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Trimethaphan

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Definition: A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery.     
Pharmacological Action Adjuvants, Anesthesia; Antihypertensive Agents; Ganglionic Blockers; Nicotinic Antagonists 		Other names Trimetaphan; Thimethaphan
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
trimetaphan nitroprusside  115722-30-0   *Nitroprusside *Trimethaphan Drug Combinations. Br J Anaesth 1988;60(7):797
trimethaphan camsylate  68-91-7 decahydro-2-oxo-1,3-bis(phenylmethyl)thieno(1',2':1,2) thieno(3,4-d)imidazol-5-ium, salt with (1S)-7,7-dimethyl-2-oxobicyclo(2.2.1)heptane-1-methanesulfon ic acid (1:1)  *Trimethaphan.
Pharma Action Vasodilator Agents 		Anesthesiol Reanim (3):49;1978; Kardiologiia 19(6):55;1979ARFONAD

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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