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Tosylphenylalanyl Chloromethyl Ketone

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Definition: An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.     
Pharmacological Action Alkylating Agents; Protein Synthesis Inhibitors; Serine Proteinase Inhibitors 		Other names Tosylphenylalanyl Chloromethane; Chlorophenyltosylamidobutanone; TPCK; Ketone, Tosylphenylalanyl Chloromethyl; Chloromethyl Ketone, Tosylphenylalanyl; Chloromethane, Tosylphenylalanyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone  0   Tosylphenylalanyl Chloromethyl Ketone/*analogs & derivatives. J Neurochem 2001 Apr;77(2):466-75

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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