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Trioxsalen

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Definition: Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.     
Pharmacological Action Photosensitizing Agents 		Other names Trioxysalen; Trimethylpsoralen; NSC71047; NSC 71047; Trisoralen; Trioxisalenum; ICN Brand of Trioxsalen; 4,5',8-Trimethylpsoralen; 2,5,9-Trimethyl-7H-furo(3,2-g)benzopyran-7-one; NSC-71047Drugs* : TRISORALEN
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
iodomercurio-4',5'-dihydrotrimethylpsoralen  0   *Organomercury Compounds Trioxsalen/*analogs & derivatives. Biochem Pharmacol 2005 Dec 5;70(12):1726-34
psoAG10 compound  0   *Oligonucleotides Trioxsalen/*analogs & derivatives. J Biol Chem 1995 Sep 22;270(38):22595-601
1,15-bis(4'-trioxsalen)-2,6,10,14-tetramethyl-2,6,10,14-tetrazapentadecane  84067-18-5 7H-Furo(3,2-g)(1)benzopyran-7-one, 4,4'-(2,6,10,14-tetramethyl-2,6,10,14-tetraazapentadecane-1,15-diyl)bis(2,5,9-trimethyl)  Trioxsalen/*analogs & derivatives. J Mol Biol 1982;159(1)
2-pyridyldithioethylmethylamidodiethoxyethane methylaminomethyltrimethylpsoralen  83353-04-2 Propanamide, N-methyl-N-(2-(2-(2-(methyl((2,5,9-trimethyl-7-oxo-7H-furo(3,2-g)(1)benzopyran-3-yl)methyl)amino)ethoxy)ethoxy)ethyl)-3-(2-pyridinyldithio)  Trioxsalen/*analogs & derivatives. Proc Natl Acad Sci USA 1982;79(15):4594
4,8-dimethyl-5'-carboxypsoralen  15912-90-0 5,9-dimethyl-7-oxo-7H-furo(3,2-g)(1)benzopyran-2-carboxylic acid  Trioxsalen/*analogs & derivatives. Farmaco(Sci) 34(3):234;1979
aminomethyltrioxsalen  64358-50-5 7H-furo(3,2-g)(1)benzopyran-7-one, 3-(aminomethyl)-2,5,9-trimethyl  Trioxsalen/*analogs & derivatives Tritium.
Pharma Action Cross-Linking Reagents ; Photosensitizing Agents ; Anti-HIV Agents 		Biochemistry 1979;18(13):2905; Biochim Biophys Acta 563(2):343;1979; Eur J Biochem 95(1):203;1979; Nucleic Acids Res 1979;7(3):689; Proc Natl Acad Sci USA 76(2):755;1979
hydroxymethyltrioxsalen  62442-59-5 3-(hydroxymethyl)-2,5,9-trimethyl-7H-furo(3,2-g)(1)benzopyran-7-one  Trioxsalen/*analogs & derivatives.
Pharma Action Cross-Linking Reagents 		Proc Natl Acad Sci USA 75(4):1642;1978

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