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Transcription Factors

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Definition: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.  in genetic transcription; /biosyn /physiol permitted; regulatory proteins go here or under REPRESSOR PROTEINS or VIRAL REGULATORY PROTEINS   
See Also Trans-Activators
Examples Adenovirus E1A Proteins; Adenovirus E1B Proteins; Antennapedia Homeodomain Protein; AraC Transcription Factor; Basic Helix-Loop-Helix Transcription Factors; Basic-Leucine Zipper Transcription Factors; beta Catenin; BRCA1 Protein; Core Binding Factors; Cyclic AMP Receptor Protein; E2F Transcription Factors; Early Growth Response Transcription Factors; Erythroid-Specific DNA-Binding Factors; Fushi Tarazu Transcription Factors; G-Box Binding Factors; GATA Transcription Factors; Goosecoid Protein; Hepatocyte Nuclear Factors; Host Cell Factor C1; I-kappa B Proteins; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Inhibitor of Differentiation Proteins; Interferon Regulatory Factors; Interferon-Stimulated Gene Factor 3; Kruppel-Like Transcription Factors; Leucine-Responsive Regulatory Protein; MADS Domain Proteins; MSX1 Transcription Factor; Myeloid-Lymphoid Leukemia Protein; NF-kappa B; NFATC Transcription Factors; NFI Transcription Factors; Nuclear Factor 90 Proteins; Nuclear Receptor Coactivators; Nuclear Respiratory Factors; Onecut Transcription Factors; Otx Transcription Factors; p300-CBP Transcription Factors; Paired Box Transcription Factors; POU Domain Factors; Proto-Oncogene Proteins c-bcl-6; Proto-Oncogene Proteins c-ets; Proto-Oncogene Proteins c-myb; Proto-Oncogene Proteins c-rel; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; Receptors, Notch; Repressor Proteins; Rho Factor; Sigma Factor; Smad Proteins; SOX Transcription Factors; STAT Transcription Factors; T-Box Domain Proteins; TCF Transcription Factors; Trans-Activators; Transcription Factor AP-2; Transcription Factor DP1; Transcription Factors, General; Transcriptional Elongation Factors; Tristetraprolin; Winged-Helix Transcription Factors 		Other names Factors, Transcription; Factor, Transcription; Transcription Factor
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VAX1 protein, human  0   *Transcription Factors *Homeodomain Proteins. Development. 2011 Mar;138(5):873-8.
LST8 protein, rat  0   *Transcription Factors Protein Subunits. Cell Death Differ. 2012 Feb;19(2):310-20.
NSL1 protein, Drosophila  0   *Transcription Factors *Drosophila Proteins DNA-Binding Proteins. Nucleic Acids Res. 2012 Feb;40(4):1509-22.
Dlx3 protein, Xenopus  0   *Transcription Factors *Xenopus Proteins Homeodomain Proteins. Nucleic Acids Res. 1999 Feb 1;27(3):764-70.
Lhx9 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins LIM-Homeodomain Proteins. PLoS Biol. 2011 Dec;9(12):e1001218.
NUP98-PSIP1 fusion protein, human  0   *Oncogene Proteins, Fusion *Nuclear Pore Complex Proteins *Adaptor Proteins, Signal Transducing Transcription Factors. Leuk Res. 2011 Jun;35(6):e75-6.
myelin gene regulatory factor, mouse  0   *Transcription Factors. Cell. 2009 Jul 10;138(1):172-85.
MDT-15 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Protein Subunits Mediator Complex. PLoS One. 2011;6(11):e28036.
Torc1 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2021-6
TORC1 protein, Drosophila  0   *Transcription Factors *Drosophila Proteins. Dev Cell. 2012 Jan 17;22(1):172-82
ZNF750 protein, human  0   *Transcription Factors Zinc Fingers. BMC Med Genet. 2011;12() (dup#107):167
MTF2 protein, human  0   *Transcription Factors.
VNI2 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Plant Cell. 2011 Jun;23(6):2155-68.
Grhl2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins. Development. 2012 Feb;139(3):525-36.
Creb3l2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins DNA-Binding Proteins. Dis Model Mech. 2011 Nov;4(6):763-76.
zinc finger protein 132 protein, human  0   *DNA-Binding Proteins *Transcription Factors Zinc Fingers. Int J Cancer. 2012 Feb 15;130(4):885-95
Cbf12 protein, S pombe  0   *Transcription Factors *Schizosaccharomyces pombe Proteins. PLoS One. 2011;6(8):e23650.
Cbf11 protein, S pombe  0   *Transcription Factors *Schizosaccharomyces pombe Proteins. PLoS One. 2011;6(8):e23650.
Oaz protein, Xenopus  0   *Transcription Factors *Xenopus Proteins DNA-Binding Proteins Zinc Fingers. PLoS One. 2011;6(8):e22621.
ZNF511-PRAP1 protein, human  0   *Transcription Factors Zinc Fingers. Mol Ther. 2011 Aug;19(8):1478-86
Gal80 protein, zebrafish  0   *DNA-Binding Proteins *Transcription Factors *Zebrafish Proteins. Dev Dyn. 2011 Oct;240(10):2324-34
ZNF206 protein, human  0   *Transcription Factors Zinc Fingers. Stem Cells. 2007 Sep;25(9):2173-82.
