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Tuftsin

More information in Books or onNLM PubMed
Definition: N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.     
Pharmacological Action Immunologic Factors 		Other names Taftsin; L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine; L-Thr-L-Lys-L-Pro-L-Arg
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tuftsin-AZT conjugate  0   Tuftsin/*analogs & derivatives Zidovudine/*analogs & derivatives. J Pept Sci 2005 Jan;11(1):37-44
N-palmitoyl-amino-ethyl-rigin amide  0   Tuftsin/*analogs & derivatives. Int Immunopharmacol 2001 May;1(5):843-55
N-cholestanyl-amino-ethyl-rigin amide  0   Tuftsin/*analogs & derivatives. Int Immunopharmacol 2001 May;1(5):843-55
tuftsin-M  94359-48-5   *Ethylenediamines Tuftsin/*analogs & derivatives. Experientia 1992 Oct 15;48(10):994-8
tuftsinyl-n-hexylamide  144022-57-1   Tuftsin/*analogs & derivatives. Pol J Pharmacol Pharm 1991 Jul-Aug;43(4):281-8
tuftsinyl-n-heptylamide  144022-55-9   Tuftsin/*analogs & derivatives. Pol J Pharmacol Pharm 1991 Jul-Aug;43(4):281-8
tuftsin, Hyp(3)  0   Tuftsin/*analogs & derivatives. Int J Pept Protein Res 1991 Aug;38(2):176-80
H-Thr-(psi)(NHCO)Lys-Pro-Arg-OH  136981-77-6   Tuftsin/*analogs & derivatives. J Med Chem 1991;34(12):3372
tuftsin, Leu(1)  56694-23-6   Tuftsin/*analogs & derivatives. Int J Biochem 1991;23(5-6):627
2-acetamido-2-deoxygalactopyranosyl tuftsin  0   *Glycopeptides Tuftsin. Int J Pept Protein Res 1991;37(2):112
polytuftsin  112592-90-2 L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-, homopolymer  *Polymers *Tuftsin Drug Carriers. Int J Pept Protein Res 1987;30(1):54
tuftsinyltuftsin, Lys(4)  88171-14-6   Tuftsin/*analogs & derivatives. Life Sci 1985;37(17):1649
tuftsin, (3,4-dehydro-Pro)(3)  91502-65-7 L-Arginine, N2-(3,4-didehydro-1-(N2-L-threonyl-L-lysyl)-L-prolyl)-, (S)  Tuftsin/*analogs & derivatives. Peptides (Fayetteville) 1984;5(3):489
tuftsin, Lys(4)  63138-91-0   Tuftsin/*analogs & derivatives. Ann NY Acad Sci 1983;419:207
tuftsin, Lys-Pro-Arg  0   Tuftsin/*analogs & derivatives. Ann NY Acad Sci 1983;419:35
tuftsin, Pro-Arg  0   Tuftsin/*analogs & derivatives. Ann NY Acad Sci 1983;419;35
tuftsin, Arg  0   Tuftsin/*analogs & derivatives. Ann NY Acad Sci 1983;419:35
tuftsinyltuftsin  80938-76-7 L-Arginine, N2-(1-(N2-(N-(N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-L-arginyl)-L-threonyl)-L-lysyl)-L-prolyl)  Tuftsin/*analogs & derivatives. Mol Cell Biochem 1981;41:3
tuftsin receptor  0   *Receptors, Immunologic Tuftsin. Life Sci 1981;28(10):1081
tuftsin, Arg(3)  75929-73-6 L-Arginine, N2-(N2-(N2-L-threonyl-L-lysyl)-D-arginyl)  Tuftsin/*analogs & derivatives. Experientia 1981;37(1):76
leukokininogen  73020-19-6 Leukokininogen  *Protein Precursors *Tuftsin. Adv Exp Med Biol 1979;120B:205; Biochem Pharmacol 28(7):1043;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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