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Triazenes

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Definition: Compounds with three contiguous nitrogen atoms in linear format, H2N-N=NH, and hydrocarbyl derivatives.  do not confuse with TRIAZINES   
Examples Dacarbazine; Diminazene
Other names Compounds, Diazoamino; Diazoamino Compounds
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
O2-acetoxymethyl 1-(2-(4-(4-(4-methanesulfonylphenyl)-5H-furan-2-on-3-yl)phenylmethoxycarbonyl)pyrrolidin-1-yl)diazen-1-ium-1,2-diolate  0   *Triazenes 4-Butyrolactone/*analogs & derivatives. Bioorg Med Chem Lett 2011 Jul 1;21(13):3951-6
ZRF4 compound  0   *Pyrimidines *Triazenes. Leukemia 2011 Sep;25(9):1512-6
O2-vinyl 1-(2-(carboxylato)pyrrolidin-1-yl)diazen-1-ium-1,2-diolate  0   *Pyrrolidines *Triazenes Nitric Oxide Donors. Chem Biol Interact 2011 Aug 15;193(1):88-96
AL 237  0   *Dansyl Compounds *Triazenes. Mol Cancer Ther 2010 Apr;9(4):869-82
ZRBA1 compound  0   *Quinazolines *Triazenes. Biochem Pharmacol 2005 Aug 15;70(4):511-9
3-methyl-1,2,3-triazene  0   *Triazenes. Leuk Res 2005 Jun;29(6):605-6
6-(3-acetoxymethyl-3-methyltriazenyl)-4-(3'-bromophenylamino)quinazoline  0   *Quinazolines *Triazenes Receptor, Epidermal Growth Factor/antagonists & inhibitors. J Med Chem 2003 Dec 4;46(25):5546-51
BJ 2000  0   *Quinazolines *Triazenes. J Pharmacol Exp Ther 2002 Oct;303(1):238-46
(2-ethynylphenyl)triazene  0   *Triazenes. J Am Chem Soc 2002 Feb 27;124(8):1572-3
3-ethyl-3-(ethylaminoethyl)-1-hydroxy-2-oxo-1-triazene  0   *Triazenes. Metabolism 2001 Jun;50(6):703-7
1-(o-nitrophenyl)-3-(-thiazolyl)triazene  0   *Thiazoles *Triazenes Palladium. Spectrochim Acta A Mol Biomol Spectrosc 2000 Jun;56(A):1319-27
3-(3,3-dimethyl-1-triazenyl)-5-methyl-4,5-dihydroisoxazole  0   *Triazenes. Anticancer Res. 2000 May-Jun;20(3A):1513-8
1,3-diphenyl-1-triazene  136-35-6 1,3-diphenyltriazene  *Triazenes. Drug Metab Dispos 1999 Dec;27(12):1499-504
1-hydroxy-2-oxo-3-(3-aminopropyl)-3-isopropyl-1-triazene  0   *Triazenes. Br J Pharmacol 1998 Jun;124(4):804-10
2,4-diamino-5-(3-(3-(2-(acetyloxy)ethyl)-3-benzyltriazen-1-yl)-4-chlorophenyl)-6-ethylpyrimidine  0   *Pyrimidines *Triazenes Tetrahydrofolate Dehydrogenase/antagonists & inhibitors. J Med Chem 1997 Jun 6;40(12):1886-93
1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene  0   *Triazenes. FEBS Lett 1997 Mar 17;405(1):37-41
(1-hydroxy-2-oxo-3-(N-methyl-3-aminopropyl)-3-methyl-3-aminopropyl)-3-methyl-1-triazene  0   *Triazenes. Biochem Biophys Res Commun 1996 Aug 5;225(1):112-5
NOC 9  146724-86-9   *Triazenes. Biochem Biophys Res Commun 1996 Mar 18;220(2):306-9
1-(2-chloroethyl)-3-benzyl-3-(methylcarbamoyl)triazene  137668-39-4   *Triazenes. Biochem Pharmacol 1993 Jul 6;46(1):165-73