Ftf1 protein, Fusarium oxysporum  0   *Fungal Proteins *Transcription Factors Virulence/genetics. Phytopathology. 2011 Apr;101(4):470-9
CNOT3 protein, mouse  0   *Transcription Factors. EMBO J. 2011 Nov 16;30(22):4678-91
Lsy-27 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins Zinc Fingers. Genetics. 2011 Jul;188(3):753-9.
RAP2.12 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Nature. 2011 Nov 17;479(7373):419-22
HOMEZ protein, Xenopus  0   *Transcription Factors *Homeodomain Proteins *Xenopus Proteins Zinc Fingers Leucine Zippers. Biochem Biophys Res Commun. 2011 Nov 11;415(1):11-6
myocardin-related transcription factor-B, rat  0   *Transcription Factors. J Invest Dermatol. 2011 Dec;131(12):2378-85
zinc finger protein 577, human  0   *DNA-Binding Proteins *Transcription Factors Zinc Fingers. J Clin Pathol. 2011 Nov;64(11):1010-3
Nob1 protein, rat  0   *Carrier Proteins *Transcription Factors. Neurosci Lett. 2011 Mar 10;491(1):79-82.
ANAC078 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Plant Cell Physiol. 2009 Dec;50(12):2210-22.
Hsf2 protein, rat  0   *Heat-Shock Proteins *Transcription Factors. J Neurosci. 1996 Jan 15;16(2):478-85.
Arid3c protein, mouse  0   *Transcription Factors. Mol Immunol. 2011 Oct;49(1-2):260-72.
ARID3C protein, human  0   *Transcription Factors. Mol Immunol. 2011 Oct;49(1-2):260-72.
TORC3 protein, rat  0   *Transcription Factors. J Neuroendocrinol. 2011 Aug;23(8):754-66
ERF71 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Biochem Biophys Res Commun. 2011 Oct 14;414(1):135-41.
ANAC071 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16128-32.
irx3b protein, Danio rerio  0   *Transcription Factors *Homeodomain Proteins *Zebrafish Proteins. Dev Dyn. 2011 Aug;240(8);2011-27
NHR-23 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins. Biochem Biophys Res Commun. 2011 Oct 7;413(4):515-20.
Npa3 protein, S cerevisiae  0   *Transcription Factors *Saccharomyces cerevisiae Proteins. J Biol Chem. 2011 Oct 14;286(41):35553-61.
BCL9-2 protein, mouse  0   *Transcription Factors. Genes Dev. 2004 Sep 15;18(18):2225-30.
LIN-32 protein, C elegans  0   *Transcription Factors *Caenorhabditis elegans Proteins. Nature 1995 Jan 5;373(6509):74-8
MarR-family transcriptional regulatory protein, Mycobacterium  0   *Bacterial Proteins *DNA-Binding Proteins *Transcription Factors. Tuberculosis (Edinb). 2010 Jan;90(1):25-30
indeterminate(ID)-domain 14 protein, Arabidopsis  0   *Arabidopsis Proteins *Transcription Factors Alternative Splicing. Nat Commun. 2011;2() (dup#5):303
transcription factor AP4, mouse  0   *Transcription Factors. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14873-8
Vgll2a protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins. Dev Biol 2011 Sep 1;357(1):269-81
BTAF1 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *Transcription Factors. Mech Dev 2011 May-Jun;128(5-6):279-88
TORC1 protein complex, S cerevisiae  0   *Transcription Factors *Saccharomyces cerevisiae Proteins Autophagy. Autophagy. 2011 Aug 1;7(8):854-62
Barc protein, Drosophila  0   *Transcription Factors *Drosophila Proteins. Cell Stem Cell 2011 May 6;8(5):580-93
scratch2 protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins. Cell Death Differ. 2011 Jul;18(7):1196-207
SOG1 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2011 Jun 14;108(24):10004-9
NTM2 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Plant Physiol 2011 Jun;156(2):537-49
Snail2 protein, Xenopus  0   *Transcription Factors *Xenopus Proteins Zinc Fingers. Development 2011 Aug;138(15):3135-45
SMARCD3B protein, zebrafish  0   *Transcription Factors *Zebrafish Proteins. J Biol Chem 2008 Feb 8;283(6):3529-36
BAM8 protein, Arabidopsis  EC 3.2.1.2   *beta-Amylase *Transcription Factors *Arabidopsis Proteins DNA-Binding Proteins. Plant Cell 2011 Apr;23(4):1391-403
BAM7 protein, Arabidopsis  EC 3.2.1.2   *beta-Amylase *Transcription Factors *Arabidopsis Proteins DNA-Binding Proteins. Plant Cell 2011 Apr;23(4):1391-403
MYT1L protein, human  0   *Nerve Tissue Proteins *Transcription Factors. Nature. 2011 Aug 11;476(7359):228-31
Myt1l protein, mouse  0   *Nerve Tissue Proteins *Transcription Factors. Nature. 2011 Aug 11;476(7359):220-3
WRKY22 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Mol Cells 2011 Apr;31(4):303-13
TCP4 protein, Arabidopsis  0   *Transcription Factors *Arabidopsis Proteins. Biochem Biophys Res Commun 2011 Jul 1;410(2):276-81
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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