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Tosyllysine Chloromethyl Ketone

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Definition: An inhibitor of SERINE ENDOPEPTIDASES. Acts as an alkylating agent and is known to interfere with the translation process.     
Pharmacological Action Alkylating Agents; Protein Synthesis Inhibitors; Serine Proteinase Inhibitors 		Other names Tosyllysyl Chloromethane; TLCK; Chlorotosylamidoaminoheptanone; Ketone, Tosyllysine Chloromethyl; Chloromethyl Ketone, Tosyllysine; Chloromethane, Tosyllysyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tosyllysine chloromethyl ketone-thrombin  0   *Thrombin Tosyllysine Chloromethyl Ketone/*analogs & derivatives. J Biol Chem 1986;261(34):15928

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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