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Triiodothyronine

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Definition: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.     
See Also Receptors, Thyroid Hormone
Other names T3 Thyroid Hormone; Liothyronine; Thyroid Hormone, T3; CytomelDrugs* : LIOTHYRONINE SODIUM; TRIOSTAT; CYTOMEL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
triiodothyropropionine  0   Triiodothyronine/*analogs & derivatives.
3,3',5-triiodothyroacetic acid sulfate  95786-11-1   Triiodothyronine/*analogs & derivatives. Endocrinology 1989;125(1):424
triiodothyronine glucuronide  29919-72-0   *Glucuronates Triiodothyronine/*analogs & derivatives. Endocr Res 1987;13(3):215
thyroid hormone-binding proteins  0   *Carrier Proteins *Membrane Proteins *Thyroid Hormones Aldehyde Dehydrogenase Neoplasm Proteins Triiodothyronine Xenopus Proteins. J Histochem Cytochem 1987;35(10):1043
Plethoryl  100216-56-6 Retinol, 2-amino-1,6,6a,7,8,9a-hexahydro-7-hydroxy-8-(hydroxymethyl)-, (6aS-(6aalpha,7alpha,8beta,9aalpha))  *Cyclohexanones Drug Combinations Triiodothyronine/*analogs & derivatives Vitamin A/*analogs & derivatives. Gastroenterol Clin Biol 1984;8(10):770
carbamylated triiodothyronine  99780-73-1 L-Tyrosine, 3,5-diiodo-O-(3-iodo-4-(((phenylamino)carbonyl)oxy)phenyl)-, (1R-(1alpha(Z),2beta(1E,3S*),5alpha))  Triiodothyronine/*analogs & derivatives. Rinsho Byori 1984;32(8):895
3,3',5-triiodothyronamine  4731-88-8   Triiodothyronine/*analogs & derivatives. Horm Metab Res 1983;15(12):602
triiodothyronine sulfate  31135-55-4 L-Tyrosine, 3,5-diiodo-O-(3-iodo-4-(sulfooxy)phenyl)  Triiodothyronine/*analogs & derivatives. Endocrinology 1983;112(4):1547
N-bromoacetyl-3,3',5-triiodothyronine  76970-94-0   Triiodothyronine/*analogs & derivatives Iodine Radioisotopes. Proc Natl Acad Sci USA 1982;79(18):5527
N-2-diazo-3,3,3-trifluoropropionyl-3,5,3'-triiodothyronine  83093-58-7 L-Tyrosine, N-(2-diazo-3,3,3-trifluoro-1-oxopropyl)-O-(4-hydroxy-3-iodophenyl)-3,5-diiodo  *Diazonium Compounds Triiodothyronine/*analogs & derivatives.
glycosylated triiodothyronine  0   Triiodothyronine/*analogs & derivatives Glycosylation. Endocrinol Jpn 1981;28(3):277
3'-bromo-3,5,5'-triiodothyronine  77667-01-7 L-Tyrosine, O-(3-bromo-4-hydroxy-5-iodophenyl)-3,5-diiodo  Triiodothyronine/*analogs & derivatives. J Clin Chem Clin Biochem 1981;19(4):191
3'-isopropyl-3,5,5'-triiodothyronine  62901-32-0   Triiodothyronine/*analogs & derivatives. J Clin Chem Clin Biochem 1981;19(4):191
thyroxine, triiodothyronine drug combination  8061-58-3 O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine mixt. with O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine  *Thyroxine *Triiodothyronine Drug Combinations. Med Lett Drug Ther 12(18):73;1970; Pol Tyg Lek 1979;34(47):1841; Pol Tyg Lek 31(52):2233;1976; Sem Hop 54(41-42):1291;1978
3,3',5-triiodothyropropionic acid  51-26-3 4-(4-hydroxy-3-iodophenoxy)-3,5- diiodobenzenepropanoic acid  Triiodothyronine/*analogs & derivatives. Exp Hematol 1979;7(9):490; Experientia 31(10):1218;1975; J Clin Endocrinol 46(1):91;1978
3,3',5-triiodothyroacetic acid  51-24-1 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid  Triiodothyronine/*analogs & derivatives. Acta Endocrinol (Copenh):92(3):455; Ann Endocrinol 35(6):669;1974; Endocrinology 1980;106(4):1133; Endocrinology 98(3):666;1976; Exp Hematol 1979;7(9):490; Experientia 31(10):1218;1975; J Clin Endocrinol Metab 1980;50(2):223; J Clin Endocrinol Metab 46(1):91;1978; J Clin Invest 63(6):1229;1979; J Endocrinol 65:341;1975; Life Sci 22:15;1978; Sem Hop Ther 51(1):11;1975; Sem Hop Ther 52(2):99;1976
3,3',5-triiodothyroacetic acid N,N-diethanolamine (1:1) complex  1052-92-2 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid, compd. with 2,2'-iminobis(ethanol) (1:1)  Triiodothyronine/*analogs & derivatives. Biochem Biophys Res Commun 52(2):430;1973; Lancet 2(8031):221;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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