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Trimethylsilyl Compounds

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Definition: Organic silicon derivatives used to characterize hydroxysteroids, nucleosides, and related compounds. Trimethylsilyl esters of amino acids are used in peptide synthesis.  DF: TRIMETHYLSILYL CPDS    Other names Compounds, Trimethylsilyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bis(trimethylsilyl)cyclopentenone  0   *Trimethylsilyl Compounds. Chemistry. 2011 Jun 27;17(27):7399-403
1-methoxy-3-trimethylsilyloxy-1,3-butadiene  0   *Butadienes *Trimethylsilyl Compounds. Chemistry. 2011 Jun 27;17(27):7592-604
poly(4,6-bis(phenoxy)-2-diphenylamino-s-triazine)co(2,5-bis(trimethylsily)-1,4-phenylenevinylene)  0   *Polyvinyls *Trimethylsilyl Compounds. J Nanosci Nanotechnol. 2011 May;11(5);4439-43
1,2-bis(trimethylsilyloxy)cyclobutene  0   *Cyclobutanes *Trimethylsilyl Compounds. Org Lett. 2011 Feb 4;13(3):526-9
3-tri-n-butylstannyl-1-trimethylsilyl-1-propyne  0   *Alkynes *Trimethylsilyl Compounds. Chem Commun (Camb). 2010 Jun 28;46(24):4297-9
4-deacetyl-1-dimethylsilyl-7-triethylsilylbaccatin III  0   *Alkaloids *Trimethylsilyl Compounds *Taxoids. J Org Chem. 2009 Mar 6;74(5):2186-8
trimethylsilyl triflate-2,2'-bipyridyl  0   *Trimethylsilyl Compounds 2,2'-Dipyridyl/*analogs & derivatives. Chem Pharm Bull (Tokyo). 2010;58(3):426-8
bis(3,6-bis(trimethylsilyl)benzene-1,2-dithiolato)  0   *Trimethylsilyl Compounds. Inorg Chem. 2009 Dec 7;48(23):10913-25
1-methoxy-1,3-bis(trimethylsilyloxy)-1,3-butadiene  0   *Butadienes *Trimethylsilyl Compounds. Org Biomol Chem 2009 May 7;7(9):1931-8
2-(trimethylsilyl)benzoic acid  0   *Trimethylsilyl Compounds *Benzoic Acids. Nucleic Acids Symp Ser (Oxf) 2008;(52):301-2
tris(trimethylsilyl)methyllithium  0   *Organometallic Compounds *Trimethylsilyl Compounds Lithium. J Org Chem 2009 Jan 16;74(2):719-29
p-tolyl 2-trimethylsilyl-1-azulenyl sulfone  0   *Trimethylsilyl Compounds *Azulenes. J Org Chem. 2008 Oct 17;73(20):7971-7
o-trimethylsilylbenzaldehyde  0   *Benzaldehydes *Trimethylsilyl Compounds. Angew Chem Int Ed Engl 2008;47(37):7082-6
calcium bis(trimethylsilyl)amide  0   *Trimethylsilyl Compounds Calcium. Dalton Trans 2008 Mar 14;(10):1292-4
2-fluoro-6-O-(trimethylsilylethyl)-2'-deoxyinosine  0   *Trimethylsilyl Compounds Inosine/*analogs & derivatives. Curr Protoc Nucleic Acid Chem. 2001 May;Chapter 1():Unit 1.3
2-(3-(trimethoxysilyl)propyldisulfanyl)propionic acid  0   *Trimethylsilyl Compounds. Chem Commun (Camb) 2007 Oct 7;(37):3850-2
1,2-bis(trimethylsilyl)benzene  0   *Trimethylsilyl Compounds. J Org Chem 2007 Dec 7;72(25):9750-2
