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Tryptamines

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Definition: Decarboxylated monoamine derivatives of TRYPTOPHAN.     
See Also Receptors, Serotonin
Examples N,N-Dimethyltryptamine; Serotonin 		Other names Indolylethylamines; Triptans
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-bromo-N-methyltryptamine  0   *Tryptamines Alkaloids. J Nat Prod. 2011 Oct 28;74(10):2304-8
JNJ 26854165  881202-45-5   *Tryptamines.
Pharma Action Radiation-Sensitizing Agents 		Cancer Lett. 2011 Dec 22;312(2):209-18
1-hydroxy-N-methoxycarbonyltryptamine  0   *Tryptamines Osteoblasts/drug effects. J Pharmacol Sci. 2011;115(2):214-20
SST-VEDI-1 compound  0   *Tryptamines. J Biochem 2009 Feb;145(2):239-47
5-chlorotryptamine  0   *Tryptamines. Ontogenez 1988 Sep-Oct;19(5):499-507
N(1)-(6-chloroimidazo(2,1-b)(1,3)thiazole-5-sulfonyl)tryptamine  0   *Thiazoles *Tryptamines Receptors, Serotonin. J Med Chem 2007 Nov 15;50(23):5535-8
bacillamide C  0   *Thiazoles *Tryptamines. J Nat Prod 2007 Nov;70(11):1793-6
bacillamide B  0   *Thiazoles *Tryptamines. J Nat Prod 2007 Nov;70(11):1793-6
N-caffeoyltryptamine  0   *Caffeic Acids *Tryptamines. J Chromatogr B Analyt Technol Biomed Life Sci 2007 Jun 1;852(1-2):398-402
alpha-methyltryptamine sulfonamide  0   *Sulfonamides *Tryptamines. Bioorg Med Chem Lett. 2007 Jan 15;17(2):315-9
5-methoxy-N-methyl,N-isopropyl tryptamine  0   *Tryptamines. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Jan 30;31(1):288-91
N, N, N-trimethyl-4-phosphoryloxytryptamine  0   *Organophosphorus Compounds *Tryptamines. Planta Med. 2006 Jun;72(7):665-6
5-methoxy-2-phenyl-N,N-dimethyltryptamine  0   *Tryptamines. Neuropharmacology 2006 Mar;50(4):412-20
granulatamide B  0   *Tryptamines. J Nat Prod 2006 Apr;69(4):668-70
granulatamide A  0   *Tryptamines. J Nat Prod 2006 Apr;69(4):668-70
N-bromoacetyltryptamine  0   *Tryptamines. Neuro Endocrinol Lett 2005 Oct;26(5):581-92
ZTR-5 compound  0   *Tryptamines *Oxazolidinones. J Pharm Biomed Anal 2005 Sep 15;39(3-4):796-800
5-carboxytryptamine  0   *Tryptamines. J Neurosci 2004 Dec 1;24(48):10950-62
BrMT neurotoxin, Calliostoma canaliculatum  0   *Tryptamines Neurotoxins. J Nat Prod 2005 Feb;68(2);162-7
N-acetyl-5-ethoxytryptamine  0   *Tryptamines. Bioorg Chem 2004 Feb;32(1):1-12
N-salicyloyltryptamine  0   *Salicylates *Tryptamines. Br J Pharmacol 2003 Dec;140(7):1331-9
N-desmethyl eletriptan  0   *Pyrrolidines *Tryptamines. Drug Metab Dispos. 2003 Jul;31(7):861-9
bis(6-bromo-2-mercaptotryptamin-2-yl)disulfide  0   *Disulfides *Tryptamines. J Biol Chem 2003 Sep 12;278(37):34934-42
haploscleridamine  0   *Alkaloids *Tryptamines. J Nat Prod 2002 Apr;65(4):628-9
roehybridine-N-oxide  0   *Aporphines *Tryptamines. Fitoterapia 2001 Dec;72(8):875-87
N(b)-benzyl-2,3-dihydro-2-oxotryptamine  0   *Tryptamines. J Nat Prod 2001 Aug;64(8):1032-9
2,3-dihydro-2-oxotryptamine  0   *Tryptamines. J Nat Prod 2001 Aug;64(8):1032-9
2-(3,5-dimethylphenyl)tryptamine  0   *Tryptamines. Bioorg Med Chem Lett 2001 Apr 23;11(8):1073-6
4-fluoro-5-methoxy-N,N-dimethyltryptamine  0   *Tryptamines. J Med Chem 2000 Nov 30;43(24):4701-10
N1-benzenesulfonyl-5-methoxy-N,N-dimethyltryptamine  0   *Tryptamines. Bioorg Med Chem Lett 2000 Oct 16;10(20):2295-9
5-methoxycarbonylamino-N-acetyltryptamine  0   *Tryptamines. Neuropharmacology 2000 Jul 24;39(10):1865-71
almotriptan  154323-57-6   *Tryptamines Migraine Disorders.
Pharma Action Serotonin Receptor Agonists 		Clin Pharmacol ther 2000 May;67(5):498-503ALMOTRIPTAN MALATE; AXERT
N-pentanoyl-2-benzyltryptamine  0   *Tryptamines Melatonin/antagonists & inhibitors. Cell Tissue Res 2000 Mar;299(3):299-306
F 11356  170911-68-9   *Nitriles *Piperazines *Tryptamines. J Pharmacol Exp Ther 1999 Jul;290(1):83-95
N-methyl-5-tert-butyltryptamine  0   *Tryptamines Receptors, Serotonin/agonists. J Med Chem 1999 Feb 11;42(3):526-31
eletriptan  0   *Pyrrolidines *Tryptamines.
