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Triazoles

More information in Books or onNLM PubMed
Definition:   includes triazolines, triazolidines   
Examples Amitrole; Fluconazole; Guanazole; Itraconazole; Trapidil
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(2-(18F)fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo-isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole  0   *Indoles *Triazoles. J Neurochem. 2012 Apr;121(1):115-24
3-pyridin-4-yl-6-(thiophen-2-ylmethyl)-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazole  0   *Thiadiazoles *Triazoles. Chem Biol. 2011 Dec 23;18(12):1658-68.
6-(3,4-dimethoxyphenyl)-3-pyridin-2-yl-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazole  0   *Thiadiazoles *Triazoles. Chem Biol. 2011 Dec 23;18(12):1658-68.
6-cyclohexyl-3-furan-2-yl-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazole  0   *Thiadiazoles *Triazoles. Chem Biol. 2011 Dec 23;18(12):1658-68.
N-5-(2',4'-di-fluorophenyl)-2-furoyl-1H-1,2,4-triazole  0   *Triazoles. Chem Biol Drug Des. 2012 Jan;79(1):121-7
N-5-(4'-chlorophenyl)-2-furoyl-1H-1,2,4-triazole  0   *Triazoles. Chem Biol Drug Des. 2012 Jan;79(1):121-7
PF-184563  0   *Benzodiazepines *Triazoles Receptors, Vasopressin/antagonists & inhibitors. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5684-7.
1-(2-fluoroethyl)-4-(4-N,N-dimethylaminostyryl)-1H-1,2,3-triazole  0   *Aniline Compounds *Triazoles. J Med Chem. 2012 Jan 26;55(2):883-92.
MK0626  0   *Triazoles Dipeptidyl-Peptidase IV Inhibitors. Endocrinology. 2012 Feb;153(2); 564-73
N-(3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1H-pyrazol-5-yl)-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-4-methanamine  0   *Glucosides *Pyrazoles *Triazoles. J Agric Food Chem. 2011 Dec 14;59(23):12534-42
3-(2-nitrophenyl)-1H-1,2,4-triazole-5(4H)-thione  0   *Thiones *Triazoles Ligands. J Agric Food Chem. 2011 Oct 26;59(20):11352-8.
4-(4-(4-chlorophenyl)-5-(1,2,3)triazol-2-ylmethyl-4H-(1,2,4)triazol-3-yl)piperidin-1-yl-(3,5-difluorophenyl)methanone  0   *Triazoles *Piperidines Receptors, Vasopressin/antagonists & inhibitors. Eur J Pharmacol. 2011 Nov 30;670(2-3):347-55.
TASP0277308  0   *Sulfones *Triazoles. J Immunol. 2012 Jan 1;188(1):206-15
N-(1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-aminoacetamide  0   *Triazoles Glycine/*analogs & derivatives. Eur J Pharmacol. 2009 Jun 10;612(1-3):167-73.
3-((4-((1,2,4)triazolo(1,5-a)pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzonitrile  0   *Pyridines *Triazoles. Eur J Cancer. 2011 Nov;47(17):2642-53.
N3-(4-(4-morpholinocyclohexyl)phenyl)-1-(pyridin-2-yl)-1H-1,2,4-triazole-3,5-diamine  0   *Morpholines *Triazoles Proto-Oncogene Proteins c-kit/antagonists & inhibitors. J Med Chem. 2011 Oct 27;54(20):7184-92.
7-((2-(3-fluoropyridin-2-yl)-1H-imidazol-1-yl)methyl)-2-methyl-8-propyl-(1,2,4)triazolo(1,5-c)pyrimidine  0   *Pyrimidines *Triazoles Receptors, GABA-A GABA Agonists. Eur J Pharmacol. 2011 Oct 1;668(1-2):190-3.