cinnamyltrimethylsilane  0   *Cinnamates *Trimethylsilyl Compounds. Bioorg Med Chem. 2007 Dec 15;15(24):7599-617
bis(trimethylsilyl)chromate  0   *Organometallic Compounds *Trimethylsilyl Compounds. Molecules 2007;12(5):958-64
2-trimethylsilylethyl-N-n-butylcarbamate  0   *Carbamates *Trimethylsilyl Compounds Butyrylcholinesterase. J Biochem Mol Toxicol 2007;21(1):24-31
tris(trimethylsilyl)silyl enol ether  0   *Trimethylsilyl Compounds. Nat Protoc 2006;1(5):2434-8
(trifluoromethyl)-trimethylsilane  0   *Hydrocarbons, Fluorinated *Trimethylsilyl Compounds. J Phys Chem A 2005 Sep 22;109(37):8438-42
3-(trimethylsilyl)propionic acid  0   *Propionic Acids *Trimethylsilyl Compounds. J Org Chem 2007 Aug 31;72(18):6956-60
3,9-diethyl-3,9-bis(trimethylsilylpropyloxymethyl)-1,5,7,11-tetraoxaspiro(5.5)undecane  0   *Spiro Compounds *Trimethylsilyl Compounds. Dent Mater 2007 Aug;23(8):1011-7
1,1-difluoro-1-trimethylsilanyl methylphosphonic acid  0   *Trimethylsilyl Compounds. J Am Chem Soc 2006 Sep 27;128(38):12360-1
trimethylsilyl fluorosulfonyldifluoroacetate  0   *Trimethylsilyl Compounds. Org Lett 2006 Nov 23;8(24):5549-51
2,5-bis(trimethylsilyloxy)furan  0   *Furans *Trimethylsilyl Compounds. J Org Chem 2007 Jun 22;72(13):5016-9
3,3-bis(trimethylsilyl)-2-methyl-1-propene  0   *Allyl Compounds *Trimethylsilyl Compounds. Org Lett 2006 Sep 28;8(20):4393-6
trichloromethyltrimethylsilane  0   *Trimethylsilyl Compounds. J Org Chem 2007 May 11;72(10):3925-8
bis(trimethoxysilyl)ethane  0   *Trimethylsilyl Compounds Ethane/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2006 Nov;65(3-4):779-86
trimetoxypropylsilane  0   *Trimethylsilyl Compounds. Spectrochim Acta A Mol Biomol Spectrosc. 2006 Nov;65(3-4):779-86
2-debenzoyl-2-m-methoxybenozyl-7-triethylsilyl-13-oxo-14-hydroxybaccatin III 1,14-carbonate  0   *Trimethylsilyl Compounds *Taxoids. Bioorg Med Chem Lett 2006 Oct 15;16(20):5389-91
poly(4-trimethylsilylstyrene)  0   *Polystyrenes *Trimethylsilyl Compounds. Biomacromolecules 2006 Jun;7(6):1696-9
Brassard's diene  0   *Alkenes *Trimethylsilyl Compounds. Chemistry. 2004 Nov 19;10(23):5946-70
2,2'-bis(trimethylsilyl)-6,6'-bis(dimethylthexylsilyl)diphenylacetylene  0   *Biphenyl Compounds *Trimethylsilyl Compounds. Chem Commun (Camb). 2005 May 28;(20):2606-8
2,3,9,10-tetrakis(trimethylsilyl)pentacene  0   *Polycyclic Compounds *Trimethylsilyl Compounds. Chem Commun (Camb) 2005 Jan 7;(1):66-8
1-(1H-1,2,4-triazol-1-yl)-2-(4-fluorophenyl)-3-trimethylsilylpropan-2-ol  0   *Trimethylsilyl Compounds *Propanols. Bioorg Med Chem. 2004 Jul 1;12(13):3561-7
2-(4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-trimethylsilylpropan-2-ol  0   *Triazoles *Trimethylsilyl Compounds. Pest Manag Sci 2004 Sep;60(9):875-80