Pharma Action Serotonin Receptor Agonists 		Naunyn Schmiedebergs Arch Pharmacol 1998 Aug;358(2):212-9RELPAX
frovatriptan  0   *Carbazoles *Tryptamines Migraine Disorders.
Pharma Action Serotonin Receptor Agonists 		J Cardiovasc Pharmacol 1997 Jul;30(1):136-41FROVA
naratriptan  121679-13-8   *Piperidines *Tryptamines.
Pharma Action Vasoconstrictor Agents ; Serotonin 5-HT1 Receptor Agonists 		Cephalalgia 1997 May;17(3):145-52NARATRIPTAN; AMERGE
2-iodo-5-methoxycarbonylamino-N-acetyltryptamine  0   *Tryptamines Iodine Radioisotopes Ligands. Eur J Pharmacol 1996 Apr 22;301(1-3):159-68
BMS 180048  171171-42-9   *Sulfonamides *Tryptamines. J Chromatogr B Biomed Appl 1994 Apr 12;678(2):269-77
rizatriptan  145202-66-0   *Triazoles *Tryptamines Migraine Disorders.
Pharma Action Serotonin Receptor Agonists 		J Med Chem 1995 May 12;38(10):1799-810MAXALT; MAXALT-MLT; RIZATRIPTAN BENZOATE
LY 293284  141318-62-9 Ethanone, 1-(4-(dipropylamino)-1,3,4,5-tetrahydrobenz(cd)indol-6-yl)-, (R)  *Tryptamines. J Pharmacol Exp Ther 1994 Sep;270(3):1270-81
zolmitriptan  139264-17-8   *Tryptamines *Oxazolidinones.
Pharma Action Serotonin 5-HT1 Receptor Agonists 		Headache 1994 Jul-Aug;34(7):394-9ZOMIG; ZOMIG-ZMT; ZOLMITRIPTAN
5-(nonyloxy)tryptamine  157798-12-4   *Tryptamines. J Med Chem 1994 Sep 2;37(18):2828-30
L 694247  137403-12-4 Methanesulfonamide, N-(4-((5-(3-(2-aminoethyl)-1H-indol-5-yl)-1,2,4-oxadiazol-3-yl)methyl)phenyl)  *Oxadiazoles *Tryptamines. Br J Pharmacol 1993 Nov;110(3):1196-2000
N-butanoyl-5-methyltryptamine  153342-22-4   *Tryptamines. J Pineal Res 1993 Sep;15(2):104-7
7-S-glutathionyltryptamine-4,5-dione  130369-71-0   *Tryptamines Glutathione/*analogs & derivatives. Biochem Pharmacol 1993 Nov 2;46(9):1637-52
11-N-(3-nitrobenzenesulfonyl)undecanoyl tryptamine  150214-87-2   *Nitrobenzenes *Tryptamines. Biophys Chem 1993 May;46(3):273-81
11-N-(3-acetylbenzenesulfonyl)undecanoyl tryptamine  150214-86-1   *Benzenesulfonates *Tryptamines. Biophys Chem 1993 May;46(3):273-81
myristoyl tryptamine  21469-16-9   *Myristic Acids *Tryptamines. Biophys Chem 1993 May;46(3):273-81
5,5'-dihydroxy-4,4'-bitryptamine  108535-01-9   *Tryptamines. J Neurochem 1992 Oct;59(4):1392-8
2-(N-(2-propynyl)aminomethyl)-1-methyl-5-methoxyindole  130445-58-8   *Alkynes *Tryptamines. Biochem Soc Trans 1991;19(1):215
2-(N-(2-propynyl)-aminomethyl)-1-methyl-5-hydroxyindole  133681-83-1   *Alkynes *Tryptamines. Biochem Soc Trans 1991;19(1):215
2-(N-(2-propynyl)aminomethyl)-1-methylindole  122368-24-5   *Alkynes *Tryptamines. Biochem Soc Trans 1991;19(1):215
N-((2,3-dihydro-1,4-benzodioxin-2-yl)methyl)-5-methoxy-1H-indole-3-ethanamine  116729-30-7   *Dioxins *Tryptamines Receptors, Serotonin. Eur J Pharmacol 1989;173(2-3):189
tryptamine-4,5-dione  108560-71-0   *Tryptamines *Indolequinones. J Pharmacol Exp Ther 1989;250(1):141
tryptamide  29876-14-0   *Tryptamines Niacinamide/*analogs & derivatives. Pol J Pharmacol Pharm 1987;39(6):725
luzindole  117946-91-5 Acetamide, N-(2-(2-(phenylmethyl)-1H-indol-3-yl)ethyl)  *Tryptamines. J Pharmacol Exp Ther 1988;246(3):902
N,N-dipropylcarboxamidotryptamine  74885-25-9   *Tryptamines. J Cardiovasc Pharmacol 1988;11(4): 432
N-cyanoethyltryptamine  105115-85-3   *Tryptamines. Proc West Pharmacol Soc 1987;30:307
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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