1-(4-carbamoylphenyl)-3,3-dimethyltriazene-1-oxide  142059-34-5   *Cyclic N-Oxides *Triazenes. Acta Crystallogr B 1992 Apr 1;48( Pt 2):213-7
4-(3,3-dimethyl-1-triazeno)phenylbutyric acid  138559-70-3   *Phenylbutyrates *Triazenes. Arzneimittelforschung 1991 Nov;41(11):1168-72
4-(3,3-dimethyl-1-triazeno)cinnamic acid  138559-71-4   *Cinnamates *Triazenes. Arzneimittelforschung 1991 Nov;41(11):1168-72
methyl 4-(3-ethyl-3-hydroxymethyltriazen-1-yl)benzoate  88392-04-5   *Benzoates *Triazenes. Anticancer Drug Des 1991;6(5):495
copper (II) 3-hydroxy-1-(4-phenylsulfonic acid)-3-phenyltriazene  129719-60-4   *Organometallic Compounds *Triazenes Copper. Analyst 1990;115(7):951
1-methyl-3-(2-nitrophenyl)triazene N-oxide  96603-22-4   *Cyclic N-Oxides *Triazenes. Pharm Acta Helv 1990;65(7):194
1-(4-carbethoxyphenyl)-3-hydroxymethyl-3-methyltriazene  70303-37-6   *Triazenes. Anticancer Drug Des 1988;3(2):91
1-4-(3-methyltriazeno)benzoic acid  40843-84-3   *Triazenes. Mutat Res 1987;189(3):349
1,3-di-(4(N-(4,6-dimethyl-2-pyrimidinyl))sulfamoylphenyl)triazene  110505-56-1   *Triazenes. Food Chem Toxicol 1987;25(5):373
1,3-diethyltriazene  63980-20-1   *Triazenes. Cancer Lett 1987;35(2):129
1-(4-nitrophenyl)-3,3-dimethyltriazene  7227-92-1   *Triazenes. Mutat Res 1987;190(3):183
1-(4-bromophenyl)-3,3-dimethyltriazene  7239-21-6   *Triazenes. Mutat Res 1987;190(3):183
4-(4-(3,3-dimethyl-1-triazene)-phenylsulfamide)-5,6-dimethoxypyrimidine  103947-07-5   *Triazenes. Yao Hsueh Hsueh Pao 1986;21(4):256
triacsin B  105201-47-6 2,4,6,8-Undecatetraenal, nitrosohydrazone, (?,E,E,E,E)  *Triazenes Coenzyme A Ligases/antagonists & inhibitors. J Antibiot (Tokyo) 1986;39(9):1211
triacsin A  105201-46-5 2,4-Undecadienal, nitrosohydrazone, (?,E,E)  *Triazenes Coenzyme A Ligases/antagonists & inhibitors. J Antibiot (Tokyo) 1986;39(9):1211
mannopyranosylmethyl-4-nitrophenyltriazene  101396-17-2   *Triazenes. J Biol Chem 1986;261(7):3457
1-(4-nitrophenyl)-3-methyltriazene  40643-39-8   *Triazenes. J Pharm Sci 1984;73(12):1691
titan yellow  1829-00-1   *Triazenes. Clin Chem 1985;31(3):462
1-(3-pyridyl)-3,3-diethyltriazene  21600-43-1   *Triazenes. Arch Gewulstforsch 1983;53(6):557
1-(3-phenyl)-3,3-diethyltriazene  13056-98-9   *Triazenes. Arch Geswulstforsch 1983;53(6):557
1,3-bis(2-cyano-5-(trifluoromethyl)phenyl)triazene  58458-08-5   *Triazenes. J Med Chem 1983;26(6):865
1-(4-carboxamidophenyl)-3,3-dimethyltriazene  33330-91-5 Benzamide, 4-(3,3-dimethyl-1-triazenyl)  *Triazenes. Biochem Pharmacol 1982;31(22):3629
1-(4-acetyphenyl)-3,3-dimethyltriazene  61947-73-7   *Triazenes. Biochem Pharmacol 1982;31(10):1887
triacsin D  76896-81-6 2,4,6-Undecatrienal, nitrosohydrazone, (2,E,E,E)  *Triazenes. J Antibiot (Tokyo) 1982;35(2):157
triacsin C  76896-80-5 2,4,7-Undecatrienal, nitrosohydrazone, (E,E,E)  *Triazenes.