alpha-trimethylsilanylacetate  0   *Trimethylsilyl Compounds. Chem Pharm Bull (Tokyo). 2004 Jan;52(1):125-9
1-triazolyl-5-trimethylsilyl-2-pentanol  0   *Triazoles *Trimethylsilyl Compounds. Chem Pharm Bull (Tokyo). 2003 Sep;51(9):1113-6
1-triazolyl-4-trimethylsilyl-2-butanol  0   *Triazoles *Trimethylsilyl Compounds. Chem Pharm Bull (Tokyo). 2003 Sep;51(9):1113-6
potassium trimethylsilanolate  0   *Trimethylsilyl Compounds Potassium. J Org Chem. 2003 Nov 14;68(23):9151-4
trimethylsilyl hydroxypropylcellulose  0   *Trimethylsilyl Compounds Cellulose/*analogs & derivatives. Carbohydr Res. 2003 Mar 14;338(6):535-40
2-trimethylsilyl-2-hydroxyethylcyanide  0   *Nitriles *Trimethylsilyl Compounds. Biotechnol Lett 2003 Feb;25(3):219-22
acetyltrimethylsilane  0   *Trimethylsilyl Compounds. Biotechnol Lett 2003 Feb;25(3):219-22
Zilpaterol  0   *Trimethylsilyl Compounds. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jan 5;783(1):141-9
(2-Phenyl-2-trimethylsilyl)ethyl  0   *Trimethylsilyl Compounds. Angew Chem Int Ed Engl 2002 Jan 18;41(2):317-21
(trimethylsilyl)diazaomethane  0   *Trimethylsilyl Compounds Diazomethane/*analogs & derivatives. Org Lett 2002 Feb 21;4(4):489-92
4-trimethylsilyl-3-butyn-2-ol  0   *Butanols *Trimethylsilyl Compounds. Org Lett 2001 Oct 18;3(21):3369-72
allyltrimethylsilane  762-72-1   *Trimethylsilyl Compounds. Carbohydr Res 2001 May 18;333(2):221-4
lithium bis(trimethylsilyl)amide  0   *Trimethylsilyl Compounds Lithium. Org Lett 2001 Aug 23;3(17):2729-32
2-(thiomethyl)-3-trimethylsilyl-1-propenyl  0   *Trimethylsilyl Compounds. J Org Chem 2001 Jul 27;66(15):5237-40
poly(trimethoxysilylpropyl methacrylate)  0   *Methacrylates *Trimethylsilyl Compounds. Biomaterials 2001 Jan;22(2):99-111
trimethylsilyl iodide  0   *Trimethylsilyl Compounds Indicators and Reagents. Bioorg Med Chem Lett 2000 Oct 16;10(20):2311-3
2-(trimethylsilyl)ethanethiol  18143-30-1   *Sulfhydryl Compounds *Trimethylsilyl Compounds. J Org Chem 2000 Jan 14;65(1):249-53
dipropyl(4-trimethylsilylethynylcyclohex-3-enyl)amine  0   *Cyclohexylamines *Trimethylsilyl Compounds. J Med Chem 2000 Feb 24;43(4):756-62
TAC 101  0   *Benzoates *Trimethylsilyl Compounds. Biol Pharm Bull 1996 Oct;19(10):1322-8
4-nitro-1-(trimethylsilylethynyl)benzene  0   *Nitrobenzenes *Trimethylsilyl Compounds. Acta Crystallogr C 1998 Apr 15;54(Pt 4):489-91
N,O-bis(trimethylsilyl)trifluoroacetamide  0   *Acetamides *Trimethylsilyl Compounds. J Anal Toxicol 1996 Oct;20(6):416-24
N-methyl-N-trimethylsilylheptafluorobutyramide  0   *Amides *Trimethylsilyl Compounds. J Anal Toxicol 1996 Oct;20(6):345-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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