2-(2-hydroxyphenyl)benzotriazole  0   *Triazoles. J Fluoresc. 2011 Jul;21(4):1721-8
5-iodo-1,2,3-triazole  0   *Triazoles. Org Lett. 2011 Aug 5;13(15):4060-3
2-(2-hydroxy-phenyl)-benzotriazole  0   *Triazoles. J Fluoresc. 2011 Jul;21(4):1721-8
2,2-dimethyl-3-(4-(naphthalen-2-ylamino)phenyl)-3-(1,2,4)triazol-1-yl-propionic acid methyl ester  0   *Triazoles 2-Naphthylamine/*analogs & derivatives. J Med Chem. 2011 Oct 13;54(19):6824-31.
3,4-diamino-1,2,4-triazole  0   *Diamines *Triazoles. J Phys Chem A. 2011 Aug 4;115(30):8550-62
anilino(1,2,4)triazolo(1,5-b)(1,2,4)thiadiazine 5,5-dione  0   *Thiadiazines *Triazoles. Med Chem. 2011 May 1;7(3):165-72
N-((3,5-difluoro-3'-(1H-1,2,4-triazol-3-yl)-4-biphenylyl)methyl)-2,3-dihydro-1H-inden-2-amine  0   *Indans *Triazoles Receptors, Opioid, mu. J Pharmacol Exp Ther. 2011 Oct;339(1):24-34.
(1,2,3)triazolo(3,4-g)quinoxaline  0   *Quinoxalines *Triazoles. Org Lett. 2011 Sep 2;13(17):4612-5
(1,2,5)chalcogenazolo(3,4-f)benzo(1,2,3)triazole  0   *Triazoles. Org Lett. 2011 Sep 2;13(17):4612-5
CEP 33779  0   *Pyridines *Triazoles Janus Kinase 2/antagonists & inhibitors. J Immunol 2011 Oct 1;187(7):3840-53
3-biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-1,2,4-triazole  0   *Biphenyl Compounds *Triazoles. J Med Chem 2011 Jan 13;54(1):387-91
2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol-2-hydroxybenzoic acid  0   *Triazoles *Benzoic Acids. Acta Crystallogr C. 2011 Sep;67(Pt 9):o370-2
HX4 compound  0   *Imidazoles *Triazoles Radiopharmaceuticals. Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14620-5
SEN1176  0   *Pyrroles *Pyrimidines *Triazoles Anti-Inflammatory Agents. Alzheimers Dis. 2011;25(2):219-29
tris(triazolyl)borate  0   *Borates *Triazoles. Dalton Trans. 2011 Aug 7;40(29):7517-33
3-methoxy-1,5-bis(4-methoxyphenyl)-1H-1,2,4-triazole  0   *Triazoles Cyclooxygenase Inhibitors Cyclooxygenase 1. Biochem Pharmacol 2011 Oct 1;82(7):746-54
(+)-JQ1 compound  0   *Azepines *Triazoles. Angew Chem Int Ed Engl. 2011 Jun 20;50(26):5801-3
N-(3,5-dimethylphenyl)-2-((5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl)sulfanyl)acetamide  0   *Acetamides *Triazoles Choline Kinase/antagonists & inhibitors. Oncogene 2011 Jul 28;30(30):3370-80
5-(1H-tetrazol-1-yl)-1,2,4-triazole  0   *Tetrazoles *Triazoles. J Phys Chem A. 2011 Jun 9;115(22):5693-707
3-amino-6-(4-chlorophenyl)-8-phenyl-1H-pyrido(2,3-d)(1,2,4)triazolo(4,3-a)pyrimidin-5-one  0   *Pyrimidinones *Triazoles. Eur J Med Chem 2011 Jun;46(6):2031-6
targocil  0   *Quinazolines *Triazoles. Bioorg Med Chem Lett 2010 Mar 1;20(5):1767-70
4-(((2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)methylamino)methyl)-N-(phenyl)benzenesulfonamide  0   *Sulfonamides *Triazoles. ChemMedChem. 2011 May 2;6(5):816-25
