydrolases. Arch Biochem Biophys 189(2):382;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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