Pharma Action Enzyme Inhibitors ; Vasodilator Agents
J Antibiot (Tokyo) 1982;35(2):157
1-(4-tolyl)-3,3-dimethyltriazene  7203-89-6   *Triazenes. Cancer Treat Rep 1982;66(1):115
1-(4-carboxyphenyl)-3,3-dimethyltriazene  7203-91-0   *Triazenes.
Pharma Action Antineoplastic Agents
Cancer Res 1981;41(6):2524
1-(4-tolyl)-3-acetyl-3-methyltriazene  66975-11-9 1-Triazene, 3-acetyl-3-methyl-1-(4-methylphenyl)  *Triazenes. J Pharm Sci 1980;69(12):1465
4-nitrophenyltriazene ouabain  0   *Triazenes Ouabain/*analogs & derivatives. J Biol Chem 1980;255(20):9936
1,3-di(4-sulfamoylphenyl)triazene  5433-44-3 Benzenesulfonamide, 4,4'-(1-triazene-1,3-diyl)bis  *Triazenes. JNCI 1980;65(3):547
beta-D-glucopyranosyl-4-nitrophenyltriazene  74957-61-2 D-glycero-D-gulo-Heptitol, 2,6-anhydro-1-deoxy-1-(3-(4-nitrophenyl)-1-triazenyl)  *Triazenes.
3-(3,3-dimethyl-1-triazeno)pyrazole-4-carboxamide  21466-00-2   *Triazenes. J Med Chem 22(11):1422;1979
1-(2,4,6-trichlorophenyl)-3-methyl-O-(triazenylmethyl)glucuronic acid  72040-50-7 beta-D-Glucopyranosiduronic acid, (1-methyl-3-(2,4,6-trichlorophenyl)-2-triazenyl)methyl  *Triazenes. Cancer Lett 7(4):209;1979
1-(4-nitrobenzyl)-3-(4-tolyl)triazene  17683-09-9   *Triazenes. J Agric Food Chem 27(4):746;1979
1-(2,4,6-trichlorophenyl)-3,3-dimethyltriazene  50355-74-3 3,3-dimethyl-1-(2,4,6-trichlorophenyl)-1- triazene  *Triazenes. Cancer Lett 1979;7(4):209; Mutat Res 61(2):401;1979
3-methyl-1-phenyltriazene  16033-21-9   *Triazenes. Chem Biol Interact 25(2-3):345;1979
methyl-4-tolyltriazene  21124-13-0   *Triazenes. Mutation Res 60(1):25;1979
beta-D-galactopyranosylmethyl-4-nitrophenyltriazene  59894-00-7 L-glycero-L-galacto-Heptitol, 2,6-anhydro-7-deoxy-7-(3-(4-nitrophenyl)-2-triazenyl)  *Triazenes. Biochem J 175(2):525;1978
4,4'-(diazoamino)dibenzenesulfonic acid  17596-06-4   *Triazenes. J Assoc Off Anal Chem 60(1):168;1977
1-(4-chlorophenyl)-3,3-dimethyltriazene  7203-90-9   *Triazenes. Cancer Lett 1(1):43;1977
1-(3-pyridyl-N-oxide)-3,3-dimethyltriazene  21600-42-0   *Triazenes. Mutat Res 21(3):123;1973
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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