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Tolazoline

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Definition: A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.     
Pharmacological Action Adrenergic alpha-Antagonists; Antihypertensive Agents; Vasodilator Agents 		Other names Benzalolin; Tolazoline Monohydrochloride; Tolazoline Hydrochloride; Priscoline; Priscol; Pridazole; Novartis Brand of Tolazoline Hydrochloride; Divascol; Ciba Vision Brand of Tolazoline HydrochlorideDrugs* : PRISCOLINE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(4'-isothiocyanatobenzyl)imidazoline  130262-94-1   Tolazoline/*analogs & derivatives. Eur J Pharmacol 1991;199(3):315
2-(4'-aminobenzyl)imidazoline  13623-47-7   Tolazoline/*analogs & derivatives. Eur J Pharmacol 1991;199(3):315
alpha-hydroxymethyltolazoline  109055-32-5   Tolazoline/*analogs & derivatives. Naunyn Schmiedebergs Arch Pharmacol 1987;335(4):391
Reboul cocktail  117706-64-6   *Lidocaine *Penicillins *Tetracyclines *Tolazoline Drug Combinations. J Mal Vasc 1986;11(4):388
2-(3,4-dihydroxybenzyl)imidazoline  72143-18-1   Tolazoline/*analogs & derivatives. J Med Chem 1983;26(7):957
2-(3,4,alpha-trihydroxybenzyl)imidazoline  85232-93-5   Tolazoline/*analogs & derivatives. J Med Chem 1983;26(7):957
SR 82 tablets  85099-49-6 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl-, mixt. with 4,5-dihydro-2-(phenylmethyl)-1H-imidazole and N-methyl-N-(2-phenylethyl)benzeneethanamine  *Phenethylamines *Phenobarbital *Tolazoline Drug Combinations. Pharmazie 1982;37(10):737

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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