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Antipsychotic Agents

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Definition: Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.  note entry term ANTIPSYCHOTIC EFFECT: use only for the antipsychotic effect of a chemical substance   
See Also Dopamine Antagonists
Other names Tranquilizing Agents, Major; Neuroleptics; Tranquilizers, Major; Major Tranquillizing Agents; Major Tranquilizing Agents; Effects, Antipsychotic; Effect, Antipsychotic; Drugs, Neuroleptic; Drugs, Antipsychotic; Agents, Neuroleptic; Agents, Major Tranquillizing; Agents, Major Tranquilizing; Agents, Antipsychotic; Tranquillizing Agents, Major; Neuroleptic Drugs; Neuroleptic Agents; Major Tranquilizers; Antipsychotics; Antipsychotic Effects; Antipsychotic Effect
Substances having this pharmacologic action: stepholidine; fluphenazine enanthate; fencamfamine; zotepine; timiperone; clopenthixol decanoate; DN 1417; nemonapride; Ro 22-1319; haloperidol decanoate; sulforidazine; fluperlapine; metylperon; Raclopride; fluanisone; pipamperone; bromperidol; Pimozide; Chlorpromazine; Chlorprothixene; Benperidol; Clopenthixol; Clozapine; Lithium; Azaperone; Prochlorperazine; Promazine; Reserpine; Spiperone; Sulpiride; Thioridazine; Thiothixene; Ritanserin; Trifluoperazine; Trifluperidol; Triflupromazine; Ondansetron; Remoxipride; Tiapamil Hydrochloride; Risperidone; Loxapine; Penfluridol; Mesoridazine; Methiothepin; Methotrimeprazine; Flupenthixol; Fluphenazine; Fluspirilene; Droperidol; Perazine; Perphenazine; Haloperidol; Acepromazine; Butaclamol; Molindone; Etazolate; fluphenazine depot; sultopride; SK&F 10047; dixyrazine; tetrahydropalmatine; amitriptyline, perphenazine drug combination; piflutixol; isofloxythepin; zetidoline; veralipride; Asenapine; SR 142801; ziprasidone; aripiprazole; 3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine; dicarbine; 9-hydroxy-risperidone; DuP 734; N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride; clothiapine; quetiapine; fananserin; olanzapine; clopenthixol acetate ester; 3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol; perospirone; sertindole; dapiprazole; rimcazole; Sch 39166; amperozide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bifeprunox  0 1-(2-Oxo-benzoxazolin-7-yl)-4-(3-biphenyl)methylpiperazinemesylate  *Benzoxazoles *Piperazines Antipsychotic Agents. J Pharmacol Exp Ther 2005 Oct;315(1):265-72
cyamemazine  3546-03-0   *Phenothiazines Antipsychotic Agents Anti-Anxiety Agents Photosensitizing Agents. Lancet 1981;1(8216):386; Therapie 30(2):267;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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