penipanoid A  0   *Carboxylic Acids *Triazoles. J Nat Prod. 2011 May 27;74(5):1331-4
3-(1H-benzo(d)(1,2,3)triazol-1-yl)-1-oxo-1-m-tolylpropan-2-yl-nicotinate  0   *Triazoles Niacin/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Jun;79(1):219-25
8-(1-pentyl-1H-1,2,3-triazole-4-yl)-2'-deoxyadenosine  0   *Deoxyadenosines *Triazoles. Nucleic Acids Res 2011 May;39(10):4513-24
phenylaza-18-crown-6-triazol  0   *Aza Compounds *Triazoles. Chem Commun (Camb). 2011 Apr 28;47(16):4685-7
1,1'-methylenebis(1,2,4-triazole)  0   *Triazoles. Dalton Trans. 2011 Apr 28;40(16):4095-103
2-(4-(3-quinolin-6-ylmethyl-3H-(1,2,3)triazolo(4,5-b)pyrazin-5-yl)pyrazol-1-yl)ethanol  0   *Pyrazines *Triazoles. Drug Metab Dispos 2011 Mar;39(3):383-93
2-amino-3-(1-(2-fluoroethyl)-1H-(1,2,3)triazol-4-yl)propanoic acid  0   *Triazoles Alanine/*analogs & derivatives Fluorine Radioisotopes. Mol Imaging 2010 Dec;9(6):329-42
3-methyl-4-phenyl-5-(2-pyridyl)-1,2,4-triazole  0   *Pyridines *Triazoles. Phys Chem Chem Phys. 2011 Feb 21;13(7):2945-52
2-(4-(4-methylbenzyl)-(1,4)diazepan-1-yl)-N-(4,5-dihydro-1-methyl-(1,2,4)triazolo(4,3-a)quinolin-7-yl)acetamide  0   *Azepines *Triazoles. Chem Biol Drug Des 2011 Jan;77(1):98-103
3-(4-(3-methylbut-2-enyloxy)styryl)-(1,2,4)triazolo(3,4-a)phthalazine  0   *Phthalazines *Triazoles. J Med Chem 2011 Mar 10;54(5):1449-61
4H-pyrazolo(4,5-f)(1,2,4)triazolo(4,3-b)(1,2,4)triazepine  0   *Azepines *Triazoles. Eur J Med Chem. 2011 Feb;46(2):631-5
(1,2,4)triazolo(3,4-a)thienotetrahydroisoquinoline  0   *Isoquinolines *Triazoles. Eur J Med Chem. 2011 Feb;46(2):567-78
4-(amino)-5-phenyl-4H-1,2,4-triazole-3-thiol  0   *Triazoles. Pak J Pharm Sci. 2011 Apr;24(2):109-12
abscinazole E1  0   *Triazoles. Bioorg Med Chem 2011 Jan 1;19(1):406-13
6-(1-(2-fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl)quinoline  0   *Quinolines *Triazoles Fluorine Radioisotopes. Bioorg Med Chem 2011 Jan 1;19(1):102-10
MK-5435  0   *Indoles *Triazoles Excitatory Amino Acid Agents. Synapse. 2011 Feb;65(2):125-35
MK-1312  0   *Indoles *Triazoles Excitatory Amino Acid Agents. Synapse. 2011 Feb;65(2):125-35
2-dodecyl-4,7-di(thiophen-2-yl)-2H-benzo(d)(1,2,3)triazole  0   *Thiophenes *Triazoles. Macromol Biosci. 2010 Dec 8;10(12):1557-65
MK-5286  0   *Hydrocarbons, Fluorinated *Thiophenes *Triazoles. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7440-3
Stratego  0   *Acetates *Triazoles Drug Combinations. Environ Toxicol Chem 2010 Nov;29(11):2477-80
diarylmethyl(1H-1,2,4-triazol-1-ylmethyl)silane  0   *Silanes *Triazoles. Chemistry. 2010 Dec 3;16(45):13519-27
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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